Results 91 to 100 of about 517,159 (303)

Interplay of Catalyst Structure and Temperature for NMR Signal Amplification by Reversible Exchange

, 2019
SABRE has brought up the many possibilities for chemical and medical researches. However, the current SABRE catalyst has multi-limitations, including the time-consuming activation, activation stability and temperature compatibility.
Fan, Shi, Fan Shi (6431153)
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Amplification sensing manipulated by a sumanene-based supramolecular polymer as a dynamic allosteric effector

Scientific Reports
The synthesis of signal-amplifying chemosensors induced by various triggers is a major challenge for multidisciplinary sciences. In this study, a signal-amplification system that was flexibly manipulated by a dynamic allosteric effector (trigger) was ...
Hiroaki Mizuno, Hironobu Nakazawa, Akihisa Miyagawa, Yumi Yakiyama, Hidehiro Sakurai, Gaku Fukuhara   +5 more
doaj   +1 more source

Research on Weak Signal Amplification Principle Based on Parabola Map

, 2010
In this paper, a new nonlinear amplification principle based on chaotic theory is proposed. Firstly, according to the basic properties of chaotic systems, such as the sensitivity of the initial conditions and the one-to-one correspondence between chaotic
Zhen Qiang Huang, Zhi Gang Wang, Wen Li Zhao   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Molecules
Enzyme-linked electrochemical immunosensors have attracted considerable attention for the sensitive and selective detection of various targets in clinical diagnosis, food quality control, and environmental analysis.
Ning Xia, Fengli Gao, Jiwen Zhang, Jiaqiang Wang, Yaliang Huang   +4 more
doaj   +1 more source

Amplification of electromagnetic signals by ion channels

Biophysical Journal, 1997
Cells may respond to the exposure of low-frequency electromagnetic fields with changes in cell division, ion influx, chemical reaction rates, etc. The chain of events leading to such responses is difficult to study, mainly because of extremely small energies associated with low-frequency fields, usually much smaller than the thermal noise level ...
Galvanovskis, J., Sandblom, J.
openaire   +2 more sources

Parametric Amplification of a 640 Gbit/s RZ-DPSK Signal [PDF]

, 2013
We report the first demonstration and characterization of parametric amplification of a 640Gbit/s RZ-DPSK OTDM signal. With proper design of the fiber parametric amplifier, error-free amplification with less than 1 dB penalty has been ...
Leif Katsuo Oxenløwe, Mulvad, Hans Christian Hansen, Galili, Michael, Hans Christian Hansen Mulvad, Lali-Dastjerdi, Zohreh, Peucheret, Christophe, Hao Hu, Hu, Hao, Michael Galili, Oxenløwe, Leif Katsuo, Christophe Peucheret, Rottwitt, Karsten, Zohreh Lali-Dastjerdi, Karsten Rottwitt   +13 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source