Results 31 to 40 of about 3,688,287 (401)
Severe asthma features in children: A case-control online survey [PDF]
, 2016 Background: Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe.
Aralla, R +18 more
core +3 more sources
BMC Pulmonary Medicine, 2021 Background Benralizumab, a monoclonal antibody targeting the human interleukin-5 (IL-5) receptor (IL-5R), was used before marketing authorisation in Spain in a real world setting as part of an early-access programme (EAP) to treat patients with severe ...
Eva Martínez-Moragón +4 more
doaj +1 more source
Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]
, 2012 Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose, Markus A. +5 more
core +2 more sources
Biologics and global burden of asthma: A worldwide portrait and a call for action
World Allergy Organization Journal, 2021 Biologics for severe asthma can significantly impact on the burden of disease and also have the potential to reduce asthma mortality. By reviewing the literature and contacting the pharmaceutical companies, the present paper aims at providing a worldwide
M. Caminati +6 more
doaj +1 more source
Does asthma impair wealth accumulation or does wealth protect against asthma? [PDF]
, 2016 OBJECTIVE: We investigate the association between adult asthma and wealth, testing whether the disease impairs wealth accumulation (social selection model) or if wealth protects against asthma (social causation model).
Smith, Patricia K., Zagorsky, Jay L.
core +1 more source
Depiction of Major Mite Allergens in Severe Allergic Rhinitis with High Mite Perennial Exposure
Turkish Archives of Otorhinolaryngology, 2020 Objective: Airway diseases, including allergic rhinitis, are prompted by specific IgE antibodies against airborne allergens and notably those derived from mites.
Ruperto González-Pérez +3 more
doaj +1 more source
Critical evaluation of asthma biomarkers in clinical practice
Frontiers in Medicine, 2022 The advent of personalized medicine has revolutionized the whole approach to the management of asthma, representing the essential basis for future developments.
Giuseppe Guida +14 more
doaj +1 more source
Efficacy and Safety of Dupilumab in Glucocorticoid‐Dependent Severe Asthma
New England Journal of Medicine, 2018 BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. Its effectiveness in reducing oral glucocorticoid use in patients with severe asthma while maintaining ...
K. Rabe +20 more
semanticscholar +1 more source
Feasibility of Discontinuing Biologics in Severe Asthma: An Algorithmic Approach
Journal of Asthma and Allergy, 2021 In severe asthma with type 2 (T2) inflammation, biologics targeting key mediators of T2 inflammation, including interleukin (IL)-5, IL-4/IL-13, and immunoglobulin (Ig)E, remarkably improve the management of severe asthma, providing new insights into the ...
K. Hamada +4 more
semanticscholar +1 more source
Biological therapy for severe asthma
Asthma Research and Practice, 2021 Around 5–10% of the total asthmatic population suffer from severe or uncontrolled asthma, which is associated with increased mortality and hospitalization, increased health care burden and worse quality of life. In the last few years, new drugs have been
S. Dragonieri, G. E. Carpagnano
semanticscholar +1 more source