Results 21 to 30 of about 754,866 (196)
Protein inhibitors of serine proteinases.
Serine proteinases and their natural protein inhibitors belong to the most intensively studied models of protein-protein recognition. Protein inhibitors do not form a single group but can be divided into about 20 different families. Global structures of proteins representing different inhibitor families are completely different and comprise alpha ...
J, Otlewski, D, Krowarsch, W, Apostoluk
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Proteinase activity in the midgut of the pentatomid stinkbug Podisus maculiventris was investigated. The optimal pH for adult and nymph proteolysis was pH 6.0 and pH 6.5, respectively.
Howard A. BELL +4 more
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Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases
Coronavirus disease 2019 (COVID-19) can lead to multi-organ failure influenced by comorbidities and age. Binding of the severe acute respiratory syndrome coronavirus 2 spike protein (SARS-CoV-2 S protein) to angiotensin-converting enzyme 2 (ACE2), along ...
Akmaral Assylbekova +5 more
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Analysis of serine proteinase–inhibitor interaction by alanine shaving [PDF]
AbstractWe analyzed the energetic importance of residues surrounding the hot spot (the P1 position) of bovine pancreatic trypsin inhibitor (BPTI) in interaction with two proteinases, trypsin and chymotrypsin, by a procedure called molecular shaving.
Olga, Buczek +4 more
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TRANSGENIC PLANTS RESISTANT TO INSECTS [PDF]
Proteinase inhibitors are secondary metabolites present in all plants and it seems that their major role is protection of plants against attacks of animals, insects and microorganisms.
S. Kereša +4 more
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Plasmin Inhibitors Prevent Leukocyte Accumulation and Remodeling Events in the Postischemic Microvasculature [PDF]
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear.
Nina Berberich +33 more
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Characterization of plasmin, plasminogen and plasminogen activator in goat milk
Plasmin (PL), a serine-proteinase, appears to be the predominant native proteinase in milk and it is mainly associated to casein micelles which represent its substrate (Bastian and Brown, 1996). Plasmin occurs in milk together with its inactive zymogene,
F. Polidori +3 more
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Identification and purification of a novel serine proteinase inhibitor
We report the identification, purification, and partial amino acid sequence of a novel serine proteinase inhibitor which is present in extracts from human placentas and in the cytosolic fraction of the leukemic cell line K562. Extracts from these tissues exhibited time-dependent inhibition of the serine proteinase thrombin.
P B, Coughlin, T, Tetaz, H H, Salem
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Midgut serine proteinases and alternative host plant utilization in Pieris brassicae L.
Pieris brassicae L. is a serious pest of cultivated crucifers in several parts of theworld. Larvae of P. brassicae also feed prolifically on garden nasturtium (Tropaeolummajus L., of the family Tropaeolaceae).
Rakesh eKumar +5 more
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Serine proteinases have been recognized as playing an important role in inflammation via proteinase activated receptors (PARs). However, little is known about the influence of serine proteinases and PARs on TNF secretion from highly purified T cells.
Haiwei Yang +4 more
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