Results 61 to 70 of about 15,124 (230)

SKPDB: a structural database of shikimate pathway enzymes

BMC Bioinformatics, 2010
Background The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design.
de Azevedo Walter F, Machado José M, da Silveira Nelson JF, Bonalumi Carlos E, Marucci Evandro A, Zafalon Geraldo FD, Arcuri Helen A, Palma Mário S   +7 more
doaj   +1 more source

Shikimate binding in Helicobacter pylori Shikimate Kinase

The FASEB Journal, 2006
Shikimate kinase (EC 2.7.1.71) catalyzes the specific phosphorylation of the 3‐hydroxyl group of shikimic acid in the presence of ATP. As the fifth key step in shikimate pathway for aromatic amino acid biosynthesis in bacteria, fungi, and plants, but not mammals, shikimate kinase represents an attractive target for the development ...
Wen‐Chi Cheng, Chiu‐Lien Hung, Yu‐Ning Chang, Wen‐Ching Wang   +3 more
openaire   +1 more source

A factorial multi‐layer analysis reveals non‐additive sulfur–iron interactions shaping metabolic and transcriptional responses in durum wheat

New Phytologist, EarlyView.
Working model of S‐dependent Fe stress integration in durum wheat. S availability acts as the main factor defining the metabolic and transcriptional state of the plant, whereas Fe mainly affects the intensity of these responses. This is particularly evident for OAS, methionine, citrate and asparagine, which accumulated most strongly under combined S ...
Eleonora Coppa, Mutsumi Watanabe, Moez Maghrebi, Giulia Quagliata, Alessandro Bruschini, Rainer Hoefgen, Youry Pii, Stefano Cesco, Gianpiero Vigani, Stefania Astolfi   +9 more
wiley   +1 more source

Computational modelling provides insight into the effects of glyphosate on the shikimate pathway in the human gut microbiome

Current Research in Toxicology, 2020
The herbicide active ingredient glyphosate can affect the growth of microorganisms, which rely on the shikimate pathway for aromatic amino acid biosynthesis.
Robin Mesnage, Michael N. Antoniou
doaj   +1 more source

Metabolomic Analysis Reveals Structural Diversity of Pectic Polysaccharides From Prunus persica (L.) Batsch and Their Relationship With Purees Characteristics

Plant Biotechnology Journal, EarlyView.
ABSTRACT To clarify how pectin heterogeneity relates to puree quality, this study investigated associations among pectin fractions, metabolite profiles, and physicochemical properties of peach purees from 20 cultivars with distinct viscosity, turbidity, and colour.
Meng Liu, Xuan Liu, Shaojie Fu, Qianhui Yang, Christophe Blecker, Jinfeng Bi   +5 more
wiley   +1 more source

Structural basis for shikimate-binding specificity of Helicobacter pylori shikimate kinase [PDF]

, 2010
[[abstract]]Shikimate kinase (EC 2.7.1.71) catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid in the presence of ATP. As the fifth key step in the shikimate pathway for aromatic amino acid biosynthesis in bacteria, fungi, and
Cheng WC;Chang YN;Wang WC
core  

Transcriptional changes in shikimate and phenylpropanoid biosynthesis pathways. [PDF]

, 2013
A: The expression patterns of genes in the shikimate and phenylpropanoid biosynthesis pathway. The scale bar displays log2-transformed fold changes. B: The metabolic view of shikimate and phenylpropanoid biosynthesis pathways.
Tong Wei (395347), Li-Jia Qu (395354), Jinbin Li (395349), Yang Zhao (39052), Youyong Zhu (369050), Dongshu Guo (395350), Genji Qin (395353), Hongya Gu (395352), Bin Ou (395348), Zhangliang Chen (395351), Chengyun Li (369037)   +10 more
core   +1 more source

Altered profile of floral volatiles and lignin content by down-regulation of Caffeoyl Shikimate Esterase in Petunia

BMC Plant Biology, 2023
Background The floral volatile profile of Petunia x hybrida ‘Mitchell diploid’ (MD) is dominated by phenylpropanoids, many of which are derived from p-coumaric acid.
Joo Young Kim, Keun Ho Cho, Shea A. Keene, Thomas A. Colquhoun   +3 more
doaj   +1 more source

Simultaneous Overexpression of FERULOYL‐CoA 6′‐HYDROXYLASE 1 and COUMARIN SYNTHASE Leads to Coumarin‐Enriched Lignin and Improved Saccharification in Greenhouse‐ and Field‐Grown Poplar

Plant Biotechnology Journal, EarlyView.
ABSTRACT The urgent need for renewable resources has increased the interest in woody biomass to manufacture bio‐based products. However, lignin recalcitrance limits the enzymatic conversion of wood into fermentable sugars, posing a major challenge for biomass deconstruction.
Nette De Ridder, Lennart Hoengenaert, Jan Van Doorsselaere, Wim De Clercq, Geert Goeminne, Sarah Liu, Fachuang Lu, John Ralph, Ruben Vanholme, Wout Boerjan   +9 more
wiley   +1 more source

Unexpected Suppression of Tomato Fruit Cuticle Formation by Overexpression of a Key Cutin Biosynthetic Enzyme

Plant Biotechnology Journal, EarlyView.
ABSTRACT Fruit cuticles regulate the diffusion of water, gases and solutes, functioning as essential protective interfaces against environmental and biotic stresses. Engineering cuticle structure and mechanics therefore represents a promising strategy for improving fruit quality and resilience.
Gulab Chand Arya, Ekram Wassel, Vibha Mishra, Ekaterina Manasherova, Ruth E. Stark, Hagai Cohen   +5 more
wiley   +1 more source