Results 31 to 40 of about 72,685 (290)

Characterization of plasmin, plasminogen and plasminogen activator in goat milk

Italian Journal of Animal Science, 2011
Plasmin (PL), a serine-proteinase, appears to be the predominant native proteinase in milk and it is mainly associated to casein micelles which represent its substrate (Bastian and Brown, 1996). Plasmin occurs in milk together with its inactive zymogene,
F. Polidori, G. Lebbroni, P. Polidori, F. Fantuz   +3 more
doaj   +1 more source

Midgut serine proteinases and alternative host plant utilization in Pieris brassicae L.

Frontiers in Physiology, 2015
Pieris brassicae L. is a serious pest of cultivated crucifers in several parts of theworld. Larvae of P. brassicae also feed prolifically on garden nasturtium (Tropaeolummajus L., of the family Tropaeolaceae).
Rakesh eKumar, Rakesh eKumar, Usha eBhardwaj, Usha eBhardwaj, Pawan eKumar, Sudeshna eMazumdar-Leighton   +5 more
doaj   +1 more source

Induction of Tumor Necrosis Factor (TNF) Release from Subtypes of T Cells by Agonists of Proteinase Activated Receptors

Mediators of Inflammation, 2013
Serine proteinases have been recognized as playing an important role in inflammation via proteinase activated receptors (PARs). However, little is known about the influence of serine proteinases and PARs on TNF secretion from highly purified T cells.
Haiwei Yang, Tao Li, Jifu Wei, Huiyun Zhang, Shaoheng He   +4 more
doaj   +1 more source

Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity

Virology Journal, 2005
Through the use of transient expression assays and directed genetics, the vaccinia virus (VV) I7L gene product has been implicated as the major maturational proteinase required for viral core protein cleavage to occur during virion assembly.
Hruby Dennis E, Byrd Chelsea M
doaj   +1 more source

The use of phenyl-Sepharose for the affinity purification of proteinases [PDF]

, 1993
Phenyl-Sepharose is most often used as an adsorbent for hydrophobic interaction chromatography (HIC). We report on its effective use for the affinity purification of some extracellular thermostable proteinases from bacterial sources.
Daniel, Roy M., Peek, Keith, Prescott, Mark, Veitch, Dallas P.   +3 more
core   +2 more sources

TMPRSS2 as a Key Player in Viral Pathogenesis: Influenza and Coronaviruses

Biomolecules
TMPRSS2, a human transmembrane protease enzyme, plays a crucial role in the spread of certain viruses, including influenza and coronaviruses. This enzyme promotes viral infection by cleaving viral glycoproteins, which helps viruses like SARS-CoV-2 and ...
Gilmara Barros de Lima, Everton Nencioni, Fábio Thimoteo, Camila Perea, Rafaela Fuzaro Alves Pinto, Sergio Daishi Sasaki   +5 more
doaj   +1 more source

Proteinase inhibitors in Brazilian leguminosae

Memorias do Instituto Oswaldo Cruz, 1991
Serine proteinase inhitors, in the seeds of several Leguminosae from the Pantanal region (West Brazil), were studied using bovine trypsin, a digestive enzyme, Factor XIIa and human plasma Kallikrein, two blood clotting factors.
C. A. M. Sampaio, M. L. V. Oliva, A. S. Tanaka, M. U. Sampaio   +3 more
doaj   +1 more source

Purification and Characterization of a Novel Kazal-Type Trypsin Inhibitor from the Leech of Hirudinaria manillensis

Toxins, 2016
Kazal-type serine proteinase inhibitors are found in a large number of living organisms and play crucial roles in various biological and physiological processes.
Yanmei Lai, Bowen Li, Weihui Liu, Gan Wang, Canwei Du, Rose Ombati, Ren Lai, Chengbo Long, Hongyuan Li   +8 more
doaj   +1 more source

The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming

Toxins, 2021
A global strategy, under the coordination of the World Health Organization, is being unfolded to reduce the impact of snakebite envenoming. One of the pillars of this strategy is to ensure safe and effective treatments.
José María Gutiérrez, Laura-Oana Albulescu, Rachel H. Clare, Nicholas R. Casewell, Tarek Mohamed Abd El-Aziz, Teresa Escalante, Alexandra Rucavado   +6 more
doaj   +1 more source

The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]

, 2010
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page, Bernard, Blaxter, Chu, Cook, Fessler, Ford, Frand, Ghedin, Gillian McCormack, Gillian Stepek, Hawdon, Johnstone, Johnstone, Kingston, Kingston, Kramerova, Kramerova, Kress, Mieszczanek, Milstone, Nagano, Novelli, Novelli, Paesen, Page, Page, Poole, Priess, Redmond, Rhoads, Sasaki, Scott, Shamansky, Skuce, Stanssens, Studier, Thacker, Thacker, Thacker, Thacker, Thein, Wells, Winter   +43 more
core   +1 more source