Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID) [PDF]
Frontiers in Pediatrics, 2019 Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell ...
Elie Haddad, Manfred Hoenig
doaj +7 more sources
A high-quality severe combined immunodeficiency (SCID) rat bioresource. [PDF]
PLoS ONE, 2022 Immunodeficient animals are valuable models for the engraftment of exogenous tissues; they are widely used in many fields, including the creation of humanized animal models, as well as regenerative medicine and oncology.
Yoshiki Miyasaka +7 more
doaj +5 more sources
Universal Newborn Screening for Severe Combined Immunodeficiency (SCID) [PDF]
Frontiers in Pediatrics, 2019 Patients with severe combined immunodeficiency (SCID) are born with profound deficiency of functional T-lymphocytes. Early detection and diagnosis would allow for prompt institution of isolation from infection and referral for definitive treatment with ...
Mirjam van der Burg +5 more
doaj +9 more sources
Severe Combined Immunodeficiency (SCID) and Its New Treatment Modalities. [PDF]
Cureus, 2023 Severe combined immunodeficiency (SCID) is a rare condition with very high mortality. SCID is mainly caused by the multiple mutations of genes affecting the entire immune cells. Children with this disease are born with an impaired immune system.
Wadbudhe AM, Meshram RJ, Tidke SC.
europepmc +4 more sources
Introducing Newborn Screening for Severe Combined Immunodeficiency (SCID) in the Dutch Neonatal Screening Program. [PDF]
Int J Neonatal Screen, 2018 The implementation of newborn screening for severe combined immunodeficiency (SCID) in the Netherlands is a multifaceted process in which several parties are involved. The Dutch Ministry of Health adopted the advice of the Dutch Health Council to include
Blom M +8 more
europepmc +4 more sources
Review of Treatment for Adenosine Deaminase Deficiency (ADA) Severe Combined Immunodeficiency (SCID) [PDF]
Therapeutics and Clinical Risk Management, 2022 Elizabeth Secord,1 Nicholas L Hartog2 1Pediatrics, Division of Allergy and Immunology, Wayne State University School of Medicine, Detroit, MI, USA; 2Pediatrics, Division of Allergy and Immunology, Michigan State University College of Human Medicine ...
Secord E, Hartog NL
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Zebrafish Model of Severe Combined Immunodeficiency (SCID) Due to JAK3 Mutation [PDF]
Biomolecules, 2022 JAK3 is principally activated by members of the interleukin-2 receptor family and plays an essential role in lymphoid development, with inactivating JAK3 mutations causing autosomal-recessive severe combined immunodeficiency (SCID).
Faiza Basheer +3 more
doaj +4 more sources
Clinical, Immunological, and Molecular Findings in 57 Patients With Severe Combined Immunodeficiency (SCID) From India. [PDF]
Front Immunol, 2019 Severe combined immunodeficiency (SCID) represents one of the most severe forms of primary immunodeficiency (PID) disorders characterized by impaired cellular and humoral immune responses.
Aluri J +18 more
europepmc +2 more sources
NK cell function in severe combined immunodeficiency (SCID): evidence of a common T and NK cell defect in some but not all SCID patients. [PDF]
Journal of Immunology, 1983 The immunologic work-up of eight infants with the clinical diagnosis of severe combined immunodeficiency (SCID) was performed with special emphasis on natural killer (NK) cell function and ontogeny.
H. H. Peter +7 more
openalex +2 more sources
The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions. [PDF]
J Allergy Clin Immunol, 2023 Dvorak CC +18 more
europepmc +2 more sources