Results 1 to 10 of about 100,466 (204)

Control groups in recent septic shock trials : a systematic review [PDF]

, 2016
The interpretation of septic shock trial data is profoundly affected by patients, control intervention, co-interventions and selected outcome measures. We evaluated the reporting of control groups in recent septic shock trials.
Hjortrup, Peter Buhl, Jakob, Stephan M., Perner, Anders, Pettilä, Ville, Takala, Jukka, Wilkman, Erika   +5 more
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Specific Removal of Monocytes from Peripheral Blood of Septic Patients by Polymyxin B-immobilized Filter Column [PDF]

, 2009
Lipopolysaccharide (LPS) is one of the major causes of septic shock. The polymyxin B-immobilized filter column (PMX) was developed for the adsorption of endotoxin by direct hemoperfusion and has been used for the treatment of LPS-induced septic shock. In
Iwagaki, Hiromi, Katayama, Hiroshi, Mori, Shuji, Morita, Kiyoshi, Nishibori, Masahiro, Ohtsuka, Aiji, Saito, Shinya, Takahashi, Hide K., Tanaka, Noriaki   +8 more
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The Physiological Basis for Vitamin C as a Potential Treatment for Sepsis [PDF]

, 2019
Accounting for one third of all hospital patient deaths in America, sepsis remains one of the most deadly and complicated conditions that healthcare providers treat.
Johnston, Jennifer
core   +1 more source

Sepsis-induced cardiomyopathy: a review of pathophysiologic mechanisms. [PDF]

, 2010
Cardiac dysfunction is a well-recognized complication of severe sepsis and septic shock. Cardiac dysfunction in sepsis is characterized by ventricular dilatation, reduction in ejection fraction and reduced contractility.
Chokkalingam Mani, Bhalaghuru, Flynn, Anthony, Mather, Paul J   +2 more
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Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock. The VANISH Randomized Clinical Trial [PDF]

, 2016
IMPORTANCE: Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative.
Andrews, P, Anjum, A, Anjum, A, Ashby, D, Ashby, D, Ashby, D, Aya, HD, Banach, D, Bangalan, J, Banks, F, Bassford, C, Beale, R, Bellingan, G, Bewley, J, Birch, S, Bland, M, Bolger, C, Brett, S, Brett, S, Brett, SJ, Brown, A, Bullock, L, Carungcong, J, Cecconi, M, Cecconi, M, Cepkova, M, Cepkova, M, Chan, K, COLLABORATORS, Collier, T, Correia, C, Creary, T, Cross, M, Das, N, Di Tomasso, N, Ebm, C, Errington, E, Frazier, G, Frazier, GJ, Gladas, K, Golder, K, Gordon, A, Gordon, A, Gordon, AC, Gould, T, Griffiths, S, Grimmer, L, Handy, J, Harris, CL, Harrison-Briggs, D, Hauer, V, Hopkins, P, Hurst, T, Iannucceli, F, Jaques, N, Joscak, J, Kirwan, CJ, Kitson, D, Krige, A, Lamb, N, Lei, K, Mason, A, Mason, AJ, Matthew-Thomas, R, McAuley, D, Mellinghoff, J, Mouland, J, Ochelli-Okpue, A, Ostermann, M, Pahary, SM, Perkins, G, Perkins, GD, Pogson, D, Pogson, DG, Prowle, JR, Pulletz, M, Rose, S, Salmon, K, Santhakumaran, S, Santhakumaran, S, Scott, M, Shah, S, Shankar-Hari, M, Skinner, B, Smith, J, Snow, L, Stapleton, C, Stotz, M, Sweet, K, Tamm, T, Templeton, M, Thirunavukkarasu, N, Thirunavukkarasu, N, Ting, J, VANISH Investigators, Vickers, E, Wade-Smith, F, Walden, A, Ward, G, Warwick, J, Watts, T, Wilkinson, K, Williams, S   +102 more
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The effect of goal-directed therapy on mortality in patients with sepsis - earlier is better: A meta-analysis of randomized controlled trials [PDF]

, 2014
__Introduction:__ The Surviving Sepsis Campaign guidelines recommend goal-directed therapy (GDT) for the early resuscitation of patients with sepsis. However, the findings of the ProCESS (Protocolized Care for Early Septic Shock) trial showed no benefit ...
Bakker, J. (Jan), Gu, W.-J. (Wan-Jie), Liu, J.-C. (Jing-Chen), Tang, L. (Lu), Wang, F. (Fei)   +4 more
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Septic Shock

Acta Clinica Belgica, 1975
Abstract The problems associated with septic shock are highlighted, including those which arose during a 3-year prospective study. Mortality in the first year of the study was 71 per cent, falling to 38 per cent in the third year. The reasons, for this fall are detailed. The pattern of survival times changed over the 3 years, giving rise
openaire   +4 more sources

The prevalence of severe sepsis or septic shock in an Irish emergency department [PDF]

, 2018
Severe sepsis and septic shock are among the leading causes of death globally. Despite the central role the emergency department (ED) plays in the early identification of patients presenting to hospital with sepsis, the prevalence of severe sepsis and ...
Fitzpatrick, Fidelma, McDowell, Dermot, McNevin, Ciara, O'Sullivan, Ronan, Wakai, Abel   +4 more
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Role of superantigenic strains in the prognosis of community-acquired methicillin-susceptible Staphylococcus aureus bacteraemia [PDF]

, 2007
Methicillin-susceptible Staphylococcus aureus (MSSA) strains can produce superantigenic toxins that may trigger a massive release of pro-inflammatory cytokines, which are involved in the onset of septic shock. This 1-year prospective pilot study assessed
Denis, F., Desachy, A., Etienne, J., Francois, B., Hashemzadeh, A., Lina, G., Ploy, M.C., Vignon, P.   +7 more
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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. [PDF]

, 2017
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened.
Alhazzani, W, Angus, DC, Annane, D, Antonelli, M, Beale, RJ, Bellinghan, GJ, Bernard, GR, Chiche, J-D, Coopersmith, C, De Backer, DP, Dellinger, RP, Evans, LE, Ferrer, R, French, CJ, Fujishima, S, Gerlach, H, Hidalgo, JL, Hollenberg, SM, Jones, AE, Karnad, DR, Kleinpell, RM, Koh, Y, Kumar, A, Levy, MM, Lisboa, TC, Machado, FR, Marini, JJ, Marshall, JC, Mazuski, JE, McIntyre, LA, McLean, AS, Mehta, S, Moreno, RP, Myburgh, J, Navalesi, P, Nishida, O, Nunnally, ME, Osborn, TM, Perner, A, Plunkett, CM, Ranieri, M, Rhodes, A, Rochwerg, B, Rubenfeld, GD, Schorr, CA, Seckel, MA, Sevransky, JE, Seymour, CW, Shieh, L, Shukri, KA, Simpson, SQ, Singer, M, Sprung, CL, Thompson, BT, Townsend, SR, Van der Poll, T, Vincent, J-L, Wiersinga, WJ, Zimmerman, JL   +58 more
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