Results 41 to 50 of about 1,083,142 (408)
Critical Transitions in Intensive Care Units: A Sepsis Case Study [PDF]
Scientific Reports, 9(1) (2019), 2019 The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this paper, we propose a computational method based on surprise loss (SL) to discover data-driven indicators of such ...
arxiv +1 more source
An Adversarial Domain Separation Framework for Septic Shock Early Prediction Across EHR Systems [PDF]
, 2020 Modeling patient disease progression using Electronic Health Records (EHRs) is critical to assist clinical decision making. While most of prior work has mainly focused on developing effective disease progression models using EHRs collected from an individual medical system, relatively little work has investigated building robust yet generalizable ...
arxiv +1 more source
Journal of the American Medical Association (JAMA), 2016 IMPORTANCE The Third International Consensus Definitions Task Force defined sepsis as "life-threatening organ dysfunction due to a dysregulated host response to infection." The performance of clinical criteria for this sepsis definition is unknown ...
C. Seymour +12 more
semanticscholar +1 more source
Catastrophic health care expenditure due to septic shock and dengue shock in Vietnam [PDF]
, 2019 BACKGROUND: The cost of treatment for infectious shock in intensive care in Vietnam is unknown. METHODS: We prospectively investigated hospital bills for adults treated for septic and dengue shock in Vietnam and calculated the proportion who faced ...
Chau Nguyen, VV +5 more
core +2 more sources
Hereditas, 2021 Background Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognostic sign to septic patients.
Yun Tang +6 more
doaj +1 more source
Journal of the American Medical Association (JAMA), 2020 Importance The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. Objective To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ ...
A. Moskowitz +20 more
semanticscholar +1 more source
Risk factors and outcomes for ineffective empiric treatment of sepsis caused by gram-negative pathogens: Stratification by onset of infection [PDF]
, 2017 Sepsis and septic shock remain serious consequences of infections, with reported mortality rates in excess of 40 percent. Timely antibiotic therapy in cases of sepsis and septic shock is recognized as an important determinant of outcome.
Hampton, Nicholas +2 more
core +2 more sources
Terlipressin or norepinephrine in septic shock: do we have the answer? [PDF]
, 2019 Comment on Terlipressin versus norepinephrine as infusion in patients with septic shock: a multicentre, randomised, double-blinded trial.
Russell, James A., Williams, Mark D.
core +1 more source
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
, 2001 Background Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with oxygen demand.
Manuel +15 more
semanticscholar +1 more source
Annals of Intensive Care, 2021 Background Baseline characteristics and disease severity of patients with septic shock according to the new Sepsis-3 definition may differ from patients that only comply with the Sepsis-2 definition.
Joris Vermassen +4 more
doaj +1 more source