Results 51 to 60 of about 65,690 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inovação Social e Tecnologia Social. O Caso da Cadeia Curta de Agricultores Familiares e a Alimentação Escolar em Porto Alegre/RS

Desenvolvimento em Questão, 2016
In the global scenario, social and environmental problems are challenges that mobilize the searchfor alternatives to the current paradigm, such as social innovation and social technology.
Gabriel Borela Franzoni, Tania Nunes da Silva   +1 more
doaj  

Smart cities through urban short supply chains of food.

, 2023
The cities around the world in general and in the Mediterranean area in particular are facing tremendous challenges at the environmental, social, economic and institutional levels (Fernandez-Anez et al., 2020). Currently, cities need to be sustainable and smart (Silva et al., 2018). An economically important and innovative sector in urban areas is food
Mata, F., Dos Santos, Maria José Palma Lampreia, Baptista, Nuno, Jesus Silva, Natacha   +3 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Food safety requirements in case of short food supply chain [PDF]

Studia Mundi – Economica, 2018
It can be stated according to the relevant literature that the health related characteristics of the food products and the ethical values relating to the sustainable development and consumption gains on a growing importance among the preferences of the consumers.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transforming food systems in Semarang City, Indonesia: A short food supply chain model

Open Agriculture
Industrialized agro-food supply systems often negatively impact health, social relationships, and the environment. Short food supply chains (SFSCs) have emerged as a sustainable alternative, improving farmers’ livelihoods and reconnecting producers with ...
Widianarko Budi, Hantoro Inneke, Putri Novita Ika, Nugrahedi Probo Yulianto   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Innovation in isolation: diffusion of local foods purchasing and online shopping methods during the pandemic

Frontiers in Sustainable Food Systems
IntroductionThe COVID-19 pandemic caused mainstream food supply chain disruptions, increased food security concerns, and impacted agri-food production and distribution systems.
Cheng-Xian Yang, Lauri M. Baker, Lauri M. Baker, Anissa M. Mattox, Hikaru H. Peterson   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source