Results 11 to 20 of about 211,619 (263)
Short-chain fatty acids in diseases
AbstractShort-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such as monocarboxylate transporter 1 and sodium-coupled monocarboxylate transporter 1, which promote cellular metabolism. An increasing number
Dan Zhang +9 more
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Exogenous Short Chain Fatty Acid Effects in APP/PS1 Mice
Elucidating the impact of the gut microbiome on Alzheimer’s Disease (AD) is an area of intense interest. Short chain fatty acids (SCFAs) are major microbiota metabolites that have been implicated as a mediator of gut microbiome effects in the brain. Here,
Diana J. Zajac +5 more
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Objectives:. The intestinal microbiome can modulate immune function through production of microbial-derived short-chain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain fatty ...
Scott L. Weiss, MD, MSCE +14 more
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The relationship between diet and the diversity and function of the intestinal microbiomeand its importance for human health is currently the subject of many studies. The type and proportionof microorganisms found in the intestines can determine the energy balance of the host.
Paulina Markowiak-Kopeć +1 more
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Global obesity rates are increasing more and more. Short-chain fatty acids, the end products of fermentation of indigestible carbohydrates by intestinal bacteria, can influence metabolism and therefore play a role in the development of obesity and diabetes.
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Accumulating evidence implicates gut-microbiota-derived metabolites as important regulators of host energy balance and fuel homeostasis, the underlying mechanisms are currently subject to intense research.
Dehuang Kong +2 more
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Short-chain fatty acids in cancer pathogenesis
AbstractCancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious agents, mutations, diet, and environmental carcinogens. Homeostasis, which contributes importantly to the definition of “health,” is maintained, in part by the production of short-chain fatty acids ...
Mark A. Feitelson +3 more
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Effects of Plant Polysaccharides on Intestinal Flora and Metabolism in Patients Investigated Using in Vitro Fermentation Model [PDF]
This study aims to investigate the effects of five plant polysaccharides from Radix Astragalus, Rhizoma Atractylodis, Radix Scrophulariae, jujubes, Fructus mume on intestinal microorganisms and their metabolites in patients with type 2 diabetes mellitus (
JIA Lina, MA Qian, WANG Xinyue, GE Yanyan, WANG Nan, HE Hongpeng, LUO Xuegang, ZHU Liying, JIA Weiguo, HAO Lizhuang, QI Wei
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We investigated the ability of lactic acid bacteria, when added individually or in combination in feeds, to prevent soybean meal-induced enteritis in Atlantic salmon.
Nadanasabesan Nimalan +9 more
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Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites
This study was aimed to evaluate the differences in the composition of gut microbiota, tryptophan metabolites and short-chain fatty acids in feces between volunteers who frequently ate chicken and who frequently ate pork.
Jie Shi +5 more
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