Partial Serotonin Transporter Deficiency Modulates Plasma Metabolome, Arginine-Nitric Oxide Pathway and Emotional Behavior in Mice Exposed to Western Diet. [PDF]
MetabolitesGorlova A +11 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu +2 more
wiley +1 more source
Cerebellar Abnormalities in the Neuroimaging Spectrum of CLTC‐Related Disorder
American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2601-2607, December 2026.ABSTRACT Pathogenic variants in CLTC, which encodes the clathrin heavy chain involved in vesicle‐mediated trafficking in neurons, cause a rare neurodevelopmental disorder associated with variable severity of global developmental delay and intellectual disability and structural brain abnormalities. Although corpus callosum and white matter anomalies are
Daniel Charouf +7 more
wiley +1 more source
Interaction of serotonin transporter and TGFB1 facilitates histone serotonylation-mediated synaptic plasticity following environmental enrichment in stressed mouse Mus booduga. [PDF]
Epigenetics ChromatinSowndharya S, Rajan KE.
europepmc +1 more source
An Anatomist's View on the Crosstalk Between the Liver and the Lung
Comprehensive Physiology, Volume 16, Issue 6, December 2026.The liver and the lung have a similar three‐dimensional and cellular architecture as well as functional communalities. The structural, functional, and pathophysiological interplay between both organs suggests the existence of an interorgan axis, the liver‐lung axis. Created in biorender.com.
Tanja Kloock +2 more
wiley +1 more source
Molecular Effect of Variants in Serotonin Transporter Gene in Women with Alcohol Use Disorder. [PDF]
CellsRychel M +7 more
europepmc +1 more source
The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 10, Page 977-992, December 2026.Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario +3 more
wiley +1 more source
More and Less Fear in Serotonin Transporter Knockout Mice. [PDF]
Genes Brain BehavLima J +4 more
europepmc +1 more source
Mucuna pruriens as a Sustainable Functional Food: Applications From Seed to Product
Modern Agriculture, Volume 4, Issue 2, December 2026.This review highlights Mucuna pruriens as a nutrient‐rich legume with significant nutritional, therapeutic, and agricultural value. Its protein‐rich seeds contain essential minerals and L‐DOPA, but high antinutritional compounds require effective processing before consumption.
Crossby Osei Tutu +10 more
wiley +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.Abstract Centanafadine is a multimodal norepinephrine–dopamine–serotonin reuptake inhibitor (NDSRI) that has been evaluated for the treatment of attention‐deficit/hyperactivity disorder (ADHD) across pediatric, adolescent, and adult populations. This systematic review aimed to evaluate the efficacy, safety, and tolerability of centanafadine compared ...
Daud Gul +12 more
wiley +1 more source