Results 21 to 30 of about 20,613 (283)
Serpins in Tick Physiology and Tick-Host Interaction
Frontiers in Cellular and Infection Microbiology, 2022 Tick saliva has been extensively studied in the context of tick-host interactions because it is involved in host homeostasis modulation and microbial pathogen transmission to the host.
Muhammad Nadeem Abbas +6 more
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Rhipicephalus microplus serine protease inhibitor family: annotation, expression and functional characterisation assessment [PDF]
Parasites & Vectors, 2015 Background Rhipicephalus (Boophilus) microplus evades the host’s haemostatic system through a complex protein array secreted into tick saliva. Serine protease inhibitors (serpins) conform an important component of saliva which are represented by a large ...
Manuel Rodriguez-Valle +3 more
doaj +9 more sources
Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics [PDF]
BMC OphthalmologyBackground Alterations in the constituents of the aqueous humor (AH) are associated with various ocular pathologies, including primary open-angle glaucoma (POAG).
Eliza Williams +11 more
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Serpins in the Spotlight: Novel Bioinformatic Insights Into Hyalomma dromedarii Sialotranscriptome [PDF]
Biochemistry Research InternationalTicks pose a significant global threat to human and animal health as vectors of numerous pathogens, including bacteria, viruses, and parasites. Beyond their harmful impact, tick salivary glands contain serine protease inhibitors (serpins) known for their
Hajer Aounallah +4 more
doaj +2 more sources
G3: Genes, Genomes, Genetics, 2019 The serine protease inhibitor (serpin) gene family is the largest family of protease inhibitors. Serine protease inhibitors have an active, but under-characterized, role in grain development and defense against pathogen attack in cereal crops.
Harriet R. Benbow +2 more
doaj +2 more sources
The roles of serine protease inhibitors in dermatoses [PDF]
Frontiers in GeneticsThe balance between proteases and their inhibitors is essential for maintaining the structural and functional homeostasis of the skin. Numerous studies have shown that serine protease inhibitors are highly expressed in the skin and play diverse roles in ...
Zhenzhen Xiao +5 more
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Regulation of epidermal barrier function and pathogenesis of psoriasis by serine protease inhibitors [PDF]
Frontiers in ImmunologySerine protease inhibitors (Serpins) are a protein superfamily of protease inhibitors that are thought to play a role in the regulation of inflammation, immunity, tumorigenesis, coagulation, blood pressure and cancer metastasis.
Juanjuan Wang +9 more
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Parasitoid Serpins Evolve Novel Functions to Manipulate Host Homeostasis [PDF]
Molecular biology and evolution, 2023 Parasitoids introduce various virulence factors when parasitism occurs, and some taxa generate teratocytes to manipulate the host immune system and metabolic homeostasis for the survival and development of their progeny.
Zhiwei Wu +9 more
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Serpins in arthropod biology [PDF]
Seminars in Cell & Developmental Biology, 2017 Serpins are the largest known family of serine proteinase inhibitors and perform a variety of physiological functions in arthropods. Herein, we review the field of serpins in arthropod biology, providing an overview of current knowledge and topics of interest.
David A, Meekins +2 more
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2017 The publication of the first tick sialome (salivary gland transcriptome) heralded a new era of research of tick protease inhibitors, which represent important constituents of the proteins secreted via tick saliva into the host.
Jindřich Chmelař +5 more
doaj +2 more sources