Abstract figure legend AII amacrine cells are an important class of interneuron in the vertebrate retina. In addition to traditional chemical synapses these cells communicate with other neurons and with each other via electrical synapses. (A) Electrical synapse strength between AII amacrine cells was measured using dual whole‐cell patch‐clamp ...
Chloe Cable +2 more
wiley +1 more source
The European internet-based patient and research database for primary immunodeficiencies: results 2006-2008 [PDF]
Primary immunodeficiencies (PID) are rare diseases; therefore transnational studies are essential to maximize the scientific outcome and to improve diagnosis and therapy.
Abuzakouk M. +70 more
core +1 more source
Specificity in V(D)J recombination: new lessons from biochemistry and genetics [PDF]
Recent in vitro work on V(D)J recombination has helped to clarify its mechanism. The first stage of the reaction, which can be reproduced with the purified RAG1 and RAG2 proteins, is a site-specific cleavage that generates the same ...
Gellert, M. +2 more
core +3 more sources
Thymus transplantation for complete DiGeorge syndrome: European experience [PDF]
Background: Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). Methods: Twelve patients with cDGS were transplanted with allogeneic cultured thymus.
Adrian J. Thrasher +59 more
core +3 more sources
Data in support of the bone analysis of NOD–SCID mice treated with zoledronic acid and prednisolone
This paper reports data on the bone, specifically the tibia and mandible, of nonobese diabetic mice with severe combined immunodeficiency disease (NOD–SCID mice) treated with zoledronic acid (ZA) and prednisolone (PSL).
Naoko Hori +6 more
doaj +1 more source
Disseminated tuberculosis complicating Bacillus Calmette-Guérin (BCG) vaccine as only presentation of severe combined immunodeficiency (SCID): A report of 3 cases. [PDF]
Omer K, Algaly G, Mohamed Salih OA.
europepmc +1 more source
Severe combined immunodeficiency (SCID): a case series from a paediatric hospital in Kenya
Rohini Kalagouda Patil +6 more
openalex +1 more source
A Review of Primary Immune Deficiency Disorders
This scenario-based review of primary immunodeficiency diseases (PIDD) discusses the differential diagnosis, usual presentations, work-up, and treatment of children with the most commonly encountered immune disorders.
Talin Darian +4 more
doaj
Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse. [PDF]
Infection with the human immunodeficiency virus (HIV) results in immunosuppression and depletion of circulating CD4+ T cells. Since the thymus is the primary organ in which T cells mature it is of interest to examine the effects of HIV infection in this ...
Adelsberger, J +9 more
core
Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches [PDF]
Xenotransplantation of patient-derived samples in mouse models has been instrumental in depicting the role of hematopoietic stem and progenitor cells in the establishment as well as progression of hematological malignancies.
Abarrategi, A +5 more
core +1 more source

