Results 41 to 50 of about 1,087,361 (389)

Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. Objective To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ ...
A. Moskowitz, David T. Huang, P. Hou, Jonathan Gong, P. Doshi, A. Grossestreuer, L. Andersen, L. Ngo, R. Sherwin, K. Berg, M. Chase, M. Cocchi, Jessica B. McCannon, Mark A. Hershey, A. Hilewitz, M. Korotun, L. Becker, R. Otero, J. Uduman, Ayan Sen, M. Donnino   +20 more
semanticscholar   +1 more source

Risk factors and outcomes for ineffective empiric treatment of sepsis caused by gram-negative pathogens: Stratification by onset of infection [PDF]

, 2017
Sepsis and septic shock remain serious consequences of infections, with reported mortality rates in excess of 40 percent. Timely antibiotic therapy in cases of sepsis and septic shock is recognized as an important determinant of outcome.
Hampton, Nicholas, Kollef, Marin, Micek, Scott T   +2 more
core   +2 more sources

Characteristics and Outcomes of Patients with Vasoplegic Versus Tissue Dysoxic Septic Shock [PDF]

, 2013
Background: The current consensus definition of septic shock requires hypotension after adequate fluid challenge or vasopressor requirement. Some patients with septic shock present with hypotension and hyperlactatemia greater than 2 mmol/L (tissue ...
Jones, Alan E, Kline, Jeffrey A., Puskarich, Michael A, Shapiro, Nathan I, Sterling, Sarah A, Summers, Richard L, Trzeciak, Stephen   +6 more
core   +1 more source

Impact of Empirical Antibiotic Regimens on Mortality in Neutropenic Patients with Bloodstream Infection Presenting with Septic Shock

Antimicrobial Agents and Chemotherapy, 2021
We analyzed risk factors for mortality in febrile neutropenic patients with bloodstream infections (BSI) presenting with septic shock and assessed the impact of empirical antibiotic regimens.
Mariana Chumbita, P. Puerta-Alcalde, C. Gudiol, Nicole García-Poutón, J. Laporte-Amargós, A. Ladino, A. Albasanz-Puig, Cristina Helguera, A. Bergas, I. Grafia, E. Sastre, M. Suárez-Lledó, X. Durà, Carl Jordan, F. Marco, M. Condom, P. Castro, J. Martinez, J. Mensa, Á. Soriano, J. Carratalá, C. García-Vidal   +21 more
semanticscholar   +1 more source

Terlipressin or norepinephrine in septic shock: do we have the answer? [PDF]

, 2019
Comment on Terlipressin versus norepinephrine as infusion in patients with septic shock: a multicentre, randomised, double-blinded trial.
Russell, James A., Williams, Mark D.
core   +1 more source

Characteristics of Sepsis-2 septic shock patients failing to satisfy the Sepsis-3 septic shock definition: an analysis of real-time collected data

Annals of Intensive Care, 2021
Background Baseline characteristics and disease severity of patients with septic shock according to the new Sepsis-3 definition may differ from patients that only comply with the Sepsis-2 definition.
Joris Vermassen, Johan Decruyenaere, Liesbet De Bus, Pieter Depuydt, Kirsten Colpaert   +4 more
doaj   +1 more source

Is there NO treatment for severe sepsis? [PDF]

, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

, 2001
Background Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance oxygen delivery with oxygen demand.
Manuel, Ivers, Ryant, Guyen, Uzanne, Avstad, Ulie, Essler, Lexandria, Uzzin, Ernhard, Noblich, Dward, Eterson, Ichael, Omlanovich   +15 more
semanticscholar   +1 more source

Tricuspid Annular Plane of Systolic Excursion for the Evaluation of Patients with Severe Sepsis and Septic Shock [PDF]

, 2020
Introduction: Sepsis is a systemic infection that can rapidly progress into multi organ failure and shock if left untreated. Previous studies have demonstrated the utility of point of care ultrasound (POCUS) in the evaluation of patients with sepsis ...
Ali, Qumber, Fischetti, Chanel, Fox, John C., Lahham, Shadi, Lee, Clifton, Moeller, John, Saadat, Soheil, Thompson, Maxwell   +7 more
core  

Predictors of septic shock in patients with methicillin-resistant Staphylococcus aureus bacteremia [PDF]

, 2012
SummaryObjectivesRisk factors for septic shock associated with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia are not well described.
Bauer, Seth R., Lam, Simon W., Neuner, Elizabeth A.   +2 more
core   +1 more source