Results 81 to 90 of about 3,847 (182)

Graphs of protein-water hydrogen bond networks to dissect structural movies of ion-transfer microbial rhodopsins

Frontiers in Chemistry, 2023
Microbial rhodopsins are membrane proteins that use the energy absorbed by the covalently bound retinal chromophore to initiate reaction cycles resulting in ion transport or signal transduction.
Éva Bertalan, Ana-Nicoleta Bondar, Ana-Nicoleta Bondar   +2 more
doaj   +1 more source

Recent structural insights into the function of copper nitrite reductases. [PDF]

, 2017
Copper nitrite reductases (CuNiR) carry out the first committed step of the denitrification pathway of the global nitrogen cycle, the reduction of nitrite (NO2(-)) to nitric oxide (NO).
Adman, Adman, Adman, Adman, Antonyuk, Antonyuk, Barrett, Beitlich, Blakeley, Boulanger, Boulanger, Boulanger, Cheung, De Marothy, Demet Kekilli, Dodd, Dodd, Eady, Eady, Ellis, Ellis, Ellis, Ellis, Fujisawa, Fukuda, Fukuda, Fukuda, Fukuda, Fukuda, Fukuda, Garman, Ghosh, Ghosh, Ghosh, Godden, Horrell, Hosseinzadeh, Hough, Hough, Hough, Jacobson, Jacobson, Kekilli, Knowles, Krzemiński, Kukimoto, Kukimoto, Lawton, Leferink, Leferink, Leferink, Li, Lintuluoto, Lintuluoto, McGeehan, Merkle, Merkle, Michael A. Hough, Michalski, Murphy, Murphy, Murphy, Nakano, Nojiri, Nojiri, Nojiri, Owen, Paraskevopoulos, Polsinelli, Richard W. Strange, Sam Horrell, Schlichting, Schlichting, Silaghi-Dumitrescu, Solomon, Solomon, Spence, Strange, Suzuki, Thomson, Tocheva, Tocheva, Tocheva, Usov, Vlasie, von Stetten, Wallace, Wijma, Zumft   +88 more
core   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Ground‐ and Excited‐State Mixed Valency in a 4,4′‐Bipyridine‐Bridged Bimetallic Di‐Ruthenium Complex

European Journal of Inorganic Chemistry, EarlyView.
Photoinduced mixed‐valence interactions across a 4,4′‐bpy bridge were studied. MLCT excited states in the bimetallic complex are longer‐lived than in the monometallic reference, thanks to metal–metal electronic coupling and hole delocalization, but are still shorter than the nanosecond timescale relevant for diffusional reactivity.
Ivana Ramírez‐Wierzbicki, Frank W. Heinemann, Leonardo D. Slep, Alejandro Cadranel   +3 more
wiley   +1 more source

Serial femtosecond crystallography approaches to understanding catalysis in iron enzymes

Current Opinion in Structural Biology, 2022
Enzymes with iron-containing active sites play crucial roles in catalysing a myriad of oxidative reactions essential to aerobic life. Defining the three-dimensional structures of iron enzymes in resting, oxy-bound intermediate and substrate-bound states is particularly challenging, not least because of the extreme susceptibility of the Fe(III) and Fe ...
Jonathan A.R. Worrall, Michael A. Hough
openaire   +3 more sources

Infrared spectroscopy reveals multi-step multi-timescale photoactivation in the photoconvertible protein archetype dronpa [PDF]

, 2018
Photochromic fluorescent proteins play key roles in super-resolution microscopy and optogenetics. The light-driven structural changes that modulate the fluorescence involve both trans-to-cis isomerization and proton transfer. The mechanism, timescale and
Donaldson, Paul, Gil, Agnieszka A., Greetham, Gregory M., Hall, Christopher R., Iuliano, James N., Jones, Garth A., Laptenok, Sergey P., Lukacs, Andras, Meech, Stephen R., Miyawaki, Atsushi, Tonge, Peter J.   +10 more
core   +1 more source

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin [PDF]

, 2019
Bacteriorhodopsin (bR) is a light-driven proton pump. The primary photochemical event upon light absorption is isomerization of the retinal chromophore.
Batyuk, Alexander, Colletier, Jacques-Philippe, Ehrenberg, David, Grünbein, Marie Luise, Heberle, Joachim, Heyne, Karsten, Kovacs, Gabriela Nass, Schlesinger, Ramona, Stensitzki, Till, Yang, Yang   +9 more
core   +1 more source

Quantum State‐Resolved Photodissociation Dynamics Study of Transition‐Metal Carbonyl and Nitrosyl

The Chemical Record, EarlyView.
State‐resolved scattering measurements provide experimental visualization of nuclear motions in reacting molecules. Carbonyls and nitrosyls are typical ligands in most of the transition‐metal complexes, which undergo dissociation upon visible and ultraviolet photoexcitation.
Keigo Nagamori, Hiroyuki Nakata, Hiroshi Kohguchi   +2 more
wiley   +1 more source

Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source [PDF]

, 2016
Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS).
Andreasson, Jakob, Aquila, Andrew, Awel, Salah, Ayyer, Kartik, Barty, Anton, Bean, Richard J., Berntsen, Peter, Bielecki, Johan, Boutet, Sebastien, Bucher, Maximilian, Chapman, Henry N., Daurer, Benedikt J., DeMirci, Hasan, Elser, Veit, Fromme, Petra, Hajdu, Janos, Hantke, Max F., Higashiura, Akifumi, Hogue, Brenda G., Hosseinizadeh, Ahmad, Kim, Yoonhee, Kirian, Richard A., Lan, Ti-Yen, Larsson, Daniel S. D., Liu, Haiguang, Loh, N. Duane, Maia, Filipe R. N. C., Mancuso, Adrian P., Muhlig, Kerstin, Munke, Anna, Nakagawa, Atsushi, Nam, Daewoong, Nelson, Garrett, Nettelblad, Carl, Okamoto, Kenta, Ourmazd, Abbas, Reddy, Hemanth K. N., Rose, Max, Schwander, Peter, Seibert, M. Marvin, Sellberg, Jonas A., Sierra, Raymond G., Song, Changyong, Svenda, Martin, Timneanu, Nicusor, van der Schot, Gijs, Vartanyants, Ivan A., Westphal, Daniel, Wiedorn, Max O., Williams, Garth J., Xavier, Paulraj Lourdu, Yoon, Chun Hong, Zook, James   +52 more
core   +2 more sources