Results 41 to 50 of about 258,387 (282)
Interactions of signal peptides with signal-recognition particle [PDF]
Biochemical Journal, 1990 The mechanisms whereby isolated or synthetic signal peptides inhibit processing of newly synthesized prolactin in microsome-supplemented lysates from reticulocytes and wheat-germ were investigated. At a concentration of 5 microM, a consensus signal peptide reverses the elongation arrest imposed by the signal-recognition particle (SRP), and at higher ...
A, Robinson, O M, Westwood, B M, Austen
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Signal Recognition Particle (SRP) and SRP Receptor: A New Paradigm for Multistate Regulatory GTPases [PDF]
, 2009 The GTP-binding proteins or GTPases comprise a superfamily of proteins that provide molecular switches in numerous cellular processes. The “GTPase switch” paradigm, in which a GTPase acts as a bimodal switch that is turned “on” and “off” by external ...
Schmid, Sandra L. +2 more
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Frontiers in Molecular Biosciences, 2021 The spatial and temporal coordination of protein transport is an essential cornerstone of the bacterial adaptation to different environmental conditions.
Julia Oswald +7 more
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The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape [PDF]
, 2010 Phagocytosis is the fundamental cellular process by which eukaryotic cells bind and engulf particles by their cell membrane. Particle engulfment involves particle recognition by cell-surface receptors, signaling and remodeling of the actin cytoskeleton ...
Dart, Anna E. +3 more
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Direct visualization reveals dynamics of a transient intermediate during protein assembly [PDF]
, 2011 Interactions between proteins underlie numerous biological functions. Theoretical work suggests that protein interactions initiate with formation of transient intermediates that subsequently relax to specific, stable complexes.
Alberts +35 more
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Antibody to signal recognition particle in polymyositis [PDF]
Arthritis & Rheumatism, 1990 AbstractUsing immunoprecipitation, we identified 13 patients with antibodies to the signal recognition particle (SRP) from a collection of sera representing 265 poly‐myositis/dermatomyositis (PM/DM) patients. Antibody reactivity with SRP was confirmed by enzyme‐linked immunosorbent assay and immunoprecipitation with isolated dog pancreas SRP.
I N, Targoff, A E, Johnson, F W, Miller
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Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon
Nature Communications, 2016 The co-translational insertion of proteins into membranes requires interaction between a ribosome-bound signal recognition particle (SRP) and a membrane-bound translocon.
Ahmad Jomaa +3 more
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The Identification of ECG Signals Using WT-UKF and IPSO-SVM
Sensors, 2022 The biometric identification method is a current research hotspot in the pattern recognition field. Due to the advantages of electrocardiogram (ECG) signals, which are difficult to replicate and easy to obtain, ECG-based identity identification has ...
Ning Li +6 more
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Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting [PDF]
, 2010 Kinetic control of macromolecular interactions plays key roles in biological regulation. An example of such control occurs in cotranslational protein targeting by the signal recognition particle (SRP), during which the SRP RNA and the cargo both ...
Shan, Shu-ou, Shen, Kuang
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Signal recognition particle components in the nucleolus [PDF]
Proceedings of the National Academy of Sciences, 2000 The signal recognition particle (SRP) is a ribonucleoprotein composed of an Alu domain and an S domain. The S domain contains unique sequence SRP RNA and four SRP proteins: SRP19, SRP54, SRP68, and SRP72. SRP interacts with ribosomes to bring translating membrane and secreted proteins to the endoplasmic ...
Politz, Joan C. Ritland +5 more
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