Results 71 to 80 of about 4,489 (227)

Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling

open access: yesClinical &Translational Immunology, Volume 13, Issue 9, September 2024.
In this study, we found high Siglec‐7 and Siglec‐9 (ligand) expression in triple negative breast cancer, and to a lower extent in oestrogen receptor positive breast cancer. Moreover, signalling experiments demonstrated that Siglec‐7 signalling is induced by triple negative breast cancer cell lines.
Eline JH van Houtum   +9 more
wiley   +1 more source

Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis [PDF]

open access: yes, 2013
Neuroblastoma, the most common extracranial pediatric solid tumor, is responsible for 15% of all childhood cancer deaths. Patients frequently present at diagnosis with metastatic disease, particularly to the bone marrow (BM).
Calabrese, Christopher   +13 more
core   +2 more sources

Identification and partial purification of K88ab Escherichia coli receptor proteins in porcine brush border membranes [PDF]

open access: yes, 2010
Six receptor proteins, with molecular masses ranging from 94 to 27 kDa, that bind to Escherichia coli K88ab fimbriae were recovered from brush border membranes and were detected after solubilization with Triton X-114.
J. Soler, M. Caloca, S. Suárez
core   +1 more source

Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. [PDF]

open access: yes, 2019
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Chen, Xi   +2 more
core   +2 more sources

CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

open access: yesJournal of Neuroscience Research, Volume 102, Issue 7, July 2024.
Proteoglycans are important multifunctional components of the central and peripheral nervous systems and represent a diverse group of specialized proteins that stabilize and functionalize these tissues. Abstract Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse functional roles, this study examined how these control ...
James Melrose
wiley   +1 more source

OMIP‐102: 50‐color phenotyping of the human immune system with in‐depth assessment of T cells and dendritic cells

open access: yesCytometry Part A, Volume 105, Issue 6, Page 430-436, June 2024.
Abstract We report the development of an optimized 50‐color spectral flow cytometry panel designed for the in‐depth analysis of the immune system in human blood and tissues, with the goal of maximizing the amount of information that can be collected using currently available flow cytometry platforms.
Andrew J. Konecny   +4 more
wiley   +1 more source

A case of extravascular hemolysis with Tk‐activation [PDF]

open access: yes, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108281/1/ccr380 ...
Davenport, Robertson D., Yamada, Chisa
core   +1 more source

Hyaluronan and chondroitin sulfate in chicken–vegetable bone broth delay osteoporosis progression

open access: yesJournal of Food Science, Volume 89, Issue 3, Page 1791-1803, March 2024.
Abstract Bone broth has recently gained worldwide recognition as a superfood that supplements several nutrients lacking in modern human diets; however, little is known of its efficacy on osteoporosis. Therefore, we aimed to identify the components of chicken–vegetable bone broth (CVBB) that are associated with osteoporosis prevention and verified the ...
Yuka Seki   +5 more
wiley   +1 more source

5. Vaccine development: basic considerations. Asexual blood stage vaccines: from merozoites to peptides [PDF]

open access: yes, 2017
Asexual blood stage proliferation is responsible for the morbidity and mortality associated with malaria infection in man. These developmental stages are therefore obvious targets for the development of malaria vaccines.
Fasani-Ghersa, P.   +2 more
core  

Apoptotic vesicles derived from human red blood cells promote bone regeneration via carbonic anhydrase 1

open access: yesCell Proliferation, Volume 57, Issue 2, February 2024.
Apoptotic vesicles derived from human red blood cells promoted the osteogenesis of human mesenchymal stem cells and enhanced bone regeneration via carbonic anhydrase I. The figure was created with BioRender.com. Abstract Apoptotic vesicles (apoVs) are nanoscale vesicles derived from billions of apoptotic cells involved in the maintenance of the human ...
Yuzi Shao   +8 more
wiley   +1 more source

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