Results 21 to 30 of about 95,130 (254)
REVIEW OF SERINE PROTEASE INHIBITORS: DEVELOPMENT AND APPLICATIONS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2023 A class of enzymes known as proteases is responsible for catalyzing the breakdown of covalent peptide bonds. Proteases account for almost 2% of the genes in humans, infectious organisms, and other forms of life.
Mai Ramadan
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Frontiers in Cellular and Infection Microbiology, 2021 The pathobiont Streptococcus pneumoniae causes life-threatening diseases, including pneumonia, sepsis, meningitis, or non-invasive infections such as otitis media.
Murtadha Q. Ali +4 more
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Serine Proteases in Rodent Hippocampus [PDF]
Journal of Biological Chemistry, 1998 Brain serine proteases are implicated in developmental processes, synaptic plasticity, and in disorders including Alzheimer's disease. The spectrum of the major enzymes expressed in brain has not been established previously. We now present a systematic study of the serine proteases expressed in adult rat and mouse hippocampus.
Davies, Ben J. +4 more
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Extracellular Pneumococcal Serine Proteases Affect Nasopharyngeal Colonization
Frontiers in Cellular and Infection Microbiology, 2021 Streptococcus pneumoniae has evolved versatile strategies to colonize the nasopharynx of humans. Colonization is facilitated by direct interactions with host cell receptors or via binding to components of the extracellular matrix.
Murtadha Q. Ali +7 more
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Peptidyl Activity-Based Probes for Imaging Serine Proteases
Frontiers in Chemistry, 2021 Proteases catalyze the hydrolysis of peptide bonds. Products of this breakdown mediate signaling in an enormous number of biological processes. Serine proteases constitute the most numerous group of proteases, accounting for 40%, and they are prevalent ...
Paulina Kasperkiewicz
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European Journal of Entomology, 2023 Rhyzopertha dominica is a pest that uses trypsin-like serine protease enzymes to hydrolyse the proteins in the cereal grains on which it feeds. The present study reveals for the first time that that there are both glycosylated and non-glycosylated serine
Fernanda S. ZAVALA-IBARRA +9 more
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Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea. [PDF]
PLoS ONE, 2014 Membrane-bound serine proteases play important roles in different biological processes. Their regulation by endogenous inhibitors is poorly understood.
Nicolas Faller +2 more
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Microbiology Spectrum, 2023 Serine proteases are a group of important hydrolytic enzymes that play vital roles in various cellular processes in fungi. In this study, the S8 serine protease-encoding gene CrKP43 was identified in the highly efficient Clonostachys chloroleuca 67–1 ...
Binna Lv +4 more
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Activity-Based Probes to Utilize the Proteolytic Activity of Cathepsin G in Biological Samples
Frontiers in Chemistry, 2021 Neutrophils, migrating to the site of infection, are able to release serine proteases after being activated. These serine proteases comprise cathepsin G (CatG), neutrophil elastase protease 3 (PR3), and neutrophil serine protease 4 (NSP4). A disadvantage
Timo Burster +3 more
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Neurobiology of Disease, 2014 Although tissue plasminogen activator (tPA) is known to promote neuronal remodeling in the CNS, no mechanism of how this plastic function takes place has been reported so far.
Sighild Lemarchant +17 more
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