Results 171 to 180 of about 11,605 (209)
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Structural insight into mammalian sialyltransferases
Nature Structural & Molecular Biology, 2009Mammalian cell surfaces are modified by complex arrays of glycoproteins, glycolipids and polysaccharides, many of which terminate in sialic acid and have central roles in essential processes including cell recognition, adhesion and immunogenicity.
Rao, Francesco V. +10 more
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A review on the development of sialyltransferase inhibitors
Carbohydrate ResearchSialylation of terminal glycoconjugates is involved in many important physiological and pathological processes such as tumor metastasis, drug resistance, organismal immunity, and viral infections. Sialyltransferases are enzymes responsible for sialylation modification in organisms, and potent sialyltransferase inhibitors can not only serve as probes ...
Xiang, Zhang, Xin-Shan, Ye
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Specificity of submaxillary gland sialyltransferases
Biochimica et Biophysica Acta (BBA) - General Subjects, 1983A method has been developed to determine the activities of specific sialyltransferases by analysis of the products of the reaction. This method, which utilizes high performance liquid chromatography, distinguishes addition of sialic acid to the N-acetylgalactosamine vs.
A P, Sherblom, C R, Bourassa
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Glycoprotein sialyltransferases in eucaryotic cells
International Journal of Biochemistry, 1991xxx
Broquet, P. +3 more
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Sperm-associated sialyltransferase activity
Nature, 1977FERTILISATION begins with a specific adhesion between sperm and egg and culminates with the fusion of the male and female pronuclei. In mammals, sperm seem to recognise the zona pellucida surrounding the egg1. This adhesive interaction is the first of many that will take place during subsequent embryogenesis.
R, Durr, B, Shur, S, Roth
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Journal of Biochemistry, 2007
A novel bacterium, Photobacterium sp. JT-ISH-224, that produces alpha-/beta-galactoside alpha2,3-sialyltransferase and beta-galactoside alpha2,6-sialyltransferase, was isolated from the gut of a Japanese barracuda. The genes that encode the enzymes were cloned from the genomic library of the bacterium using the genes encoding alpha-/beta-galactoside ...
H. Tsukamoto +3 more
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A novel bacterium, Photobacterium sp. JT-ISH-224, that produces alpha-/beta-galactoside alpha2,3-sialyltransferase and beta-galactoside alpha2,6-sialyltransferase, was isolated from the gut of a Japanese barracuda. The genes that encode the enzymes were cloned from the genomic library of the bacterium using the genes encoding alpha-/beta-galactoside ...
H. Tsukamoto +3 more
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Sialyltransferases of developing rat brain
Glycoconjugate Journal, 1990The activity of four different sialyltransferases acting on N- or O-linked chains of glycoproteins was studied in brains of 19 days-old embryos, 1-day-old newborns and adult rats. By using asialofetuin, fetuin and N-acetyllactosamine as acceptors, it has been possible to measure independently the following enzyme activities: CMP-NeuAc:Gal beta 1 ...
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Sialyltransferases in Young Rat Brain
19801. There are more glycolipid acceptor sites for NeuNAc than for glycoproteins in 11--15 day old rat cerebra. 2. The glycolipid acceptors appear to be almost exclusively Cer-Glc-Gal and GM1 ganglioside and each is a substrate for a different sialyltransferase. 3.
J A, Dain, S S, Ng
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1994, the year of sialyltransferases
Glycobiology, 1995Harduin-Lepers, Anne +2 more
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How stress affects sialyltransferase?
2002This abstract summerize how stress affect ...
Flogel-Mršić, Mirna +3 more
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