Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization [PDF]
Frontiers in Cell and Developmental Biology, 2022 Sialic acids are a family of 9-carbon monosaccharides with particular physicochemical properties. They modulate the biological functions of the molecules that carry them and are involved in several steps of the reproductive process.
Ingrid Fliniaux +8 more
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Sialoglycoproteins and N-Glycans from Secreted Exosomes of Ovarian Carcinoma Cells [PDF]
PLoS ONE, 2013 Exosomes consist of vesicles that are secreted by several human cells, including tumor cells and neurons, and they are found in several biological fluids.
Cristina Escrevente +2 more
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Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression [PDF]
Matrix Biology Plus, 2022 Tumors feature elevated sialoglycoprotein content. Sialoglycoproteins promote tumor progression and are linked to immune suppression via the sialic acid-Siglec axis.
Kevin James Metcalf +6 more
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Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis. [PDF]
Proc Natl Acad Sci U S A, 2021 © 2021 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/Blood pH is tightly maintained between 7.35 and 7.45, and acidosis (pH
Siddiqui SS +11 more
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NEU1 and NEU3 enzymes alter CD22 organization on B cells [PDF]
Biophysical Reports, 2022 The B cell membrane expresses sialic-acid-binding immunoglobulin-like lectins, also called Siglecs, that are important for modulating immune response. Siglecs have interactions with sialoglycoproteins found on the same membrane (cis-ligands) that result ...
Hanh-Thuc Ton Tran +3 more
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Identification of Novel Tumor-Associated Cell Surface Sialoglycoproteins in Human Glioblastoma Tumors Using Quantitative Proteomics [PDF]
PLoS ONE, 2014 Glioblastoma multiform (GBM) remains clinical indication with significant "unmet medical need". Innovative new therapy to eliminate residual tumor cells and prevent tumor recurrences is critically needed for this deadly disease.
Romane Auvergne +2 more
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Sugar Coating: Utilisation of Host Serum Sialoglycoproteins by Schistosoma mansoni as a Potential Immune Evasion Mechanism [PDF]
Pathogens, 2022 Parasitic helminths resort to various mechanisms to evade and modulate their host’s immune response, several of which have been described for Schistosoma mansoni.
Maude Dagenais +3 more
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Screening and Characterization of Sialic Acid-Binding Variable Lymphocyte Receptors from Hagfish [PDF]
BioTechSialic acid is a diverse group of monosaccharides often found on the termini of N- and O-linked glycans as well as being components of glycoconjugates.
Mark Rickard N. Angelia +9 more
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Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products. [PDF]
PLoS ONE, 2009 BackgroundHumans are genetically defective in synthesizing the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc), but can metabolically incorporate it from dietary sources (particularly red meat and milk) into glycoproteins and glycolipids ...
Sandra L Diaz +8 more
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Sialoglycoproteins from the Eggs of Pacific Herring [PDF]
European Journal of Biochemistry, 1980 A family of hitherto undescribed sialoglycoproteins has been isolated from the eggs of Pacific herring in a yield about 10 times as much as phosvitin known as a major protein component of the eggs. The sialoglycoproteins are composed of 60–50% of carbohydrate and 40–50% of protein.
Sadako Inoue, Mariko Iwasaki
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