Results 101 to 110 of about 234,379 (321)

SWS promoting MHb-IPN-MRN circuit opposes the theta promoting circuit, active wake and REM sleep [PDF]

arXiv, 2015
Hippocampus was by multisynaptic axonal tracts linked to medial habenula in my DTI study. These tracts linked hippocampus to septum, and amygdala to BNST. Septal and BNST axons passed by anteromedial thalamic nucleus to MHb, which projected to pineal gland.
arxiv  

Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Although dopamine transporter (DaT) imaging is a valuable diagnostic biomarker, few studies have investigated its utility in objectively monitoring disease progression in patients with Parkinson's disease (PD). To date, no study has established a longitudinal relationship between the DaT signal decline and the motor symptom increase ...
Verena Dzialas, Gérard N. Bischof, Kathrin Möllenhoff, Alexander Drzezga, Thilo van Eimeren   +4 more
wiley   +1 more source

Serotonin as a Creativity Pump [PDF]

arXiv
The location of Western Civilization defined nations in Europe and in the United States within the largest global pollen environments on the planet is proposed as a key factor leading to their success. Environments with dense pollen concentrations will cause large up and down changes in serum histamine directly causing reductions and increases in brain
arxiv  

Excited‐State Basicity Diverts the Site‐Selectivity of Aromatic Deuteration: Application to the Late‐Stage Labelling of Pharmaceuticals.

Angewandte Chemie International Edition, Accepted Article.
Isotope labelling, particularly with deuterium (2H), plays a critical role in drug discovery due to its ease of incorporation and its potential to switch unwanted metabolic transformations. Deuterium incorporation can enhance drug stability, affect pharmacokinetics, and alter metabolism pathways.
Eva Rivera-Chao, Javier Corpas, Giovanni Lonardi, Volker Derdau, Alessandro Ruffoni, Daniele Leonori   +5 more
wiley   +1 more source

Evaluating and forecasting the associated main flavor components in Baijiu (Chinese distilled spirits) with alcohol metabolism and hangover symptoms through mice acute withdrawal model

Food Science &Nutrition, Volume 11, Issue 1, Page 334-343, January 2023., 2023
Chinese distilled spirits (Baijiu) is one of the most favourite alcohol beverages. The flavor quality of Baijiu is supposed to be one of the key factors which caused the hangover. However, little systematic study has been done to estimate the flavors effects on the hangover in the different aroma‐type of Baijiu.
Jie Huangfu, Jun Lu, Changwen Li, Deliang Wang, Chunguang Luan, Xin Jiang, Tao Song, Wei Jiang, Xinlin Han, Jing Feng, Yanli Liu, Mengchao He   +11 more
wiley   +1 more source

Neuroeconomics of suicide [PDF]

Neuro Endocrinol Lett. 2011;32(4):400-404, 2011
Suicidal behavior is a leading cause of injury and death worldwide. Suicide has been associated with psychiatric illnesses such as depression and schizophrenia, as well as economic uncertainty, and social/cultural factors. This study proposes a neuroeconomic framework of suicide.
arxiv  

Nutritional and sensory properties of low‐fat milk dessert enriched with quinoa (Chenopodium quinoa Willd) Titicaca protein isolate

Food Science &Nutrition, Volume 11, Issue 1, Page 516-526, January 2023., 2023
The dessert containing 1% TQPI presented suitable physicochemical and sensory properties. The dessert containing 5% TQPI exhibited the highest values of texture parameters, protein content and WHC at 21st storage time. Abstract The purpose of this work was to investigate the potential production of Titicaca quinoa protein isolated (TQPI) to improve the
Seyed Saeed Sekhavatizadeh, Abdolhamid Karimi, Saeid Hosseinzadeh, Amir Reza Shaviklo, Mohsen Abedi, Hamidreza Mahmoodianfard, Mohsen Ghaedmohammadi   +6 more
wiley   +1 more source

Explainable Deep Learning Framework for SERS Bio-quantification [PDF]

arXiv
Surface-enhanced Raman spectroscopy (SERS) is a potential fast and inexpensive method of analyte quantification, which can be combined with deep learning to discover biomarker-disease relationships. This study aims to address present challenges of SERS through a novel SERS bio-quantification framework, including spectral processing, analyte ...
arxiv  

Toward molecular neuroeconomics of obesity [PDF]

arXiv, 2011
Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future study directions by unifying (i) economic theory of addiction and obesity (Becker and Murphy, 1988; Levy 2002 ...
arxiv  

Changes in Descending Pain Modulation During Anti–Tumor Necrosis Factor Therapy: A Prospective Study in Rheumatoid Arthritis and Spondyloarthritis

Arthritis &Rheumatology, EarlyView.
Objective In rheumatoid arthritis (RA) and spondyloarthritis (SpA), managing persistent pain remains challenging. Little is known regarding impaired pain pathways in these patients and the impact of biologic disease‐modifying antirheumatic drugs (bDMARDs).
Anne‐Priscille Trouvin, Arielle Simunek, Joël Coste, Terkia Medkour, Alice Combier, Lucile Poiroux, François Vidal, Sandrine Carvès, Didier Bouhassira, Serge Perrot   +9 more
wiley   +1 more source