Results 241 to 250 of about 709,580 (281)
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Triptans, Serotonin Agonists, and Serotonin Syndrome (Serotonin Toxicity): A Review
Headache: The Journal of Head and Face Pain, 2010( Headache 2010;50:264‐272) The US Food and Drug Administration (FDA) have suggested that fatal serotonin syndrome (SS) is possible with selective serotonin reuptake inhibitors (SSRIs) and triptans: this warning affects millions of patients as these drugs ...
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Relative Toxicity of Selective Serotonin Reuptake Inhibitors (SSRIs) in Overdose
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) have increasingly replaced tricyclic antidepressants (TCAs) in the treatment of depression. They appear to be safer in overdose, but there is little information on their spectrum of toxicity in ...
Ian Whyte +2 more
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Serotonin Syndrome: A Subtle Toxicity
Journal of Emergency Nursing, 2006Dana Bartlett is Poison Information Specialist, The Poison Control Center, The Children’s Hospital of Philadelphia, Philadelphia, Pa. For correspondence, write: Dana Bartlett, The Poison Control Center, The Children’s Hospital of Philadelphia, 34th St & Civic Center Blvd, Philadelphia, PA 19104; E-mail: bartlett@email.chop.edu. J Emerg Nurs 2006;32:277-
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Increased Toxicity of Serotonin in Adrenalectomized Animals
Nature, 1961ADRENALECTOMIZED rats and mice are more sensitive to anaphylactic shock1,2, and to the action of histamine3 and 5-hydroxytryptamine2,4 which may be involved in the anaphylactic reaction5, than are intact animals. The toxicity of histamine and of serotonin, as well as anaphylaxis, is increased by the administration of ‘pertussis vaccine’ and in old and ...
S, GARATTINI +3 more
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Carisoprodol poisoning with serotonin toxicity
BMJ Case ReportsDue to the implementation of stricter regulations in many countries, carisoprodol toxicity is an increasingly uncommon presentation to the emergency department. However, it remains a potential drug of abuse due to its low price, availability and ability to modulate GABA-A.
Conor Salmaan O’Flynn +2 more
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Management of serotonin syndrome (toxicity)
Serotonin syndrome (toxicity), resulting from an excessive accumulation of serotonin in the central nervous system, it can occur due to various factors such as the initiation of medication, overdose or drug interactions. Diagnosing serotonin toxicity presents challenges as there are no definitive criteria.
Angela Chiew, Geoffrey Isbister
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Perspectives on genetic animal models of serotonin toxicity
Neurochemistry International, 2008Serotonin syndrome, or serotonin toxicity, is a serious disorder attributable to exaggerated serotonergic function in the brain, most commonly after antidepressant overdose or after combining several psychotropic medications. Similar condition (serotonin syndrome-like behavior) can be evoked in animals experimentally, following administration of ...
Allan V Kalueff, Dennis L Murphy
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Olanzapine and serotonin toxicity
Psychiatry and Clinical Neurosciences, 2003Geoffrey K, Isbister +2 more
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Toxic Serotonin Syndrome or Neuroleptic Malignant Syndrome?
Pharmacopsychiatry, 2007Administration of medications which affect brain dopamine and serotonin levels are occasionally associated with neurotoxic behavioral and autonomic syndromes, variously described as the neuroleptic malignant (NMS) and the toxic serotonin (TSS) syndromes.
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