Results 21 to 30 of about 1,917,601 (292)
Benralizumab, an add-on treatment for severe eosinophilic asthma: evaluation of exacerbations, emergency department visits, lung function, and oral corticosteroid use
Therapeutics and Clinical Risk Management, 2018 Diego Jose Maselli,1 Linda Rogers,2 Jay I Peters1 1Division of Pulmonary Diseases and Critical Care, University of Texas Health, San Antonio, TX, USA; 2Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine Mount Sinai &ndash ...Maselli DJ, Rogers L, Peters JIdoaj +1 more sourceResponse to benralizumab in patients with severe eosinophilic asthma. [PDF]
Rev Med Inst Mex Seguro SocAbstract Background: Severe asthma represents a significant public health challenge, and monoclonal antibodies such as benralizumab represent an effective therapeutic option for achieving disease control. Objective: To evaluate the effectiveness of benralizumab in patients with severe eosinophilic asthma by assessing changes in fractional exhaled ...Velasco-Santos JI, Núñez-Martínez FJ, Martínez-Sánchez BH, Chávez-Lárraga AJ. +3 moreeuropepmc +3 more sourcesPrevalence of eosinophilic, atopic, and overlap phenotypes among patients with severe asthma in Saudi Arabia: a cross-sectional study
BMC Pulmonary Medicine, 2022 Background Eosinophilia is a significant factor in asthma severity; however, the prevalence of severe eosinophilic asthma in Saudi Arabia is largely unknown.Hamdan Al-Jahdali, Siraj Wali, Amr S. Albanna, Riyad Allehebi, Hussein Al-Matar, Mohamed Fattouh, Maarten Beekman +6 moredoaj +1 more sourceSevere asthma: adding new evidence – Latin American Thoracic Society
ERJ Open Research, 2021 This document constitutes a summary of the clinical practice guidelines (CPGs) prepared at the initiative of the Latin American Thoracic Society (ALAT). Due to new evidence in the treatment of severe asthma, it was agreed to select six clinical questions,Gabriel García, Miguel Bergna, Juan C. Vásquez, Maria C. Cano Salas, José L. Miguel, Carlos Celis Preciado, Agustin Acuña Izcaray, Manuel Barros Monge, Natalia García Batista, Ignacio Zabert, José L. Mayorga, Renato Casanova Mendoza, Martha Gutierrez, Maria F. Montero Arias, Luzcenelia Urtecho Perez, Miguel Antúnez, Victoria Williams Derby, Alejandra Villatoro Azméquita, Luis Motiño, M. Alenita De Oliveira, Diana Rey Sanchez, Marisol Arroyo, Mario Rodriguez +22 moredoaj +1 more sourceSuccessful treatment with dupilumab for mucus plugs in severe asthma
Respirology Case Reports, 2023 A 29‐year‐old man presented to our hospital with severe eosinophilic asthma. He needed a short OCS burst for exacerbation of asthma once every 1 or 2 months, although he used a high dose of inhaled corticosteroids and a long‐acting beta‐2 agonists. Chest Moriyasu Anai, Chieko Yoshida, Hiroki Izumi, Kei Muramoto, Koichi Saruwatari, Yusuke Tomita, Hidenori Ichiyasu, Takuro Sakagami +7 moredoaj +1 more sourcePersonalized and Precision Medicine in Asthma and Eosinophilic Esophagitis: The Role of T2 Target Therapy
Pharmaceutics, 2023 The role of type 2 inflammation has been progressively associated with many diseases, including severe asthma, atopic dermatitis, nasal polyposis, eosinophilic granulomatosis with polyangiitis, and, recently, eosinophilic esophagitis.Diego Bagnasco, Edoardo Vincenzo Savarino, Mona-Rita Yacoub, Fulvio Braido, Maria Giulia Candeliere, Edoardo Giannini, Giovanni Passalacqua, Elisa Marabotto +7 moredoaj +1 more sourceTargeting eosinophils: severe asthma and beyond [PDF]
Drugs in Context, 2019 Recent research in the field of bronchial asthma has mainly focused on eosinophilic disease phenotype. Several trials proved the efficacy and safety profile of eosinophils and interleukin (IL)-5 targeting molecules, currently approved for severe asthma and available on the market.Caminati, Marco, Menzella, Francesco, Guidolin, Lucia, Senna, Gianenrico +3 moreopenaire +5 more sourcesIdentification of distinct phenotypes related to benralizumab responsiveness in patients with severe eosinophilic asthma.
PLoS ONE, 2021 PurposeTo characterize the clinical phenotypes of severe eosinophilic asthma based on early responsiveness to benralizumab in terms of forced expiratory volume in 1 second (FEV1) improvement.Patients and methodsSixty-four participants diagnosed with ...Hideyasu Yamada, Masayuki Nakajima, Masashi Matsuyama, Yuko Morishima, Naoki Arai, Norihito Hida, Taisuke Nakaizumi, Hironori Masuko, Yohei Yatagai, Takefumi Saito, Nobuyuki Hizawa +10 moredoaj +1 more sourceEosinophilic and Noneosinophilic Asthma: An Expert Consensus Framework to Characterize Phenotypes in a Global Real-Life Severe Asthma Cohort [PDF]
, 2021 BACKGROUND: Phenotypic characteristics of eosinophilic and non-eosinophilic asthma patients are not well-characterized in global, real life severe asthma cohorts.RESEARCH QUESTION: What is the prevalence of eosinophilic and non-eosinophilic phenotypes in Taube, Christian, Tran, Trung N., Christoff, GC, Popov, TA, Lehtimäki, L, Alan Altraja, Victoria A. Carter, Brusselle, Guy G., Porsbjerg, CM, Costello, RW, Matthew Peters, Bjermer, Leif, Pfeffer, Paul, Jackson, David J, Takashi Iwanaga, Canonica, GW, Al-Ahmad, M, Paul E. Pfeffer, J. Mark FitzGerald, Iwanaga, T, Taillé, C, Busby, J, Carter, Victoria A., Vibeke Backer, Zangrilli, James, Papadopoulos, Nikolaos, FitzGerald, JM, Eleangovan, Neva, Eleangovan, Nevaashni, Tran, Trung N, Bourdin, Arnaud, Arnaud Bourdin, Price, DB, Papaioannou, Andriana, Christoff, George, Brusselle, Guy, Mark Hew, Lehmann, Sverre, Lehtimäki, Lauri, Papaioannou, Andriana I., Alacqua, M, Heaney, Liam G, Iwanaga, Takashi, Tohda, Yuji, Nikos G. Papadopoulos, Christian Taube, Rhee, Chin Kook, John Busby, Mohsen Sadatsafavi, Borja G. Cosio, Popov, Todor, Ruth Murray, Koh, Mariko Siyue, Buhl, Roland, Menzies-Gow, Andrew N, Popov, Todor A, Price, David B, Wang, E, Bulathsinhala, L, Zangrilli, J, Busby, John, Cosio, BG, Papaioannou, AI, Heaney, Liam G., Chaudhry, Isha, Trung N. Tran, Backer, Vibeke, Andriana I. Papaioannou, Camille Taillé, Jackson, David, Price, David B., Hosseini, Naeimeh, Heffler, E, Eleangovan, N, Heffler, Enrico, G. Walter Canonica, Cosio, Borja, Tohda, Y, Kerkhof, Marjan, Kerkhof, M, Papadopoulos, NG, Lakmini Bulathsinhala, Wang, Eileen, Yuji Tohda, Wechsler, ME, Altraja, Alan, Wechsler, Michael E, Luis Perez de Llano, Popov, Todor A., Enrico Heffler, Brusselle, Guy G, Sadatsafavi, M, Leif Bjermer, Pfeffer, Paul E, Chaudhry, I, Mona Al-Ahmad, Tran, Trung, Papadopoulos, Nikolaos G., Celeste M. Porsbjerg, Pfeffer, PE, Menzies-Gow, Andrew N., Murray, RB, Alacqua, Marianna, Siyue, MK, Murray, Ruth, Wechsler, Michael E., Papadopoulos, Nikolaos G, Isha Chaudhry, FitzGerald, J. Mark, Peters, M, Chin Kook Rhee, Price, Chris A., Siyue, Mariko Koh, Pfeffer, Paul E., David B. Price, Chris A. Price, Costello, Richard W, Hosseini, N, George C. Christoff, Altraja, A, Liam G. Heaney, Björnsdóttir, Unnur S, Taillé, Camille, Tran, TN, Lehmann, S, Porsbjerg, Celeste, Buhl, R, Heaney, Liam, Murray, Ruth B., Sadatsafavi, Mohsen, Roland Buhl, Eileen Wang, Christoff, George C., Björnsdóttir, Unnur, Backer, V, Perez de Llano, Luis, David J. Jackson, Mariko Siyue Koh, Christoff, George C, Hew, M, Hew, Mark, Björnsdóttir, Unnur S., Bourdin, A, Jackson, David J., Carter, Victoria, Al-Ahmad, Mona, Andrew N. Menzies-Gow, Porsbjerg, Celeste M., Jackson, DJ, Price, CA, Unnur S. Björnsdóttir, Price, Chris A, Brusselle, GG, Eileen, Wang, Heaney, LG, Naeimeh Hosseini, FitzGerald, J Mark, Canonica, Giorgio Walter, Cosio, Borja G, Marianna Alacqua, James Zangrilli, Cosio, Borja G., Costello, Richard, Menzies-Gow, AN, Costello, Richard W., Richard W. Costello, Papaioannou, Andriana I, Peters, Matthew, G.G.O. (Guy) Brusselle, Menzies-Gow, Andrew, Marjan Kerkhof, Wechsler, Michael, Carter, Victoria A, Murray, Ruth B, Price, Chris, Porsbjerg, Celeste M, Bulathsinhala, Lakmini, Michael E. Wechsler, Sverre Lehmann, Björnsdóttir, US, Lauri Lehtimäki, Bjermer, L, Price, David, Neva Eleangovan, Rhee, CK, Perez de Llano, L, Taube, C, Todor A. Popov, Carter, VA, Kerkhof, Marjan,, Pierachille Santus, Francesco Mazza, Lehmann, Sverre,, Vicente Plaza, Alacqua, Marianna,, Price, Chris A.,, Gianenrico Senna, Francesco Menzella, Paolo Montuschi, Linda Rasmussen, FitzGerald, J. Mark,, Ji yong Moon, Maria D’Amato, Soichiro Hozawa, Tran, Trung N.,, MariaElisabetta Conte, Eleonora Nucera, Pearlanne Zelarney, Murray, Ruth B.,, Désirée Larenas Linnemann, Iwanaga, Takashi,, Johannes Schmid, Bjermer, Leif,, Carlo Lombardi, Hew, Mark,, Salvatore Lo Cicero, Wang, Eileen,, Antonio Spanevello, Riyad Al-Lehebi, Lorenzo Cosmi, Vittorio Viviano, Giovanni Rolla, Manlio Milanese, Takahiko Horiguchi, Cvetanka Odjakova, Girolamo Pelaia, Piotr Kuna, Cristiano Caruso, Papaioannou, Andriana I.,, Menzies-Gow, Andrew N.,, Peters, Matthew,, Heffler, Enrico,, Sadatsafavi, Mohsen,, Stefano Centanni, Jasmina Nurkic, Costello, Richard W.,, Andreanne Cote, Joy Zimmer, Cosio, Borja G.,, Hosseini, Naeimeh,, Mohit Bhutani, Paolo Solidoro, Esther Garcia Gil, Kirsten Rasmussen, Koh, Mariko Siyue,, Giuseppe Spadaro, Gabriella Guarnieri, Eleangovan, Neva,, Pfeffer, Paul E.,, Nunzio Crimi, Hiroshi Tanaka, Cecilia Calabrese, Jae Ha Lee, Backer, Vibeke,, Wechsler, Michael E.,, Nadezda K. Takovska, Giovanni Passalacqua, Ahmed Maher, Laura Pini, Lehtimäki, Lauri,, Gianna Camiciottoli, Karin Dahl Assing, Angelo Guido Corsico, Christoff, George C.,, Price, David B.,, Concetta Sirena, Brusselle, Guy G.,, Dloui Philippe Boulet, Darina Petrova Dimova, Youlim Kim, Lund University., Taube, Christian,, Bassam Mahboub, Kwang Ha Yoo, Luisa Ricciardi, Elisabetta Favero, Al-Ahmad, Mona,, Carter, Victoria A.,, Caterina Bucca, Heaney, Liam G.,, Chaudhry, Isha,, Erminia Ridolo, Ole Hilberg, Konstantinos Kostikas, Canonica, Giorgio Walter,, Papadopoulos, Nikolaos G.,, Alessandro Farsi, Giannis Paraskevopoulos, Plamen Hristov Yakovliev, Maria Teresa Costantino, Charlotte Ulrik, Rupert C. Jones, Sundeep Salvi, Jorge Maspero, Sonya Metodieva Genova, Maria Cristina Zappa, Porsbjerg, Celeste M.,, Roberta Parente, Seung Won Ra, Price Chris A, Anders Christiansen, Luigi Macchia, Diahn-Warng Perng (Steve), Björnsdóttir, Unnur S.,, Zangrilli, James,, Maria Filomena Caiaffa, Taillé, Camille,, Louis Phillipe Boulet, Francesco Blasi, Nicola Scichilone, Carlos A. Torres-Duque, Giuseppe Guida, Buhl, Roland,, Perez de Llano, Luis,, Barbaro Maria Pia Foschino, Diana X. Hristova, Altraja, Alan,, Celine Bergeron, Busby, John,, Marcello Montagni, Pierluigi Paggiaro, Price David B, Kenneth Chapman, Simona D’Alò, Stefano Del Giacco, Bulathsinhala, Lakmini,, Peter G. Gibson, Eleonara M. Stamenova, Stelios Loukides, Daniela Morrone, Violina Milchova Vasileva, Bourdin, Arnaud,, Luca Richeldi, Marco Bonavia, Jackson, David J.,, Andrea Vianello, Fabio Luigi Massimo Ricciardolo, Mona-Rita Yacoub, VincenzoPatella, Katya Vasileva Noleva, Guy G. Brusselle, Nikolaos G. Papadopoulos, Ruth B. Murray, Giorgio Walter Canonica +343 morecore +1 more sourceUtility of serum periostin in combination with exhaled nitric oxide in the management of asthma
Allergology International, 2017 Type-2/eosinophilic inflammation plays a pivotal role in asthma. The identification of severe type-2/eosinophilic asthma is important for improving the management of patients with asthma.Tadao Nagasaki, Hisako Matsumoto, Kenji Izuhara, Yoshihiro Kanemitsu, Yuji Tohda, Takahiko Horiguchi, Hideo Kita, Keisuke Tomii, Masaki Fujimura, Akihito Yokoyama, Yasutaka Nakano, Soichiro Hozawa, Isao Ito, Tsuyoshi Oguma, Yumi Izuhara, Tomoko Tajiri, Toshiyuki Iwata, Tetsuji Yokoyama, Akio Niimi, Michiaki Mishima +19 moredoaj +1 more source
