Results 91 to 100 of about 46,454 (250)
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy
Haematologica, 2015 Intravascular hemolysis and hemoglobinuria are associated with sickle cell nephropathy. ApoL1 is involved in cell-free hemoglobin scavenging through association with haptoglobin-related protein.
Santosh L. Saraf +10 more
doaj +1 more source
Sickle cell disease affects more than 100,000 individuals in the United States, among whom disease severity varies considerably. One factor that influences disease severity is the sickle cell disease genotype.
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Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]
, 2017 Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan +6 more
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva +7 more
wiley +1 more source
Nitrite decreases sickle hemoglobin polymerization in vitro independently of methemoglobin formation. [PDF]
Toxicol Appl Pharmacol, 2023 Almeida LEF +5 more
europepmc +1 more source
Journal of Diabetes Investigation, EarlyView.Under physiological conditions, deformable erythrocytes pass smoothly through the capillary network, maintaining retinal capillary perfusion (A). In pathological conditions, reduced erythrocyte deformability causes irregular passage and stagnation within capillaries, resulting in localized blood flow stasis and microvascular congestion, leading to ...
Ye Eun Han +5 more
wiley +1 more source
Nefrología (English Edition)Sickle cell disease, is a genetic disorder caused by a mutation in the HBB gene, affecting the β-globin and resulting in the formation of sickle hemoglobin.
Lina M. Garzón +3 more
doaj +3 more sources
Voxelotor does not inhibit sickle hemoglobin fiber formation upon complete deoxygenation. [PDF]
Biophys J, 2023 Worth EH, Fugate MK, Ferrone FA.
europepmc +1 more source
Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate
Journal of Microscopy, EarlyView.Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley +1 more source
An “acquired” hemoglobin J variant in a sickle cell disease patient
Therapeutics and Clinical Risk Management, 2008 Nawwar Swedan1, Kathleen Nicol2, Phylis Moder2, Samir Kahwash21Fellow in Transfusion Medicine, Ohio State University, Columbus, Ohio; 2Department of Laboratory Medicine, Nationwide Children’s Hospital, Columbus, OhioAbstract: We report the case
Nawwar Swedan +3 more
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