Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm. [PDF]
PLoS Neglected Tropical Diseases, 2016 BACKGROUND:Leishmania donovani, belonging to a unicellular protozoan parasite, display the differential level of linkage-specific sialic acids on their surface.
Saptarshi Roy, Chitra Mandal
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Intramolecular Lactones of Sialic Acids. [PDF]
Int J Mol Sci, 2020 The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
Rota P +4 more
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Sialic acids in gastropods [PDF]
FEBS Letters, 2001 The occurrence of N‐acetylneuraminic acid and N‐glycolylneuraminic acid residues in preparations of the slug Arion lusitanicus (Gastropoda) was determined by sodium dodecyl sulphate electrophoresis of the proteins followed by lectin blots stained with the sialic acid specific lectin from Maackia amurensis, by the sensitivity of this binding to ...
Sabine Bürgmayr +2 more
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Polymer-stabilized sialylated nanoparticles : synthesis, optimization, and differential binding to influenza hemagglutinins [PDF]
, 2020 During influenza infection, hemagglutinins (HAs) on the viral surface bind to sialic acids on the host cell's surface. While all HAs bind sialic acids, human influenza targets terminal α2,6 sialic acids and avian influenza targets α2,3 sialic acids.
Baker, Alexander +3 more
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Determination of sialic acids in the nervous system of silkworm (Bombyx mori L.): Effects of aging and development [PDF]
Archives of Biological Sciences, 2017 Sialic acids mainly occur as components on cell surface glycoproteins and glycolipids. They play a major role in the chemical and biological diversity of glycoconjugates. Although sialic acids exhibit great structural variability in vertebrates,
Soya Seçkin +3 more
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Biological Functions and Analytical Strategies of Sialic Acids in Tumor
Cells, 2020 Sialic acids, a subset of nine carbon acidic sugars, often exist as the terminal sugars of glycans on either glycoproteins or glycolipids on the cell surface.
Xiaoman Zhou, Ganglong Yang, Feng Guan
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Advances in Nutrition, 2012 Early postnatal development encounters milk as a key environmental variable and yet the sole nutrient source. One evolutionary conserved constituent of milk is sialic acid, which is generally displayed on glycoconjugates and free glycans. During early postnatal development, high sialic acid need was proposed to be unmet by the endogenous sialic acid ...
Norbert Sprenger, Peter I. Duncan
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Synthesis of Sialic Acids and Sialic Acid Derivatives [PDF]
, 1982 Sialic acids as such, sialic acid derivatives, analogues, glycosides and sialooligosaccharides have been subject of many synthetic investigations. These studies were aimed at a further exploration of the properties of sialic acids, the preparation of substrates and inhibitors for sialidases, sialyltransferases or for sialic acid converting enzymes, and
Vliegenthart, J.F.G., Kamerling, J.P.
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Sialic Acids: An Important Family of Carbohydrates Overlooked in Environmental Biofilms
Applied Sciences, 2020 Sialic acids in the structural matrix of biofilms developing in engineered water systems constitute a potential target in the battle against biofouling.
Ingrid S.M. Pinel +5 more
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Sialic acids: An Avenue to Target Cancer Progression, Metastasis, and Resistance to Therapy
Forum of Clinical Oncology, 2022 Sialic acids are alpha-keto acids with nine carbons that are commonly present in the terminal sugars of glycans on glycoproteins and glycolipids on the cell surface.
Goni Mallikarjun +3 more
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