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Severity of chronic asthma [PDF]
Thorax, 1998 How is the severity of chronic asthma best assessed and what are the mechanisms that determine its severity? These two questions are difficult to answer because, until we understand what asthma is, it is not possible to describe its severity in a given individual.
Daniel Dusser +2 more
openaire +3 more sources
Severe asthma and asthma control in schoolchildren [PDF]
, 2013 Background: Asthma is a major health problem in children and most troublesome during severe or persistent symptoms. Children with problematic severe asthma have a disproportionate consumption of health care, despite high-dose treatment with inhaled ...
Nordlund, Björn
core +1 more source
Allergology International, 2019 Obesity is an important global health issue for both children and adults. Obesity increases the prevalence and incidence of asthma and also increases the risk for severe asthma. Here we describe the features of severe asthma phenotypes for which obesity is a defining characteristic, including steroid resistance, airway inflammation, and co-morbidities.
Hiroki Tashiro, Stephanie A. Shore
openaire +4 more sources
Annals of MedicineBackground Some patients with severe asthma may benefit from treatment with biologics, but evidence has been mostly collected from randomized controlled trials (RCTs), in which patients’ characteristics are different from those encountered in asthma ...
Maria Basagaña +12 more
doaj +1 more source
Pathophysiology of severe asthma [PDF]
Journal of Allergy and Clinical Immunology, 2000 Although asthma affects nearly 8% of the adult population, most of these patients have mild-to-moderate disease that can be controlled with appropriate treatment. It is estimated, however, that 5% to 10% of patients with asthma have severe disease that is unresponsive to typical therapeutics, including corticosteroids.
William W. Busse +2 more
openaire +3 more sources
Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]
, 2018 BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E +3 more
core +1 more source
Asthma control in severe asthma and occupational exposures to inhalable asthmagens
BMJ Open Respiratory ResearchIntroduction Work-related asthma accounts for ≥25% of asthma in working-age populations, though the relationship between work exposures and symptoms is frequently missed, leading to poor health and employment outcomes.
Mamidipudi Thirumala Krishna +8 more
doaj +1 more source
Journal of Asthma and Allergy, 2020 Rationale Results from clinical trials in patients with severe eosinophilic asthma have demonstrated that mepolizumab is well tolerated and is associated with improved asthma control as evidenced by reductions in both exacerbations and maintenance oral ...
J. Llanos +6 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This research utilizes selective reduction laser sintering (SRLS) to engineer In2O3 NPs for flexible NO2 sensors. The introduction of oxygen vacancy defects enhances sensor performance, offering excellent responsiveness, rapid response/recovery, superior selectivity, low detection limit, and long‐term stability.
Shaogang Wang +8 more
wiley +1 more source