Results 21 to 30 of about 37,649 (300)

Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases

Pharmaceuticals, 2022
Coronavirus disease 2019 (COVID-19) can lead to multi-organ failure influenced by comorbidities and age. Binding of the severe acute respiratory syndrome coronavirus 2 spike protein (SARS-CoV-2 S protein) to angiotensin-converting enzyme 2 (ACE2), along ...
Akmaral Assylbekova, Anuar Zhanapiya, Renata Grzywa, Marcin Sienczyk, Christian Schönbach, Timo Burster   +5 more
doaj   +1 more source

Analysis of serine proteinase–inhibitor interaction by alanine shaving [PDF]

Protein Science, 2002
AbstractWe analyzed the energetic importance of residues surrounding the hot spot (the P1 position) of bovine pancreatic trypsin inhibitor (BPTI) in interaction with two proteinases, trypsin and chymotrypsin, by a procedure called molecular shaving.
Olga, Buczek, Katarzyna, Koscielska-Kasprzak, Daniel, Krowarsch, Michał, Dadlez, Jacek, Otlewski   +4 more
openaire   +2 more sources

T-SP1: a novel serine protease-like protein predominantly expressed in testis [PDF]

, 2008
Here, we describe a novel member in the group of membrane-anchored chymotrypsin (S1)-like serine proteases, namely testis serine protease 1 (T-SP1), as it is principally expressed in testis tissue.
Nerlich, Andreas, Profanter, Birgit, Geissler, Claudia, Neth, Peter, Sommerhoff, Christian P., Naegler, Dorit K., Jochum, Marianne   +6 more
core   +1 more source

Digestive proteolytic activity in the gut and salivary glands of the predatory bug Podisus maculiventris (Heteroptera: Pentatomidae); effect of proteinase inhibitors

European Journal of Entomology, 2005
Proteinase activity in the midgut of the pentatomid stinkbug Podisus maculiventris was investigated. The optimal pH for adult and nymph proteolysis was pH 6.0 and pH 6.5, respectively.
Howard A. BELL, Rachel E. DOWN, John P. EDWARDS, John A. GATEHOUSE, Angharad M.R. GATEHOUSE   +4 more
doaj   +1 more source

TRANSGENIC PLANTS RESISTANT TO INSECTS [PDF]

Poljoprivreda, 2009
Proteinase inhibitors are secondary metabolites present in all plants and it seems that their major role is protection of plants against attacks of animals, insects and microorganisms.
S. Kereša, F. Chiesa, F. de Amicis, M. Barić, S. Marchetti   +4 more
doaj  

Identification and purification of a novel serine proteinase inhibitor

Journal of Biological Chemistry, 1993
We report the identification, purification, and partial amino acid sequence of a novel serine proteinase inhibitor which is present in extracts from human placentas and in the cytosolic fraction of the leukemic cell line K562. Extracts from these tissues exhibited time-dependent inhibition of the serine proteinase thrombin.
P B, Coughlin, T, Tetaz, H H, Salem
openaire   +2 more sources

Plasmin Inhibitors Prevent Leukocyte Accumulation and Remodeling Events in the Postischemic Microvasculature [PDF]

, 2011
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear.
Nina Berberich, Rehberg, Markus, Wymann, Matthias P., Wymann, M. P., Uhl, B., Lerchenberger, Max, Uhl, Bernd, Berberich, Nina, Reichel, Christoph A., Bernd Uhl, Markus Rehberg, Matthias P. Wymann, Zahler, Stefan, Reichel, C. A., Uhl Bernd, Berberich Nina, Krombach Fritz, Lerchenberger, M., Stefan Zahler, Reichel Christoph A., Berberich, N., Fritz Krombach, Rehberg Markus, Zahler, S., Christoph A. Reichel, Krombach, Fritz, Max Lerchenberger, Krombach, F., Lerchenberger Max, Zahler Stefan, Matthias P Wymann, Rehberg, M., Christoph A Reichel, Wymann Matthias P.   +33 more
core   +1 more source

Characterization of plasmin, plasminogen and plasminogen activator in goat milk

Italian Journal of Animal Science, 2011
Plasmin (PL), a serine-proteinase, appears to be the predominant native proteinase in milk and it is mainly associated to casein micelles which represent its substrate (Bastian and Brown, 1996). Plasmin occurs in milk together with its inactive zymogene,
F. Polidori, G. Lebbroni, P. Polidori, F. Fantuz   +3 more
doaj   +1 more source

Midgut serine proteinases and alternative host plant utilization in Pieris brassicae L.

Frontiers in Physiology, 2015
Pieris brassicae L. is a serious pest of cultivated crucifers in several parts of theworld. Larvae of P. brassicae also feed prolifically on garden nasturtium (Tropaeolummajus L., of the family Tropaeolaceae).
Rakesh eKumar, Rakesh eKumar, Usha eBhardwaj, Usha eBhardwaj, Pawan eKumar, Sudeshna eMazumdar-Leighton   +5 more
doaj   +1 more source

The effects of serine proteinase inhibitors on bone resorption in vitro [PDF]

Journal of Endocrinology, 2003
The aims of this study were to identify the role and sites of action of serine proteinases (SPs) in bone resorption, a process which involves a cascade of events, the central step of which is the removal of bone matrix by osteoclasts (OCs). This resorbing activity, however, is also determined by recruitment of new OCs to future resorption sites and ...
Tumber, A, Papaioannou, S, Breckon, J, Meikle, M C, Reynolds, J J, Hill, P A   +5 more
openaire   +3 more sources