Benzophenone Semicarbazones as Potential alpha-glucosidase and Prolyl Endopeptidase Inhibitor: In-vitro free radical scavenging, enzyme inhibition, mechanistic, and molecular docking studies [PDF]
$\alpha$-glucosidase and prolylendopeptidase has altered expression and activity patterns in neurological disease, type 2diabetes respectively and several cancers. Here we screened a series 1-29 benzophenone semicarbazone derivatives for in vitro free radical scavenging, alpha-glucosidase and prolylendopeptidase inhibition activities. Seven derivatives
arxiv
The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 Å resolution [PDF]
Background: Staphylococcal epidermolytic toxins A and B (ETA and ETB) are responsible for the staphylococcal scalded skin syndrome of newborn and young infants; this condition can appear just a few hours after birth.
Bilwes, Alexandrine+10 more
core +2 more sources
Harris-Viehmann conjecture for Hodge-Newton reducible Rapoport-Zink spaces [PDF]
Rapoport-Zink spaces, or more generally local Shimura varieties, are expected to provide geometric realization of the local Langlands correspondence via their $l$-adic cohomology. Along this line is a conjecture by Harris and Viehmann, which roughly says that when the underlying local Shimura datum is not basic, the $l$-adic cohomology of the local ...
arxiv +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Substrate specificity and structural investigation into PepO and PepW : two peptidases from Lactobacillus rhamnosus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
The proteolytic systems of lactic acid bacteria have important roles in the maturation and flavour development of cheese. Lactic acid bacteria pepetidases contribute to the taste of cheese through the production of low-molecular weight peptides and free ...
Yates, Karen Maree
core
Amino acid sequence of the chymotryptic protease II from the larvae of the hornet, Vespa crabro [PDF]
The covalent structure of the chymotrypsin II from the larvae of the hornet, Vespa crabro, has been determined. The sequence has been deduced from 3 sets of overlapping peptides generated by trypsin after modification of the lysine or arginine residues ...
De Haë+10 more
core +2 more sources
Investigations on luminal proteinases of grubs of red palm weevil, hynchophorus ferrugineus (Olivier) infesting coconut revealed presence of two endodpeptidases viz., trypsin (BApNA-ase activity) and elastase-like chymotrypsin (SAAPLpNA-ase activity) in
R. A. Joseph+2 more
semanticscholar +1 more source
The Role of Microbial Aspartic Protease Enzyme in Food and Beverage Industries
Proteases represent one of the three largest groups of industrial enzymes and account for about 60% of the total global enzymes sale. According to the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology, proteases are ...
Jermen Mamo, Fassil Assefa
doaj +1 more source
The family of Deg/HtrA proteases in plants
Background The Deg/HtrA family of ATP-independent serine endopeptidases is present in nearly all organisms from bacteria to human and vascular plants. In recent years, multiple deg/htrA protease genes were identified in various plant genomes.
Schuhmann Holger+2 more
doaj +1 more source
On certain extensions of vector bundles in p-adic geometry [PDF]
Given two arbitrary vector bundles on the Fargues-Fontaine curve, we give an explicit criterion in terms of Harder-Narasimhan polygons on whether they realize a semistable vector bundle as their extensions. Our argument is largely combinatorial and builds upon the dimension analysis of certain moduli spaces of bundle maps developed in [BFH+22].
arxiv