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Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Bioassay-Guided Fractionation of <i>Annona macroprophyllata</i> Seeds to Evaluate Their Anxiolytic and Toxicological Effects. [PDF]

open access: yesMolecules
Murrieta-Dionicio U   +8 more
europepmc   +1 more source

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