Results 31 to 40 of about 81,913 (204)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Signal Recognition Particle Myopathy With Cardiac Manifestations in Rheumatoid Arthritis
Annals of Internal Medicine: Clinical CasesImmune-mediated necrotizing myopathy is a rare inflammatory myopathy characterized by progressive muscle weakness and potentially severe systemic complications.
Priya Sunkara +3 more
doaj +1 more source
IEEE Access, 2019 In order to realize the recognition of coal gangue in the top coal caving process, a scheme of the coal gangue recognition based on the collision vibration signal between coal gangue and the metal plate is proposed in this paper, a systematic and ...
Yang Yang +3 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
AtmosphereAccurate identification and monitoring of aerosol properties is crucial for understanding their sources and impacts on human health and the environment.
Heng Zhao +5 more
doaj +1 more source
Nature Communications, 2017 Membrane proteins are inserted co-transnationally through the association between ribosome, the signal recognition particle and its receptor, and the membrane-bound translocon.
Ahmad Jomaa +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Multi-feature radar signal modulation recognition based on improved PSO algorithm
The Journal of Engineering, 2019 In order to solve the problem that radar emitter signal modulation recognition under low signal-to-noise ratio (SNR) has difficulty in selecting the parameters of the classifier and the problem of low recognition rate caused by the improper selection of ...
Jing-Peng Gao +4 more
doaj +1 more source