Results 81 to 90 of about 7,626 (235)

The expanding toolkit for structural biology: synchrotrons, X-ray lasers and cryoEM

IUCrJ, 2019
Structural biology continues to benefit from an expanding toolkit, which is helping to gain unprecedented insight into the assembly and organization of multi-protein machineries, enzyme mechanisms and ligand/inhibitor binding.
Stephen P. Muench, Svetlana V. Antonyuk, S. Samar Hasnain   +2 more
doaj   +1 more source

Recent structural insights into the function of copper nitrite reductases. [PDF]

, 2017
Copper nitrite reductases (CuNiR) carry out the first committed step of the denitrification pathway of the global nitrogen cycle, the reduction of nitrite (NO2(-)) to nitric oxide (NO).
Adman, Adman, Adman, Adman, Antonyuk, Antonyuk, Barrett, Beitlich, Blakeley, Boulanger, Boulanger, Boulanger, Cheung, De Marothy, Demet Kekilli, Dodd, Dodd, Eady, Eady, Ellis, Ellis, Ellis, Ellis, Fujisawa, Fukuda, Fukuda, Fukuda, Fukuda, Fukuda, Fukuda, Garman, Ghosh, Ghosh, Ghosh, Godden, Horrell, Hosseinzadeh, Hough, Hough, Hough, Jacobson, Jacobson, Kekilli, Knowles, Krzemiński, Kukimoto, Kukimoto, Lawton, Leferink, Leferink, Leferink, Li, Lintuluoto, Lintuluoto, McGeehan, Merkle, Merkle, Michael A. Hough, Michalski, Murphy, Murphy, Murphy, Nakano, Nojiri, Nojiri, Nojiri, Owen, Paraskevopoulos, Polsinelli, Richard W. Strange, Sam Horrell, Schlichting, Schlichting, Silaghi-Dumitrescu, Solomon, Solomon, Spence, Strange, Suzuki, Thomson, Tocheva, Tocheva, Tocheva, Usov, Vlasie, von Stetten, Wallace, Wijma, Zumft   +88 more
core   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Choosing the optimal spectroscopic toolkit to understand protein function [PDF]

, 2017
Spectroscopy was one of the earliest methods used to study the properties and reactions of proteins, and remains one of the most powerful and widely used approaches to this day. A sometimes bewildering range of spectroscopies is now available, applicable
Andrew, Barth, Benfatto, Berera, Best, Billeter, Bui, Cheung, Dworkowski, D’Angelo, Franco, Glockner, Gossert, Hough, Kern, Kovermann, Kowalska, Kutta, Le Sueur, Levantino, Li, McGeehan, Michael A. Hough, Miles, Murakawa, Orville, Ritter, Robustelli, Roder, Rygula, Strange, Strange, Svistunenko, Teilum, von Stetten, Wallace, Wishart, Wuthrich, Yang, Yano, Zuiderweg   +40 more
core   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Time-resolved structural studies with serial crystallography: A new light on retinal proteins

Structural Dynamics, 2015
Structural information of the different conformational states of the two prototypical light-sensitive membrane proteins, bacteriorhodopsin and rhodopsin, has been obtained in the past by X-ray cryo-crystallography and cryo-electron microscopy.
Valérie Panneels, Wenting Wu, Ching-Ju Tsai, Przemek Nogly, Jan Rheinberger, Kathrin Jaeger, Gregor Cicchetti, Cornelius Gati, Leonhard M. Kick, Leonardo Sala, Guido Capitani, Chris Milne, Celestino Padeste, Bill Pedrini, Xiao-Dan Li, Jörg Standfuss, Rafael Abela, Gebhard Schertler   +17 more
doaj   +1 more source

Generalized crystallography [PDF]

, 2002
X-ray crystal structure analysis can now be seen as a special kind of microscopy which is being extended to the recognition and examination of many kinds of ordered structure more general than crystals and which leads to their synthesis or construction ...
Mackay, Alan L.
core   +1 more source

Operando X‐Ray Diffraction and Total Scattering Characterization of Battery Materials: Not Just a Pretty Picture

Advanced Energy Materials, EarlyView.
This review focuses on operando studies of battery materials by X‐ray diffraction (XRD) and total X‐ray scattering (TXS). This work highlights potential pitfalls and identify best‐practices for operando studies and reviews some unusual experiments to illustrate how these methods can be applied beyond the evaluation of the early‐stage cycling mechanisms
Amalie Skurtveit, Eira Tiberg North, Izar Capel Berdiell, Wouter Van Beek, David S. Wragg, Alexey Y. Koposov   +5 more
wiley   +1 more source

The current status and future prospects of the Synchrotron Radiation Protein Crystallography Core Facility at NSRRC: a focus on the TPS 05A, TPS 07A and TLS 15A1 beamlines

Journal of Synchrotron Radiation
The Synchrotron Radiation Protein Crystallography Core Facility (SPXF) at the National Synchrotron Radiation Research Center has been pivotal in advancing structural biology research in Taiwan.
Chung-Kuang Chou, Chien-Chang Tseng, Cheng-Hung Chiang, Yi-Hui Chen, Yi-Chun Liu, Chen-Ying Huang, Chun-Hsiung Chao, Chun-Hsiang Huang   +7 more
doaj   +1 more source

Analysis of Multi-Hit Crystals in Serial Synchrotron Crystallography Experiments Using High-Viscosity Injectors

Crystals, 2021
Serial Synchrotron Crystallography (SSX) is rapidly emerging as a promising technique for collecting data for time-resolved structural studies or for performing room temperature micro-crystallography measurements using micro-focused beamlines.
Marjan Hadian-Jazi, Peter Berntsen, Hugh Marman, Brian Abbey, Connie Darmanin   +4 more
doaj   +1 more source