Results 11 to 20 of about 70,452 (316)
Journal of Biological Chemistry, 1973 Abstract A soluble sialyltransferase was partially purified from colostrum (goat, bovine, and human). This enzyme catalyzed the transfer of sialic acid from cytidine monophospho-sialic acid to β-d-galactopyranosides. When N-acetyllactosamine was the acceptor, the products formed by the colostrum transferase contained sialic acid linked only to C-6 of ...
Bruce A. Bartholomew +2 more
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The Biosynthesis of Sialic Acids
Journal of Biological Chemistry, 1962 Herbert Felsenfeld, Leonard Warren
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Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:Leishmania donovani, belonging to a unicellular protozoan parasite, display the differential level of linkage-specific sialic acids on their surface.
Saptarshi Roy, Chitra Mandal
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Polymer-stabilized sialylated nanoparticles : synthesis, optimization, and differential binding to influenza hemagglutinins [PDF]
, 2020 During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell's surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids.
Baker, Alexander +3 more
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Lectin-conjugated pH-responsive mesoporous silica nanoparticles for targeted bone cancer treatment [PDF]
Acta Biomaterialia. 65, 393-404 (2018), 2021 A novel multifunctional nanodevice based in doxorubicin (DOX)- loaded mesoporous silica nanoparticles (MSNs) as nanoplatforms for the assembly of different building blocks has been developed for bone cancer treatment. These building blocks consists of: i) a polyacrylic acid (PAA) capping layer grafted to MSNs via an acid-cleavable acetal linker, to ...
arxiv +1 more source
Sialic acids in gastropods [PDF]
FEBS Letters, 2001 The occurrence of N‐acetylneuraminic acid and N‐glycolylneuraminic acid residues in preparations of the slug Arion lusitanicus (Gastropoda) was determined by sodium dodecyl sulphate electrophoresis of the proteins followed by lectin blots stained with the sialic acid specific lectin from Maackia amurensis, by the sensitivity of this binding to ...
Sabine Bürgmayr +2 more
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Determination of sialic acids in the nervous system of silkworm (Bombyx mori L.): Effects of aging and development [PDF]
Archives of Biological Sciences, 2017 Sialic acids mainly occur as components on cell surface glycoproteins and glycolipids. They play a major role in the chemical and biological diversity of glycoconjugates. Although sialic acids exhibit great structural variability in vertebrates,
Soya Seçkin +3 more
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Advances in Nutrition, 2012 Early postnatal development encounters milk as a key environmental variable and yet the sole nutrient source. One evolutionary conserved constituent of milk is sialic acid, which is generally displayed on glycoconjugates and free glycans. During early postnatal development, high sialic acid need was proposed to be unmet by the endogenous sialic acid ...
Norbert Sprenger, Peter I. Duncan
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Sialic Acids: An Important Family of Carbohydrates Overlooked in Environmental Biofilms
Applied Sciences, 2020 Sialic acids in the structural matrix of biofilms developing in engineered water systems constitute a potential target in the battle against biofouling.
Ingrid S.M. Pinel +5 more
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mBio, 2021 All cells in vertebrates are coated with a dense array of glycans often capped with sugars called sialic acids. Sialic acids have many functions, including serving as a signal for recognition of “self” cells by the immune system, thereby guiding an ...
Sudeshna Saha +15 more
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