Results 11 to 20 of about 211,619 (263)

Short-chain fatty acids in diseases

open access: yesCell Communication and Signaling, 2023
AbstractShort-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such as monocarboxylate transporter 1 and sodium-coupled monocarboxylate transporter 1, which promote cellular metabolism. An increasing number
Dan Zhang   +9 more
openaire   +3 more sources

Exogenous Short Chain Fatty Acid Effects in APP/PS1 Mice

open access: yesFrontiers in Neuroscience, 2022
Elucidating the impact of the gut microbiome on Alzheimer’s Disease (AD) is an area of intense interest. Short chain fatty acids (SCFAs) are major microbiota metabolites that have been implicated as a mediator of gut microbiome effects in the brain. Here,
Diana J. Zajac   +5 more
doaj   +1 more source

Decreased Intestinal Microbiome Diversity in Pediatric Sepsis: A Conceptual Framework for Intestinal Dysbiosis to Influence Immunometabolic Function

open access: yesCritical Care Explorations, 2021
Objectives:. The intestinal microbiome can modulate immune function through production of microbial-derived short-chain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain fatty ...
Scott L. Weiss, MD, MSCE   +14 more
doaj   +1 more source

Short-Chain Fatty Acids [PDF]

open access: yes, 2020
The relationship between diet and the diversity and function of the intestinal microbiomeand its importance for human health is currently the subject of many studies. The type and proportionof microorganisms found in the intestines can determine the energy balance of the host.
Paulina Markowiak-Kopeć   +1 more
openaire   +1 more source

Short-chain fatty acids [PDF]

open access: yes, 2021
Global obesity rates are increasing more and more. Short-chain fatty acids, the end products of fermentation of indigestible carbohydrates by intestinal bacteria, can influence metabolism and therefore play a role in the development of obesity and diabetes.
openaire   +2 more sources

Distinct Effects of Short Chain Fatty Acids on Host Energy Balance and Fuel Homeostasis With Focus on Route of Administration and Host Species

open access: yesFrontiers in Neuroscience, 2021
Accumulating evidence implicates gut-microbiota-derived metabolites as important regulators of host energy balance and fuel homeostasis, the underlying mechanisms are currently subject to intense research.
Dehuang Kong   +2 more
doaj   +1 more source

Short-chain fatty acids in cancer pathogenesis

open access: yesCancer and Metastasis Reviews, 2023
AbstractCancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious agents, mutations, diet, and environmental carcinogens. Homeostasis, which contributes importantly to the definition of “health,” is maintained, in part by the production of short-chain fatty acids ...
Mark A. Feitelson   +3 more
openaire   +2 more sources

Effects of Plant Polysaccharides on Intestinal Flora and Metabolism in Patients Investigated Using in Vitro Fermentation Model [PDF]

open access: yesShipin Kexue, 2023
This study aims to investigate the effects of five plant polysaccharides from Radix Astragalus, Rhizoma Atractylodis, Radix Scrophulariae, jujubes, Fructus mume on intestinal microorganisms and their metabolites in patients with type 2 diabetes mellitus (
JIA Lina, MA Qian, WANG Xinyue, GE Yanyan, WANG Nan, HE Hongpeng, LUO Xuegang, ZHU Liying, JIA Weiguo, HAO Lizhuang, QI Wei
doaj   +1 more source

Supplementation of lactic acid bacteria has positive effects on the mucosal health of Atlantic salmon (Salmo salar) fed soybean meal

open access: yesAquaculture Reports, 2023
We investigated the ability of lactic acid bacteria, when added individually or in combination in feeds, to prevent soybean meal-induced enteritis in Atlantic salmon.
Nadanasabesan Nimalan   +9 more
doaj   +1 more source

Chicken-eaters and pork-eaters have different gut microbiota and tryptophan metabolites

open access: yesScientific Reports, 2021
This study was aimed to evaluate the differences in the composition of gut microbiota, tryptophan metabolites and short-chain fatty acids in feces between volunteers who frequently ate chicken and who frequently ate pork.
Jie Shi   +5 more
doaj   +1 more source

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