Results 211 to 220 of about 229,811 (275)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu   +8 more
wiley   +1 more source

A circovirus-like genomic sequence with unique architecture and phylogenetic relatedness to human-linked viral lineages. [PDF]

open access: yesFront Cell Infect Microbiol
Dai L   +11 more
europepmc   +1 more source

Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates

open access: yesAggregate, Volume 7, Issue 3, March 2026.
This review highlights the construction of AIE active bioconjugates via click chemical or bioorthogonal reactions, and their applications in biosensing, bioimaging, and image‐guided treatment. The challenges and perspectives in the area are also discussed.
Xinzhe Yang   +3 more
wiley   +1 more source

On the Heterochrony and Evolution of Oral Structures in Phyllopharyngean Ciliates (Protista: Ciliophora)

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 91-106, March 2026.
Ontogenetic sequences in phyllopharyngean ciliates. ABSTRACT Heterochronic shifts in developmental sequences of unicellular organisms are rarely considered as mechanisms behind their morphological evolution. Among eukaryotic microbes, ciliates represent a key model group, exhibiting diverse morphologies and developmental trajectories.
Klára Bukovinská, Peter Vďačný
wiley   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu   +9 more
wiley   +1 more source

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