Results 1 to 10 of about 997,918 (264)

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

open access: yesIntensive Care Medicine, 2013
ObjectiveTo provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008.DesignA consensus committee of 68 international experts representing 30 international organizations was ...
Andrew Rhodes   +2 more
exaly   +2 more sources

Sepsis and septic shock

open access: yesNature Reviews Disease Primers, 2016
Lyle L Moldawer   +2 more
exaly   +2 more sources

2023 Update on Sepsis and Septic Shock in Adult Patients: Management in the Emergency Department

open access: yesJournal of Clinical Medicine, 2023
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that requires timely management to reduce mortality. This review aims to update physicians with regard to the main pillars of treatment for this insidious condition ...
M. Guarino   +6 more
semanticscholar   +1 more source

Restriction of Intravenous Fluid in ICU Patients with Septic Shock.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Intravenous fluids are recommended for the treatment of patients who are in septic shock, but higher fluid volumes have been associated with harm in patients who are in the intensive care unit (ICU). METHODS In this international, randomized
T. Meyhoff   +67 more
semanticscholar   +1 more source

Lactylated Histone H3K18 as a Potential Biomarker for the Diagnosis and Predicting the Severity of Septic Shock

open access: yesFrontiers in Immunology, 2022
Objective To date, there are no studies regarding the lactylation profile and its role in critically ill patients. Thus, we aimed to examine expression of histone H3 lysine 18 (H3K18) lactylation and its role in patients with septic shock.
X. Chu   +13 more
semanticscholar   +1 more source

Frequency and mortality of sepsis and septic shock in China: a systematic review and meta-analysis

open access: yesBMC Infectious Diseases, 2022
Background Sepsis, a life-threatening organ dysfunction induced by infection, is a major public health problem. This study aimed to evaluate the frequency and mortality of sepsis, severe sepsis, and septic shock in China.
Yan-Cun Liu   +8 more
semanticscholar   +1 more source

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

open access: yesPediatric Critical Care Medicine, 2020
Supplemental Digital Content is available in the text. Objectives: To develop evidence-based recommendations for clinicians caring for children (including infants, school-aged children, and adolescents) with septic shock and other sepsis-associated organ
S. Weiss   +50 more
semanticscholar   +1 more source

Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019— results from a systematic review and meta-analysis

open access: yesCritical Care, 2020
Background Sepsis and septic shock remain drivers for mortality in critically ill patients. The heterogeneity of the syndrome hinders the generation of reproducible numbers on mortality risks. Consequently, mortality rates range from 15 to 56%.
M. Bauer   +5 more
semanticscholar   +1 more source

Management of sepsis and septic shock in the emergency department

open access: yesInternal and Emergency Medicine, 2021
Early management of sepsis and septic shock is crucial for patients’ prognosis. As the Emergency Department (ED) is the place where the first medical contact for septic patients is likely to occur, emergency physicians play an essential role in the early
F. Gavelli, L. Castello, G. Avanzi
semanticscholar   +1 more source

Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

open access: yesCritical Care, 2021
Background Timely administration of antibiotics is one of the most important interventions in reducing mortality in sepsis. However, administering antibiotics within a strict time threshold in all patients suspected with sepsis will require huge amount ...
Y. Im   +38 more
semanticscholar   +1 more source

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