Results 51 to 60 of about 15,124 (230)

Pathway-based screening strategy for multitarget inhibitors of diverse proteins in metabolic pathways. [PDF]

open access: yesPLoS Computational Biology, 2013
Many virtual screening methods have been developed for identifying single-target inhibitors based on the strategy of "one-disease, one-target, one-drug".
Kai-Cheng Hsu   +4 more
doaj   +1 more source

Combining phenotypic, physiological, and multi‐omics studies to provide new insights on the role of 2,4‐epibrassinolide in regulation of seed shattering in Elymus sibiricus L.

open access: yesGrassland Research, EarlyView.
Abstract Background Seed shattering limits the production of Elymus sibiricus L., and application of exogenous brassinosteroid significantly alleviates plant organ abscission. Methods To explore the potential regulatory network of brassinosteroid on seed shattering, the abscission zone of E. sibiricus cv. Lanyu No.
Huanhuan Lu   +6 more
wiley   +1 more source

Some studies on shikimate kinase. [PDF]

open access: yes, 1993
The mechanisms of the enzymes of the shikimate pathway, and the mechanisms of phosphoryl transfer by kinases in general are reviewed in chapter 1. In chapter 2, the preparation of B,y-[18O]ATP, alpha,beta-[18O]ADP, alpha,beta-[18O]ATP, and alpha1,beta ...
Mark Eric. Buttrum (7700045)
core  

Chromosome‐level genome and methylome of vine tea suggest roles for tandem duplication and CHH hypomethylation in high dihydromyricetin accumulation

open access: yesiMetaOmics, EarlyView.
A chromosome‐level genome assembly and single‐base resolution methylome of vine tea (Nekemias grossedentata) reveal that lineage‐specific tandem duplications of dihydromyricetin (DHM) biosynthetic genes (NgCHS and NgF3′5′ H) have expanded their copy numbers, providing the genetic basis for high DHM flux.
Yingmei Wu   +11 more
wiley   +1 more source

Comprehensive elucidation of volatile, phenolic, and organic acid profiles in Turkish mallow (Malva sylvestris L.) petal herbal tea: impact of diverse brewing conditions

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Mallow (Malva sylvestris L.) petals are traditionally consumed as herbal tea across the Mediterranean for their soothing and anti‐inflammatory properties; however, scientific characterization of this consumption‐relevant matrix under realistic brewing conditions remains scarce.
Armin Amanpour   +2 more
wiley   +1 more source

Sublethal herbicide exposure alters cotton susceptibility to aphid infestation

open access: yesPest Management Science, EarlyView.
Sublethal herbicide exposure altered cotton susceptibility to aphids. Aphid severity was highest when applications occurred at early vegetative stages and declined as the crop matured. In glasshouse, herbicide effects were dose‐dependent. Abstract BACKGROUND Herbicides remain vital tools for weed control, yet their effects can extend beyond weeds to ...
Purushottam Gyawali   +4 more
wiley   +1 more source

Metabolic Engineering of the Shikimate Pathway for Production of Aromatics and Derived Compounds—Present and Future Strain Construction Strategies

open access: yesFrontiers in Bioengineering and Biotechnology, 2018
The aromatic nature of shikimate pathway intermediates gives rise to a wealth of potential bio-replacements for commonly fossil fuel-derived aromatics, as well as naturally produced secondary metabolites.
Nils J. H. Averesch, Jens O. Krömer
doaj   +1 more source

EPSP Synthase-Depleted Cells Are Aromatic Amino Acid Auxotrophs in Mycobacterium smegmatis

open access: yesMicrobiology Spectrum, 2021
The epidemiological importance of mycobacterial species is indisputable, and the necessity to find new molecules that can inhibit their growth is urgent.
Mario Alejandro Duque-Villegas   +15 more
doaj   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

open access: yesPest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti   +3 more
wiley   +1 more source

The shikimate pathway and its branches in apicomplexan parasites [PDF]

open access: yes, 2002
The shikimate pathway is essential for production of a plethora of aromatic compounds in plants, bacteria, and fungi. Seven enzymes of the shikimate pathway catalyze sequential conversion of erythrose 4-phosphate and phosphoenol pyruvate to chorismate ...
Milhous, W K   +29 more
core   +1 more source

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