Results 61 to 70 of about 701 (107)

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

, 2015
HIV-1 Nef, a protein important for the development of AIDS, has well-characterized effects on host membrane trafficking and receptor downregulation. By an unidentified mechanism, Nef increases the intrinsic infectivity of HIV-1 virions in a host-cell ...
Santoni, Federico, Ajit Chande, Bertorelli, Roberto, Goh, Shih Lin, Antonarakis, Stylianos, Sean M. McCauley, Stylianos E. Antonarakis, Rosa, Annachiara, Serena Ziglio, Roberto Bertorelli, Luban, Jeremy, Shih Lin Goh, Anetta Nowosielska, Veronica De Sanctis, Pizzato, Massimo, Jeremy Luban, De Sanctis, Veronica, McCauley, Sean M, Nowosielska, Anetta, Federico Andrea Santoni, Annachiara Rosa, Massimo Pizzato, Chande, Ajit, Ziglio, Serena   +23 more
core   +1 more source

Lung expression of genes putatively involved in SARS-CoV-2 infection is modulated in cis by germline variants

, 2021
Germline variants in genes involved in SARS-CoV-2 cell entry and in host innate immune responses to viruses may influence the susceptibility to infection. This study used whole-genome analyses of lung tissue to identify polymorphisms acting as expression
Francesca Colombo, Chiara E Cotroneo, Tommaso A Dragani, Nunzia Mangano   +3 more
core  

Mechanism of Phosphatidylserine Lipid Scrambling by Human SERINC3, an HIV-1 Restriction Factor

The HIV-1 restriction factor, hSERINC3, functions as a lipid scramblase, translocating lipids across the bilayer in reconstituted proteoliposomes and the viral envelope.
Voth, Gregory A, Banerjee, Puja, Yeager, Mark   +2 more
core   +1 more source

Endoplasmic Reticulum Stress Could Predict the Prognosis of Cervical Cancer and Regulate the Occurrence of Radiation Mucositis. [PDF]

Dose Response, 2023
Liu X, Song J, Liu H, Sun Z, Ren H, Luo J.   +5 more
europepmc   +1 more source

Genetic and transcriptomic signatures of host control in HIV-1 infection. [PDF]

Retrovirology
Oreshkov S, Thorball CW, Meylan J, Muriset M, Calmy A, Ciuffi A, Elzi L, Nemeth J, Muhammad A, Baumann L, Schmid P, Stöckle M, Alpern D, Swiss HIV Cohort Study, Fellay J, Santoni F.   +15 more
europepmc   +1 more source

miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4. [PDF]

Acta Neuropathol Commun, 2023
Yuan M, Mahmud I, Katsushima K, Joshi K, Saulnier O, Pokhrel R, Lee B, Liyanage W, Kunhiraman H, Stapleton S, Gonzalez-Gomez I, Kannan RM, Eisemann T, Kolanthai E, Seal S, Garrett TJ, Abbasi S, Bockley K, Hanes J, Chapagain P, Jallo G, Wechsler-Reya RJ, Taylor MD, Eberhart CG, Ray A, Perera RJ.   +25 more
europepmc   +1 more source

SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways. [PDF]

Sci Signal, 2021
Zeng C, Waheed AA, Li T, Yu J, Zheng YM, Yount JS, Wen H, Freed EO, Liu SL.   +8 more
europepmc   +1 more source

Host restriction factors and p17-Driven inflammaging in HIV-1: From molecular pathogenesis to functional cure. [PDF]

AIMS Microbiol
Nitsotolis T, Assimakopoulos SF, Kouriannidi E, Lagadinou M, Papalexandrou A, Ioannou P, Marangos M, Milionis H, Christaki E.   +8 more
europepmc   +1 more source

Restriction of HIV-1 infectivity by interferon and IFITM3 is counteracted by Nef. [PDF]

Sci Adv
Agarwal M, Lai KK, Wilt I, Majdoul S, Jolley AA, Lewinski M, Compton AA.   +6 more
europepmc   +1 more source

Genomic Structural Equation Modeling Reveals Shared Genetic Architecture and Pleiotropic Hub Genes of Sepsis-Induced Cardiomyopathy. [PDF]

Genes (Basel)
Fang M, Zhou B, Yu P, Long X, Shao M.
europepmc   +1 more source