Results 1 to 10 of about 24,858 (221)
The effect on shikimate production by deleting iolR and metabolic engineering in PTS deficient Corynebacterium glutamicum strain [PDF]
Frontiers in Bioengineering and BiotechnologyShikimate is a precursor to many high-value chemical derivatives. Several bacteria have been engineered to produce high titer of shikimate via non-phosphotransferase system (Non-PTS), but yet explores how the myo-inositol utilization transcription ...
Rui Wen Ou +8 more
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Engineering of Corynebacterium glutamicum for the synthesis of aromatic compounds [PDF]
Applied Microbiology and BiotechnologyA significant proportion of industrially important small molecules are aromatic, and the majority of these compounds are produced chemically, relying heavily on fossil resources.
Jan Marienhagen
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Multiple Metabolic Engineering Strategies to Improve Shikimate Titer in Escherichia coli
Metabolites, 2023 Shikimate is a valuable chiral precursor for synthesizing oseltamivir (Tamiflu®) and other chemicals. High production of shikimate via microbial fermentation has attracted increasing attention to overcome the unstable and expensive supply of shikimate ...
Taidong Bo +6 more
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Biophysica, 2021 The chemical step of Shikimate Kinase Helicobacter pylori, involving the transfer of a phosphoryl group, has been studied by using quantum mechanical and molecular mechanical (QM/MM) methods.
Pedro Ojeda-May
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Exploring the Dynamics of Shikimate Kinase through Molecular Mechanics
Biophysica, 2022 Shikimate kinase (SK) enzyme is a suitable target for antimicrobial drugs as it is present in pathogenic microorganisms and absent in mammals. A complete understanding of the functioning of this enzyme can unveil novel methods to inactivate it.
Pedro Ojeda-May
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Comparison of Sensitivity to Glyphosate of Euphorbia davidii Populations [PDF]
Planta Daninha, 2017 : Euphorbia davidii (Euphorbiaceae) is a summer annual weed present in the Province of Buenos Aires, Argentina. The aim of this study was to compare the sensitivity to glyphosate of different populations of Euphorbia davidii.
F.R. NÚÑEZ FRÉ +4 more
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Molecules, 2022 The shikimate pathway is a necessary pathway for the synthesis of aromatic compounds. The intermediate products of the shikimate pathway and its branching pathway have promising properties in many fields, especially in the pharmaceutical industry.
Sijia Wu +4 more
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Bioscience Journal, 2020 A sensitive and reliable process was established using high-performance liquid chromatography (HPLC) to distinguish conventional varieties of glyphosate-resistant genetically modified crops via shikimate detection in soybean (Glycine max L. Merril) seeds.
Edicléia Aparecida Bonini +4 more
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RETRACTED: Interaction of shikimic acid with shikimate kinase [PDF]
Biochemical and Biophysical Research Communications, 2004 Tuberculosis made a resurgence in the mid-1980s and now kills approximately 3 million people a year. The re-emergence of tuberculosis as a public health threat, the high susceptibility of HIV-infected persons and the proliferation of multi-drug-resistant strains have created a need to develop new drugs.
José Henrique Pereira +7 more
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Evaluation of the Mechanism Responsible for the Low-Level Resistance to Glyphosate in Goosegrass [PDF]
Planta Daninha, 2017 Goosegrass (Eleusine indica) infests various crops, being reported as low-level resistant (LLR) to glyphosate. The objectives of this study were to evaluate the mechanisms of resistance to glyphosate in goosegrass by the cyt-P450 complex to identify ...
A.R. ULGUIM +4 more
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