Investigation of a cryptic ligand binding site on Plasmodium falciparum Hsp90. [PDF]
Bioorg Med ChemMansfield CR +3 more
europepmc +1 more source
Purification of the α Subunit of Avian Myeloblastosis Virus DNA Polymerase by Polyuridylic Acid-Sepharose [PDF]
, 1976 Duane P. Grandgenett
openalex +1 more source
High molecular thyrotrophin ("big"-TSH) from human pituitaries : Preparation and partial characterization [PDF]
, 1977 Erhardt, F., Scriba, Peter Christian
core +1 more source
Human FASTK preferentially binds single‐stranded and G‐rich RNA
The FEBS Journal, EarlyView.Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak +7 more
wiley +1 more source
Isolation, purification, and characterization of polysaccharides from <i>Dendrobium findlayanum</i>: biological activities and potential therapeutic applications. [PDF]
Front NutrChen J +11 more
europepmc +1 more source
The fractionation of t-RNA on N,N′-bis(3-aminopropyl)-piperazine substituted-Sepharose
, 1974 R. Leberman +2 more
openalex +2 more sources
Further Studies on the Identification of the Subcomponents of the First Component of Complement After Affinity Chromatography of Human Serum on IgG-Sepharose [PDF]
, 1977 Patrick Taylor +3 more
openalex +1 more source
Modifying inhibitor specificity for homologous enzymes by machine learning
The FEBS Journal, EarlyView.We present a machine learning method for the design of selective enzyme inhibitors, reducing experimental effort thus accelerating the development of targeted therapeutics. Trained on existing data for three related matrix metalloproteinases (MMPs), our method successfully designed a novel inhibitor variant with enhanced selectivity for one MMP over ...
Dor S. Gozlan +6 more
wiley +1 more source
Myeloperoxidase Enzyme Activity in Feces Reflects Endoscopic Severity in Inflammatory Bowel Disease. [PDF]
Inflamm Bowel DisBorichevsky GM +8 more
europepmc +1 more source