Results 71 to 80 of about 7,626 (235)

Dose, exposure time, and resolution in Serial X-ray Crystallography

, 2007
The resolution of X-ray diffraction microscopy is limited by the maximum dose that can be delivered prior to sample damage. In the proposed Serial Crystallography method, the damage problem is addressed by distributing the total dose over many identical ...
Chapman, H. N., Doak, R. B., Fromme, P., Hembree, G., Howells, M., Rez, P., Schmidt, K., Shapiro, D., Spence, J. C. H., Starodub, D., Weierstall, U.   +10 more
core   +1 more source

Sample delivery for serial crystallography at free-electron lasers and synchrotrons [PDF]

Acta Crystallographica Section D Structural Biology, 2019
The high peak brilliance and femtosecond pulse duration of X-ray free-electron lasers (XFELs) provide new scientific opportunities for experiments in physics, chemistry and biology. In structural biology, one of the major applications is serial femtosecond crystallography.
Grünbein, M., Nass Kovacs, G.
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Fixed-Target Pink-Beam Serial Synchrotron Crystallography at Pohang Light Source II

Crystals, 2023
Serial crystallography (SX) enables the determination of the structure of macromolecules or small molecules with minimal radiation damage. In particular, biomolecule structures determined using the SX technique have the advantage of providing room ...
Yongsam Kim, Ki Hyun Nam
doaj   +1 more source

High-speed fixed-target serial virus crystallography [PDF]

, 2017
We report a method for serial X-ray crystallography at X-ray free-electron lasers (XFELs), which allows for full use of the current 120-Hz repetition rate of the Linear Coherent Light Source (LCLS). Using a micropatterned silicon chip in combination with
Alonso-Mori, R, Brewster, AS, Damiani, DS, David, C, Duman, R, Fischer, P, Fry, EE, Ginn, HM, Harlos, K, Kelly, J, Kotecha, A, Meents, A, Meyer, J, Michels-Clark, T, Nelson, S, Pakendorf, T, Reime, B, Ren, J, Roedig, P, Rowlands, DJ, Sauter, NK, Sikorsky, M, Stuart, DI, Sutton, G, Vartiainen, I, Wagner, A, Walter, TS, Warmer, M, Young, ID   +28 more
core   +2 more sources

Creating Ti–Fe α/β Alloys by Diffusion‐Driven Solid‐State Processing

Advanced Engineering Materials, EarlyView.
This study proposes making alloys containing fast diffusing elements that are difficult to produce by ingot metallurgy, by diffusion‐driven solid‐state HIP processing of elemental powders and low‐temperature homogenisation. Here, novel Fe‐Ti α–β alloys are formed having fine α–β lamellae, a small β prior grain size without significant intermetallics ...
Jiaqi Xu, Xun Zhang, Jack M. Donoghue, Albert D. Smith, Rahul Unnikrishnan, Rhys Thomas, Vahid Nekouie, Jie Luo, Dongchen Hu, Michael Preuss, Philip J. Withers   +10 more
wiley   +1 more source

An Electrospinning Sample Delivery Device for Synchrotron-Based Biomacromolecule Serial Crystallography Research

Quantum Beam Science
Serial crystallography is a rapidly advancing experimental technology that has seen significant development in recent years. This technique enables the continuous delivery of a series of protein crystal samples to the X-ray beam, allowing for the ...
Li Yu, Zhijun Wang, Qin Xu, Bo Sun, Qingjie Xiao, Weiwei Wang, Yuzhu Wang, Qisheng Wang, Jianhua He   +8 more
doaj   +1 more source

Kilohertz serial crystallography with the JUNGFRAU detector at a fourth-generation synchrotron source

IUCrJ, 2023
Serial and time-resolved macromolecular crystallography are on the rise. However, beam time at X-ray free-electron lasers is limited and most third-generation synchrotron-based macromolecular crystallography beamlines do not offer the necessary ...
Filip Leonarski, Jie Nan, Zdenek Matej, Quentin Bertrand, Antonia Furrer, Ishkhan Gorgisyan, Monika Bjelčić, Michal Kepa, Hannah Glover, Viktoria Hinger, Thomas Eriksson, Aleksander Cehovin, Mikel Eguiraun, Piero Gasparotto, Aldo Mozzanica, Tobias Weinert, Ana Gonzalez, Jörg Standfuss, Meitian Wang, Thomas Ursby, Florian Dworkowski   +20 more
doaj   +1 more source

Nanoscale mosaicity revealed in peptide microcrystals by scanning electron nanodiffraction. [PDF]

, 2019
Changes in lattice structure across sub-regions of protein crystals are challenging to assess when relying on whole crystal measurements. Because of this difficulty, macromolecular structure determination from protein micro and nanocrystals requires ...
Boyer, David R, Bustillo, Karen C, Ciston, Jim, Gallagher-Jones, Marcus, Glynn, Calina, Mancia, Kevin Canton, Minor, Andrew M, Ophus, Colin, Panova, Ouliana, Rodriguez, Jose A, Zee, Chih-Te   +10 more
core   +3 more sources

Phase‐Pure and Size‐Tunable Tin Halide Perovskite Quantum Dots

Advanced Materials, EarlyView.
A trioctylphosphine oxide modulated protocol allows for the synthesis and study of the optical properties of a broad library of tin halide perovskite quantum dots across multiple A‐ and X‐site compositions with precise size tuning while eliminating unwanted 2D phases.
Ole F. Dressler, Benjamin Aymoz, Sebastian Sabisch, Stefanie Frick, Sebastian Siol, Dmitry N. Dirin, Simon C. Boehme, Maksym V. Kovalenko   +7 more
wiley   +1 more source