Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock
Critical Care, 2018 Background Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS ...
Anatole Harrois +3 more
doaj +1 more source
Detection of sepsis during emergency department triage using machine learning [PDF]
arXiv, 2022 Sepsis is a life-threatening condition with organ dysfunction and is a leading cause of death and critical illness worldwide. Even a few hours of delay in the treatment of sepsis results in increased mortality. Early detection of sepsis during emergency department triage would allow early initiation of lab analysis, antibiotic administration, and other
arxiv
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
International Journal of Pediatrics, 2019 Background. Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have ...
Varsha Vekaria-Hirani +4 more
doaj +1 more source
Empiric Antimicrobial Therapy in Patients with Healthcare-Associated, Hospital-Acquired, or Ventilator-Associated Pneumonia in Septic Shock: Does Antimicrobial Reuse Influence Outcomes? [PDF]
, 2017 Appropriate empiric antimicrobial selection is crucial to the survival of septic shock patients. It is suspected that the use of inadequate empiric therapy occurs commonly in practice.
Stagge, Nicole
core +1 more source
Predictors of septic shock in patients with methicillin-resistant Staphylococcus aureus bacteremia [PDF]
, 2012 SummaryObjectivesRisk factors for septic shock associated with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia are not well described.
Bauer, Seth R. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Usefulness of ischemia-modified albumin in the diagnosis of sepsis/septic shock in the emergency department [PDF]
Clinical and Experimental Emergency Medicine, 2020 Objective No studies have evaluated the diagnostic value of ischemia-modified albumin (IMA) for the early detection of sepsis/septic shock in patients presenting to the emergency department (ED).
Seung Hwa Choo +6 more
doaj +1 more source
Is there NO treatment for severe sepsis? [PDF]
, 2008 Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core +2 more sources
Hydrocortisone plus Fludrocortisone for Adults with Septic Shock
New England Journal of Medicine, 2018 BACKGROUND Septic shock is characterized by dysregulation of the host response to infection, with circulatory, cellular, and metabolic abnormalities.
D. Annane +36 more
semanticscholar +1 more source