Results 181 to 190 of about 3,653 (216)

Thermal histories of El Médano 300 (EM 300) and Northwest Africa 8155 (NWA 8155): Implications for the diversity of IAB‐ungrouped iron meteorites and their parent bodies

Meteoritics &Planetary Science, Volume 61, Issue 8, Page 1763-1787, August 2026.
Abstract This study provides the first petrographic, crystallographic, and chemical comparison between El Médano 300 (EM 300) and Northwest Africa 8155 (NWA 8155), two particular IAB‐ungrouped iron meteorites. Both contain exceptionally large graphite nodules and “flowers”, providing unique insights into carbon behavior in metallic melts and cooling ...
L. Perez, M. Roskosz, F. Danoix, L. Kern, V. Megevand, C. Brillatz, B. Devouard, J. Gattacceca, M. Gounelle   +8 more
wiley   +1 more source

1‐Aryl‐6,7‐Dimethoxy‐3,4‐Dihydroisoquinoline‐2(1H)‐Sulfonamides as hCA XII Selective Inhibitors: Experimental and Theoretical Studies to Interrogate the Isoform Selectivity

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
Experimental and theoretical studies have disclosed the more relevant structural requirements for effective inhibition and an impressing selectivity toward tumor‐expressed hCA XII isoform over hCA II. Human carbonic anhydrase XII (hCA XII) represents an important pharmacological target for different types of cancer.
Federico Ricci, Anna Di Fiore, Andrea Angeli, Laura De Luca, Francesca Mancuso, Davide Esposito, Giuseppina De Simone, Claudiu T. Supuran, Rosaria Gitto   +8 more
wiley   +1 more source

Single-cell structural biology with intracellular electron crystallography. [PDF]

Nat Commun
Bílá Š, Pinkas D, Khakurel K, Boger J, Bílý T, Hajdu J, Franta Z, de Diego Martinez I, Tuma R, Redecke L, Polovinkin V.   +10 more
europepmc   +1 more source

Novel Inhibitors of Carbonic Anhydrase I and II Identified by High Throughput Virtual Screening and Validated by X‐Ray Crystallography

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
High‐throughput virtual screening identifies novel carbonic anhydrase II ligands from large chemical libraries, enabling rapid hit discovery. Structural validation by X‐ray crystallography confirms the predicted binding modes and reveals key protein–ligand interactions.
Asher L. Brandt, Joseph Venditto, Marta Ferraroni, Claudiu T. Supuran, Andrea Angeli   +4 more
wiley   +1 more source

A Bright and Dynamic Future in Structural Biology. [PDF]

Adv Exp Med Biol
Yang X.
europepmc   +1 more source

Multi-Crystal X-Ray Diffraction (MCXRD) Bridges the Crystallographic Characterisation Gap in Chemistry and Materials Science: Application to MOFs. [PDF]

Angew Chem Int Ed Engl
Smith JP, Smith R, Roseveare TM, Bara D, Thom AJR, Forgan RS, Warren MR, Warren AJ, Owen RL, Brammer L.   +9 more
europepmc   +1 more source

Cefdinir binding to a class A β-lactamase revealed by serial cryo-crystallography. [PDF]

Acta Crystallogr D Struct Biol
Gore G, Prester A, Bartels K, von Stetten D, Schulz EC.   +4 more
europepmc   +1 more source

Room-temperature X-ray fragment screening with serial crystallography. [PDF]

Nat Commun
Günther S, Fischer P, Galchenkova M, Falke S, Reinke PYA, Thekku Veedu S, Rodrigues AC, Senst J, Elinjikkal D, Gumprecht L, Meyer J, Chapman HN, Barthelmess M, Meents A.   +13 more
europepmc   +1 more source

Comparative Structural Analysis of Escherichia Coli Cyay at Room and Cryogenic Temperatures Using Macromolecular and Serial Crystallography. [PDF]

Chembiochem
Shafiei A, Baldir N, Na J, Kim JH, DeMirci H, DeMirci H.   +5 more
europepmc   +1 more source

Evolution of macromolecular crystallography beamlines at the Swiss Light Source and SwissFEL. [PDF]

J Synchrotron Radiat
Wang M.
europepmc   +1 more source