Results 71 to 80 of about 14,898 (199)

Molecular models for shikimate pathway enzymes of Xylella fastidiosa

, 2004
The Xylella fastidiosa is a bacterium that is the cause of citrus variegated chlorosis (CVC). The shikimate pathway is of pivotal importance for production of a plethora of aromatic compounds in plants, bacteria, and fungi.
Basso, L. A., Palma, Mario Sergio, da Silveira, NJF, Palma, Mario Sergio [UNESP], Arcuri, H. A., Pereira, J. H., de Oliveira, J. S., Camera, J. C., de Azevedo, W. F., Canduri, F., Santos, D. S.   +10 more
core   +1 more source

TARGETING 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE AND THE SHIKIMATE PATHWAY [PDF]

, 2008
Bacteria, plants, fungi, and apicomplexan parasites require the functionality of the shikimate pathway for biosynthesis of essential aromatic compounds. Animals lack the enzymes that constitute the shikimate pathway, making these attractive antimicrobial
Funke, Todd Arnold
core  

Metabolic engineering of Corynebacterium glutamicum for the production of anthranilate from glucose and xylose

Microbial Biotechnology
Anthranilate and its derivatives are important basic chemicals for the synthesis of polyurethanes as well as various dyes and food additives. Today, anthranilate is mainly chemically produced from petroleum‐derived xylene, but this shikimate pathway ...
Mario Mutz, Vincent Brüning, Christian Brüsseler, Moritz‐Fabian Müller, Stephan Noack, Jan Marienhagen   +5 more
doaj   +1 more source

Expression profiles of genes in the shikimate and benzenoid biosynthesis.

, 2018
Expression profiles of genes in the shikimate and benzenoid biosynthesis.
Xiuxian Ye (5720666), Huaiqin Zhong (5720669), Yiquan Chen (5720663), Ronghui Fan (5720660), Jianshe Wu (453816), Bing Lin (136655)   +5 more
core   +1 more source

Molecular Cloning of Plasmodium Shikimate Kinase

, 2017
Malaria is a disease that has a significant global burden and is both economically and clinically obstructive. New attempts to target the causative agent, the Plasmodium parasite, are focusing on the shikimate biosynthetic pathway due to both its role in
Noor, Ahmed
core  

Targeting upstream and downstream arms of the bacterial shikimate metabolic network as an opportunity for antibacterial and antivirulence therapy

Discover Bacteria
The shikimate pathway is an essential metabolic route in bacteria that generates chorismate, a central intermediate linking primary metabolism to the biosynthesis of aromatic amino acids and diverse infection-relevant metabolites.
Reuben S. Maghembe
doaj   +1 more source

Studies of the Shikimate Pathway Enzyme, 3-Dehydroquinase [PDF]

, 1993
1. Chemical modification with diethylpyrocarbonate (DEPC) and kinetic analyses have established a role for a single active site histidine residue as the general base involved in the mechanism of the type I dehydroquinase of E. coli. 2.
Deka, Ranjit Kumar
core  

Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase

The X-ray crystal structure of Mycobacterium tuberculosis shikimate kinase (SK) with bound shikimate and adenosine diphosphate (ADP) has been determined to a resolution of 2.15 Å.
Dhaliwal B, Nichols CE, Lockyer M, Charles I, Ren J, Stammers DK, Hawkins AR   +6 more
core  

Innovating a Nonconventional Yeast Platform for Producing Shikimate as the Building Block of High-Value Aromatics

, 2016
The shikimate pathway serves an essential role in many organisms. Not only are the three aromatic amino acids synthesized through this pathway, but many secondary metabolites also derive from it.
Adam Okerlund (3130596), Natalia Rodriguez Quiroz (3130587), Yutong Wu (3130584), Levi Stanley (3070905), Jacqueline V. Shanks (529246), Miguel Suástegui (3130593), James Walker (525818), Dana Tribby (3130581), Zengyi Shao (1883758), Meirong Gao (3130590), Mingfeng Cao (577797)   +10 more
core   +1 more source

Engineering of Corynebacterium glutamicum for the synthesis of aromatic compounds

Applied Microbiology and Biotechnology
A significant proportion of industrially important small molecules are aromatic, and the majority of these compounds are produced chemically, relying heavily on fossil resources.
Jan Marienhagen
doaj   +1 more source