Results 81 to 90 of about 6,019,441 (302)

Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]

, 2019
The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B, Li, Qiongyu, Wong, Maurice, Xie, Yixuan   +3 more
core   +2 more sources

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Structures of B-lymphotropic polyomavirus VP1 in complex with oligosaccharide ligands. [PDF]

PLoS Pathogens, 2013
B-Lymphotropic Polyomavirus (LPyV) serves as a paradigm of virus receptor binding and tropism, and is the closest relative of the recently discovered Human Polyomavirus 9 (HPyV9).
Ursula Neu, Zaigham Mahmood Khan, Benjamin Schuch, Angelina S Palma, Yan Liu, Michael Pawlita, Ten Feizi, Thilo Stehle   +7 more
doaj   +1 more source

Evaluation of salivary sialic acid and salivary Alpha-L-Fucosidase levels in patients with oral submucous fibrosis- A cross-sectional study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Saliva, a non-invasive diagnostic tool, is used to evaluate sialic acid and Alpha-L-Fucosidase in OSMF. Sialylation and fucosylation are glycosylation changes that mediate vital biological functions.
Sunaina Swatantramath, Daya K Jangam, Kajol Talreja, Pranali Bahadure, Antara Kore   +4 more
doaj   +1 more source

Biophysical analysis of sialic acid recognition by the complement regulator Factor H

Glycobiology, 2018
Complement factor H (FH), an elongated and substantially glycosylated 20-domain protein, is a soluble regulator of the complement alternative pathway (AP).
C. Schmidt, Agnes L. Hipgrave Ederveen, M. Harder, M. Wuhrer, T. Stehle, B. Blaum   +5 more
semanticscholar   +1 more source

The mucin-degradation strategy of Ruminococcus gnavus:The importance of intramolecular trans-sialidases [PDF]

, 2016
We previously identified and characterized an intramolecular trans-sialidase (IT-sialidase) in the gut symbiont Ruminococcus gnavus ATCC 29149, which is associated to the ability of the strain to grow on mucins. In this work we have obtained and analyzed
Crossman, Lisa C., Crost, Emmanuelle H, Henrissat, Bernard, Juge, Nathalie, Monestier, Marie, Swarbreck, David, Tailford, Louise E   +6 more
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Synthesis of bone meal-derived 4-carboxyphenylboronic acid functionalized sulfur and nitrogen co-doped graphene quantum dots nanoprobe for sialic acid sensing

Acta Chimica Slovenica
Detecting sialic acid using sensor-based technology in milk-based products is crucial. Therefore, present work reported the sulfur and nitrogen-doped graphene quantum dots from bone meal functionalized with boronic acid (Boro-S/N-dGQDs) nanoprobe for ...
Sopan Nangare, Pratik Yeole, Zamir Khan, Ashwini Patil, Bhushankumar Sathe, Sanjaykumar Bari, Pravin Onkar Patil   +6 more
doaj   +1 more source

Glycosidation of sialic acid.

Journal of Synthetic Organic Chemistry, Japan, 1989
N-Acetylneuraminic acid (Neu5Ac), a typical sialic acid, located at the non-reducing ends of carbohydrate chains of glycoproteins and glycolipids plays an important role in biological phenomena. The synthesis of oligosaccharides which contain Neu5Ac has focused with clarification of their vital functions.
Kaoru Okamoto, Toshio Goto
openaire   +2 more sources

The role of cellular adhesion molecules in virus attachment and entry [PDF]

, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source