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The problem of sepsis and septic shock has recently become more and more actual. In obstetrics and gynaecology, the number of cases of sepsis has more than doubled over the past 10 years.
V. O. Bitsadze+13 more
doaj +4 more sources
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). [PDF]
IMPORTANCE Septic shock currently refers to a state of acute circulatory failure associated with infection. Emerging biological insights and reported variation in epidemiology challenge the validity of this definition.
M. Shankar-Hari+8 more
semanticscholar +3 more sources
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 [PDF]
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened.
A. Rhodes+64 more
semanticscholar +7 more sources
ObjectiveTo provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008.DesignA consensus committee of 68 international experts representing 30 international organizations was ...
Andrew Rhodes+2 more
exaly +2 more sources
Association of metformin administration after septic shock with short-term and long-term survival in septic shock patients with diabetes [PDF]
Background In addition to glycemic control, the anti-inflammatory effects and protective effect of metformin on sepsis have been reported in animal studies, which may be beneficial for patients with septic shock.
Bo-Yeong Jin+6 more
doaj +2 more sources
Background This study investigated the clinical value of interleukin-6 (IL-6), pentraxin 3 (PTX3), and procalcitonin (PCT) in patients with sepsis and septic shock diagnosed according to the Third International Consensus Definitions for Sepsis and Septic
Juhyun Song+6 more
doaj +2 more sources
Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock: The VANISH Randomized Clinical Trial. [PDF]
IMPORTANCE Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative.
A. Gordon+12 more
semanticscholar +8 more sources
Adjunctive Glucocorticoid Therapy in Patients with Septic Shock
Balasubramanian Venkatesh+2 more
exaly +2 more sources
The objective: to assess the information value of proadrenomedullin (PAM), once measured upon admission to ICU in predicting mortality and differential diagnosis of septic and hypovolemic shock.Subjects and Methods.
V. А. Rudnov+5 more
doaj +1 more source
Background: Three different phenotypes of septic shock based on changes in blood pressure and lactate are recognized in people. Dysoxic shock, representing the combination of fluid-refractory hypotension and hyperlactatemia, is characterized by greater ...
Roberta Troia+7 more
doaj +1 more source