Results 31 to 40 of about 14,898 (199)

Genomic Analysis of Microbulbifer sp. Strain A4B-17 and the Characterization of Its Metabolic Pathways for 4-Hydroxybenzoic Acid Synthesis

open access: yesFrontiers in Microbiology, 2018
The marine bacterium Microbulbifer sp. A4B-17 produces secondary metabolites such as 4-hydroxybenzoic acid (4HBA) and esters of 4HBA (parabens). 4HBA is a useful material in the synthesis of the liquid crystal.
Jun Tian   +8 more
doaj   +1 more source

Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis. [PDF]

open access: yesPLoS ONE, 2014
Due to the emergence of resistance toward current antibiotics, there is a pressing need to develop the next generation of antibiotics as therapeutics against infectious and opportunistic diseases of microbial origins.
Vivian Wing Ngar Cheung   +7 more
doaj   +1 more source

Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production

open access: yesNature Communications, 2023
Plant-sourced aromatic amino acid (AAA) derivatives are a vast group of compounds with broad applications. Here, we present the development of a yeast consortium for efficient production of (S)-norcoclaurine, the key precursor for benzylisoquinoline ...
Meirong Gao   +5 more
doaj   +1 more source

Shikimate gene screening results.

open access: yes, 2022
Breadth of coverage at 3x depth across genes associated with the shikimate synthesis cluster in F. persica. Annotation was provided if a frameshift mutation was observed or if the gene appeared to be intact, all based on Snippy annotations. (XLSX)
Roxanne Nottingham (602105)   +14 more
core   +1 more source

The mode of action of recombinant Mycobacterium tuberculosis shikimate kinase: kinetics and thermodynamics analyses. [PDF]

open access: yesPLoS ONE, 2013
Tuberculosis remains as one of the main cause of mortality worldwide due to a single infectious agent, Mycobacterium tuberculosis. The aroK-encoded M.
Leonardo Astolfi Rosado   +6 more
doaj   +1 more source

Targeted modulation of the shikimate pathway enhances bacterial wilt resistance through NbMEE32 suppression in tobacco

open access: yesIndustrial Crops and Products
The shikimate pathway serves as a central metabolic route for the biosynthesis of aromatic amino acids and diverse secondary metabolites involved in plant growth and defense.
Dong Cheng   +7 more
doaj   +1 more source

Accumulation of Polyphenolics and Differential Expression of Genes Related to Shikimate Pathway during Fruit Development and Maturation of Chinese Olive (Canarium album)

open access: yesAgronomy, 2023
Phenolics in the Chinese olive (Canarium album (Lour.) Raeusch) fruit significantly affect its flavor and quality. The shikimate pathway is a bridge connecting primary metabolism and secondary metabolism through which fixed carbon can be transformed into
Jingrong Cai   +9 more
doaj   +1 more source

Pathway-based screening strategy for multitarget inhibitors of diverse proteins in metabolic pathways. [PDF]

open access: yesPLoS Computational Biology, 2013
Many virtual screening methods have been developed for identifying single-target inhibitors based on the strategy of "one-disease, one-target, one-drug".
Kai-Cheng Hsu   +4 more
doaj   +1 more source

Shikimate Kinase catalyzed phosphoryl transfer from ATP to C3 hydroxyl group of shikimate (SKH), yielding shikimate 3-phosphate (S3P) and ADP.

open access: yes, 2013
Shikimate Kinase catalyzed phosphoryl transfer from ATP to C3 hydroxyl group of shikimate (SKH), yielding shikimate 3-phosphate (S3P) and ADP.
Igor Bordin Vasconcelos (410085)   +6 more
core   +1 more source

Proteostatic Regulation of MEP and Shikimate Pathways by Redox-Activated Photosynthesis Signaling in Plants Exposed to Small Fungal Volatiles

open access: yesFrontiers in Plant Science, 2021
Microorganisms produce volatile compounds (VCs) with molecular masses of less than 300 Da that promote plant growth and photosynthesis. Recently, we have shown that small VCs of less than 45 Da other than CO2 are major determinants of plant responses to ...
Kinia Ameztoy   +15 more
doaj   +1 more source

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