Results 41 to 50 of about 128,354 (367)

Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors.

open access: yesEuropean Journal of Biochemistry, 1990
Prostate-specific antigen (PSA) is one of the three most abundant prostatic-secreted proteins in human semen. It is a serine proteinase that, in its primary structure, manifests extensive similarities with that of the Arg-restricted glandular kallikrein ...
A. Christensson, C. Laurell, H. Lilja
semanticscholar   +1 more source

Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases

open access: yesPharmaceuticals, 2022
Coronavirus disease 2019 (COVID-19) can lead to multi-organ failure influenced by comorbidities and age. Binding of the severe acute respiratory syndrome coronavirus 2 spike protein (SARS-CoV-2 S protein) to angiotensin-converting enzyme 2 (ACE2), along ...
Akmaral Assylbekova   +5 more
doaj   +1 more source

Paradigm of biased PAR1 (protease-activated receptor-1) activation and inhibition in endothelial cells dissected by phosphoproteomics [PDF]

open access: yes, 2017
Thrombin is the key serine protease of the coagulation cascade and mediates cellular responses by activation of PARs (protease-activated receptors). The predominant thrombin receptor is PAR1, and in endothelial cells (ECs), thrombin dynamically regulates
Hoogendijk, Arie J.   +7 more
core   +2 more sources

Digestive proteolytic activity in the gut and salivary glands of the predatory bug Podisus maculiventris (Heteroptera: Pentatomidae); effect of proteinase inhibitors

open access: yesEuropean Journal of Entomology, 2005
Proteinase activity in the midgut of the pentatomid stinkbug Podisus maculiventris was investigated. The optimal pH for adult and nymph proteolysis was pH 6.0 and pH 6.5, respectively.
Howard A. BELL   +4 more
doaj   +1 more source

Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp. [PDF]

open access: yes, 2010
The secretion of proteolytic enzymes by pathogenic microorganisms is one of the most successful strategies used by pathogens to colonize and infect the host organism.
Ben Nasr A.   +16 more
core   +1 more source

Vaccinia virus encodes a family of genes with homology to serine proteinase inhibitors.

open access: yesJournal of General Virology, 1989
Nucleotide sequencing of a region of the vaccinia virus genome proximal to the right inverted terminal repeat (ITR) identified two open reading frames (ORFs) encoding proteins of 39K and 40K with amino acid homology to each other, to another vaccinia ...
Geoffrey L. Smith   +2 more
semanticscholar   +1 more source

Identification and purification of a novel serine proteinase inhibitor

open access: yesJournal of Biological Chemistry, 1993
We report the identification, purification, and partial amino acid sequence of a novel serine proteinase inhibitor which is present in extracts from human placentas and in the cytosolic fraction of the leukemic cell line K562. Extracts from these tissues exhibited time-dependent inhibition of the serine proteinase thrombin.
Tim Tetaz   +2 more
openaire   +3 more sources

TRANSGENIC PLANTS RESISTANT TO INSECTS [PDF]

open access: yesPoljoprivreda, 2009
Proteinase inhibitors are secondary metabolites present in all plants and it seems that their major role is protection of plants against attacks of animals, insects and microorganisms.
S. Kereša   +4 more
doaj  

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

open access: yes, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY   +7 more
core   +3 more sources

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