Recognition of a signal peptide by the signal recognition particle [PDF]
Nature, 2010 Targeting of proteins to appropriate subcellular compartments is a crucial process in all living cells. Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome.
Janda, C +5 more
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Signal Recognition Particle: An Essential Protein-Targeting Machine [PDF]
Annual Review of Biochemistry, 2013 The signal recognition particle (SRP) and its receptor compose a universally conserved and essential cellular machinery that couples the synthesis of nascent proteins to their proper membrane localization. The past decade has witnessed an explosion in
Akopian, David +3 more
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A signal recognition particle-related joint model of LASSO regression, SVM-RFE and artificial neural network for the diagnosis of systemic sclerosis-associated pulmonary hypertension [PDF]
Frontiers in Genetics, 2022 Background: Systemic sclerosis-associated pulmonary hypertension (SSc-PH) is one of the most common causes of death in patients with systemic sclerosis (SSc).
Jingxi Xu +3 more
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Factors associated with refractory autoimmune necrotizing myopathy with anti-signal recognition particle antibodies [PDF]
Orphanet Journal of Rare Diseases, 2020 Background Autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (ANM-SRP) is regarded as refractory myositis, whereby some patients respond poorly to conventional immunosuppression and require B cell depletion treatment.
Yawen Zhao +4 more
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Signal Recognition Particle RNA Contributes to Oxidative Stress Response in Deinococcus radiodurans by Modulating Catalase Localization [PDF]
Frontiers in Microbiology, 2020 The proper functioning of many proteins requires their transport to the correct cellular compartment or their secretion. Signal recognition particle (SRP) is a major protein transport pathway responsible for the co-translational movement of integral ...
Runhua Han +10 more
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Molecular Mimicry of SecA and Signal Recognition Particle Binding to the Bacterial Ribosome [PDF]
mBio, 2019 Bacteria execute a variety of protein transport systems for maintaining the proper composition of their different cellular compartments. The SecYEG translocon serves as primary transport channel and is engaged in transporting two different substrate ...
Lara Knüpffer +5 more
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Structure and function of signal recognition particle (SRP) [PDF]
Molecular Biology Reports, 1993 Dobberstein, Berhard, Lütcke, Henrich
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Defence Technology, 2023 In order to improve the recognition rate and accuracy rate of projectiles in six sky-screens intersection test system, this work proposes a new recognition method of projectiles by combining particle swarm optimization support vector and spatial-temporal
Han-shan Li
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SRPDB (Signal Recognition Particle Database) [PDF]
Nucleic Acids Research, 2001 Signal recognition particle (SRP) is a stable cytoplasmic ribonucleoprotein complex that serves to translocate secretory proteins across membranes during translation. The SRP Database (SRPDB) provides compilations of SRP components, ordered alphabetically and phylogenetically.
J, Gorodkin +3 more
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SRPDB: Signal Recognition Particle Database [PDF]
Nucleic Acids Research, 2003 The Signal Recognition Particle Database (SRPDB) at http://psyche.uthct.edu/dbs/SRPDB/SRPDB.html and http://bio.lundberg.gu.se/dbs/SRPDB/SRPDB.html assists in the better understanding of the structure and function of the signal recognition particle (SRP), a ribonucleoprotein complex that recognizes signal sequences as they emerge from the ribosome ...
Rosenblad, Magnus Alm +4 more
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