Results 31 to 40 of about 15,124 (230)

Targeting Shikimate Kinase Pathway of Acinetobacter baumannii: A Structure-Based Computational Approach to Identify Antibacterial Compounds

open access: yesJournal of Tropical Medicine, 2023
Acinetobacter baumannii (A. baumannii) is an opportunistic bacterium that has developed multidrug resistance (MDR) to most of today’s antibiotics, posing a significant risk to human health.
Aparna Shil   +4 more
doaj   +1 more source

The three-dimensional structure of shikimate kinase [PDF]

open access: yes, 1998
The three-dimensional structure of shikimate kinase from Erwinia chrysanthemi has been determined by multiple isomorphous replacement. Two models are presented: a high resolution 1.9 Å model and a 2.6 Å model which contains bound Mg-ADP. The enzyme is an
Coggins, John R.   +2 more
core   +1 more source

Development of a co-culture system for green production of caffeic acid from sugarcane bagasse hydrolysate

open access: yesFrontiers in Microbiology
Caffeic acid (CA) is a phenolic acid compound widely used in pharmaceutical and food applications. However, the efficient synthesis of CA is usually limited by the resources of individual microbial platforms.
Xihui Wang   +14 more
doaj   +1 more source

Avaliação do uso de glyphosate em soja geneticamente modificada e sua relação com o ácido chiquímico Evaluation of glyphosate application on transgenic soybean and its relationship with shikimic acid

open access: yesPlanta Daninha, 2012
Com o aumento da comercialização de culturas geneticamente modificadas (GM) resistentes ao glyphosate, é importante investigar a relação entre o uso desse herbicida e seus efeitos no crescimento e desenvolvimento de plantas de soja GM, assim como sua ...
D.A.S. Franco   +6 more
doaj   +1 more source

Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis. [PDF]

open access: yesPLoS ONE, 2014
Due to the emergence of resistance toward current antibiotics, there is a pressing need to develop the next generation of antibiotics as therapeutics against infectious and opportunistic diseases of microbial origins.
Vivian Wing Ngar Cheung   +7 more
doaj   +1 more source

Biochemical research elucidating metabolic pathways in Pneumocystis*

open access: yesParasite, 2010
Advances in sequencing the Pneumocystis carinii genome have helped identify potential metabolic pathways operative in the organism. Also, data from characterizing the biochemical and physiological nature of these organisms now allow elucidation of ...
Kaneshiro E.S.
doaj   +1 more source

Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production

open access: yesNature Communications, 2023
Plant-sourced aromatic amino acid (AAA) derivatives are a vast group of compounds with broad applications. Here, we present the development of a yeast consortium for efficient production of (S)-norcoclaurine, the key precursor for benzylisoquinoline ...
Meirong Gao   +5 more
doaj   +1 more source

In situ monitoring of the Shikimate pathway: A combinatorial approach of Raman reverse stable isotope probing and hyperspectral imaging. [PDF]

open access: yes
Our research is focused on evaluating the potentials of Raman reverse stable isotope probing for sensing and visualizing the Shikimate pathway activity in prokaryotic and eukaryotic model systems in a cost-effective and non-destructive manner at ...
Aryan, Gupta   +2 more
core   +1 more source

Creation of a Shikimate Pathway Variant [PDF]

open access: yes, 2016
The competition between the Escherichia coli carbohydrate phosphotransferase system and 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthase for phosphoenolpyruvate limits the concentration and yield of natural products microbially synthesized via
K. M. Draths (2715604)   +2 more
core   +1 more source

Genomic Analysis of Microbulbifer sp. Strain A4B-17 and the Characterization of Its Metabolic Pathways for 4-Hydroxybenzoic Acid Synthesis

open access: yesFrontiers in Microbiology, 2018
The marine bacterium Microbulbifer sp. A4B-17 produces secondary metabolites such as 4-hydroxybenzoic acid (4HBA) and esters of 4HBA (parabens). 4HBA is a useful material in the synthesis of the liquid crystal.
Jun Tian   +8 more
doaj   +1 more source

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