Results 21 to 30 of about 4,387 (243)

Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis. [PDF]

PLoS ONE, 2011
Using a lectin, Achatinin-H, having preferential specificity for glycoproteins with terminal 9-O-acetyl sialic acid derivatives linked in α2-6 linkages to subterminal N-acetylgalactosamine, eight distinct disease-associated 9-O-acetylated ...
Sajal Samanta, Devawati Dutta, Angana Ghoshal, Sumi Mukhopadhyay, Bibhuti Saha, Shyam Sundar, Saulius Jarmalavicius, Michael Forgber, Chhabinath Mandal, Peter Walden, Chitra Mandal   +10 more
doaj   +1 more source

Roles of bovine sialoglycoproteins for anti‐skin aging and accelerating skin wound healing

Journal of Cosmetic Dermatology, Volume 22, Issue 12, Page 3470-3479, December 2023., 2023
Abstract Background Fibroblasts are the most predominant cell subpopulation in the dermal layer of human skin, they play an important role in maintaining skin architecture and function. The senescence of fibroblasts is one of major causes of skin aging and chronic wound in the elderly, which is accompanied with a reduction of α2,6‐sialylation on the ...
Xilong Wang, Lixin Yue, Fan Zhang, Xiaojuan Bao, Wanghua Song, Zheng Li   +5 more
wiley   +1 more source

TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5

Advanced Science, Volume 10, Issue 25, September 5, 2023., 2023
Tumor protein 53 regulating kinase (TP53RK) is positively correlated to renal dysfunction and fibrosis in chronic kidney disease (CKD). Deleting TP53RK in renal tubule or fibroblasts mitigates renal fibrosis. Mechanically, TP53RK phosphorylates baculoviral IAP repeat containing 5(Birc5) to promote partial epithelial‐mesenchymal transition in renal ...
Mengqiu Wu, Qianqian Jin, Xinyue Xu, Jiaojiao Fan, Weiyi Chen, Mengqiu Miao, Ran Gu, Shengnan Zhang, Yan Guo, Songming Huang, Yue Zhang, Aihua Zhang, Zhanjun Jia   +12 more
wiley   +1 more source

Gangliosides in milk

Mljekarstvo, 2016
Gangliosides belong to a group of glycosphingolipids which are naturally found in biological tissues and fluids including mammalian milks. Considering milk, gangliosides are exclusively found in the membrane of the milk fat globule.
Slavica Potočki, Marko Mesarić
doaj   +1 more source

Rapid chemical de-N-glycosylation and derivatization for liquid chromatography of immunoglobulin N-linked glycans. [PDF]

PLoS ONE, 2018
Glycan analysis may result in exploitation of glycan biomarkers and evaluation of heterogeneity of glycosylation of biopharmaceuticals. For N-linked glycan analysis, we investigated alkaline hydrolysis of the asparagine glycosyl carboxamide of ...
Akihiko Kameyama, Santha Kumara Dissanayake, Wai Wai Thet Tin   +2 more
doaj   +1 more source

Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization

JOR SPINE, Volume 6, Issue 3, September 2023., 2023
To date, there is a lack of consensus for the extraction, numeration, in vitro culture, and characterization of intervertebral disc notochordal cells (NCs). With large variations in methodological approaches affecting progress in this field. Thus, this article aims to provide key recommendations and methodologies for NC isolation, numeration, in vitro ...
Rebecca J. Williams, Lisanne T. Laagland, Frances C. Bach, Lizzy Ward, Wilson Chan, Vivian Tam, Adel Medzikovic, Shaghayegh Basatvat, Lily Paillat, Nicolas Vedrenne, Joseph W. Snuggs, Deepani W. Poramba‐Liyanage, Judith A. Hoyland, Danny Chan, Anne Camus, Stephen M. Richardson, Marianna A. Tryfonidou, Christine L. Le Maitre   +17 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

Mass Spectrometry Reviews, Volume 42, Issue 5, Page 1984-2206, September/October 2023., 2023
Abstract This review is the tenth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2020.
David J. Harvey
wiley   +1 more source

Gel filtration of sialoglycoproteins [PDF]

Biochemical Journal, 1978
The role of sialic acid in the gel-filtration behaviour of sialoglycoproteins was investigated by using the separated isoenzymes of purified human liver alpha-L-fucosidase and several other well-known sialic acid-containing glycoproteins (fetuin, alpha1-acid glycoprotein, thyroglobulin and bovine submaxillary mucin).
openaire   +3 more sources

Mechanism of Acyl Group Migration in Carbohydrates

Chemistry – A European Journal, Volume 29, Issue 43, August 1, 2023., 2023
Acyl groups are prone to migrate in carbohydrates, causing issues in the laboratory setting. Migration could also have biological relevance, such as in regulation of cell signaling. Recently, deeper investigations have been performed on the mechanism of this phenomenon.
Robert Lassfolk, Reko Leino
wiley   +1 more source

Inhibitory effects of Trypanosoma cruzi sialoglycoproteins on CD4+ T cells are associated with increased susceptibility to infection. [PDF]

PLoS ONE, 2013
BackgroundThe Trypanosoma cruzi infection is associated with severe T cell unresponsiveness to antigens and mitogens characterized by decreased IL-2 synthesis. Trypanosoma cruzi mucin (Tc Muc) has been implicated in this phenomenom.
Marise Pinheiro Nunes, Bárbara Fortes, João Luiz Silva-Filho, Eugênia Terra-Granado, Leonardo Santos, Luciana Conde, Isadora de Araújo Oliveira, Leonardo Freire-de-Lima, Marina Vieira Martins, Ana Acacia Sá Pinheiro, Christina Maeda Takyia, Célio Geraldo Freire-de-Lima, Adriane Regina Todeschini, George Alexandre Dosreis, Alexandre Morrot   +14 more
doaj   +1 more source