Results 101 to 110 of about 6,973,238 (322)

Nature and Characteristics of a Voltage-Biased Varistor and its Embedded Transistor

IEEE Journal of the Electron Devices Society, 2015
An unorthodox approach for producing simple and yet practical transistors based on ceramic platforms is discussed in this paper. To achieve this, we modify the original nonlinear current-voltage (I-V) characteristics of a varistor by superimposing a ...
Raghvendra K. Pandey, William A. Stapleton, Ivan Sutanto   +2 more
doaj   +1 more source

Signal Amplification in Living Cells: A Review of microRNA Detection and Imaging.

Analytical Chemistry, 2019
MicroRNAs (miRNAs) are a class of endogenous, non-coding RNAs with a typical length of 19-23 nucleotides. miRNAs regulate the expression of specific genes by binding to complementary regions of messenger RNA (mRNA), which represses mRNA translation or ...
Hanyong Peng, Ashley M Newbigging, Michael S. Reid, J. S. Uppal, Jingyang Xu, Hongquan Zhang, X. Le   +6 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Design of amplifying information metasurface for enhancing signal coverage

Tongxin xuebao, 2022
Traditional information metasurfaces can be used in wireless relay systems to control the propagation direction of electromagnetic waves due to their capability to control the amplitude and phase.However, owing to the lack of signal amplification ...
Lijie WU, Hanqing YANG, Qiang CHENG, Tiejun CUI   +3 more
doaj   +2 more sources

Design and Applications of Ratiometric Electrochemical Biosensors

International Journal of Electrochemical Science, 2019
Electrochemical biosensors have been used in the fields of disease diagnosis, environmental monitoring, and food safety. However, the traditional electrochemical biosensors have some shortcomings, such as poor stability and reproducibility.
Linlin Hou, Chunyan Duan, Panpan Ding
doaj   +1 more source

Nonreciprocal wave propagation and parametric amplification of bulk elastic waves in nonlinear anisotropic materials

New Journal of Physics, 2020
Parametric amplification of an elastic wave and a framework for using elastic waves that could enable a new generation of high performance, low noise acoustic amplifiers, mixers and circulators are presented.
Mahsa Zakeri, Scott M Keller, Yuanxun Ethan Wang, Christopher S Lynch   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Amplification sensing manipulated by a sumanene-based supramolecular polymer as a dynamic allosteric effector

Scientific Reports
The synthesis of signal-amplifying chemosensors induced by various triggers is a major challenge for multidisciplinary sciences. In this study, a signal-amplification system that was flexibly manipulated by a dynamic allosteric effector (trigger) was ...
Hiroaki Mizuno, Hironobu Nakazawa, Akihisa Miyagawa, Yumi Yakiyama, Hidehiro Sakurai, Gaku Fukuhara   +5 more
doaj   +1 more source

Noiseless Linear Amplification and Distillation of Entanglement

, 2009
The idea of signal amplification is ubiquitous in the control of physical systems, and the ultimate performance limit of amplifiers is set by quantum physics.
A Furusawa, A. P. Lund, AP Lund, B Hage, BL Higgins, CH Bennett, Ch Silberhorn, CM Caves, CW Chou, DE Browne, DT Pegg, F Grosshans, G. J. Pryde, G. Y. Xiang, H Takahashi, H-A Bachor, JP Dowling, K Mølmer, L-M Duan, N. Walk, R Dong, SA Babichev, SL Braunstein, T. C. Ralph, TC Ralph, TC Ralph, UL Andersen, WK Wootters, ZY Ou   +28 more
core   +1 more source