Results 11 to 20 of about 82,494 (244)

Clinical Characteristics of Patients With Anti‐Signal Recognition Particle Antibody: A Cohort Study [PDF]

Immunity, Inflammation and Disease
Background Anti‐signal recognition particle (anti‐SRP) antibodies are myositis‐specific autoantibodies associated with immune‐mediated necrotizing myopathy.
Ameen Jubber, Maumer Durrani, Abdullah Almayahi, Kehinde Sunmboye   +3 more
doaj   +2 more sources

Anti‐signal recognition particle antibodies induce cardiac diastolic dysfunction via oxidative stress injury [PDF]

Clinical & Translational Immunology
Objectives Anti‐signal recognition particle (SRP) antibodies, markers of immune‐mediated necrotising myopathy, are reportedly related to cardiac involvement; however, whether they are pathogenic to the myocardium remains unclear.
Hao Zhang, Yunjing Shi, Yingze Fan, Dehao Zhu, Zeping Qiu, Huihui Chi, Qiongyi Hu, Liangzhe Xie, Yue Sun, Honglei Liu, Xiaobing Cheng, Junna Ye, Hui Shi, Zhuochao Zhou, Jianfen Meng, Jialin Teng, Chengde Yang, Wei Jin, Yutong Su   +18 more
doaj   +2 more sources

A signal recognition particle-related joint model of LASSO regression, SVM-RFE and artificial neural network for the diagnosis of systemic sclerosis-associated pulmonary hypertension [PDF]

Frontiers in Genetics, 2022
Background: Systemic sclerosis-associated pulmonary hypertension (SSc-PH) is one of the most common causes of death in patients with systemic sclerosis (SSc).
Jingxi Xu, Jingxi Xu, Chaoyang Liang, Jiangtao Li   +3 more
doaj   +2 more sources

Factors associated with refractory autoimmune necrotizing myopathy with anti-signal recognition particle antibodies [PDF]

Orphanet Journal of Rare Diseases, 2020
Background Autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (ANM-SRP) is regarded as refractory myositis, whereby some patients respond poorly to conventional immunosuppression and require B cell depletion treatment.
Yawen Zhao, Wei Zhang, Yilin Liu, Zhaoxia Wang, Yun Yuan   +4 more
doaj   +2 more sources

Signal Recognition Particle RNA Contributes to Oxidative Stress Response in Deinococcus radiodurans by Modulating Catalase Localization [PDF]

Frontiers in Microbiology, 2020
The proper functioning of many proteins requires their transport to the correct cellular compartment or their secretion. Signal recognition particle (SRP) is a major protein transport pathway responsible for the co-translational movement of integral ...
Runhua Han, Jaden Fang, Jessie Jiang, Elena K. Gaidamakova, Elena K. Gaidamakova, Rok Tkavc, Rok Tkavc, Rok Tkavc, Michael J. Daly, Lydia M. Contreras, Lydia M. Contreras   +10 more
doaj   +2 more sources

SRPassing Co-translational Targeting: The Role of the Signal Recognition Particle in Protein Targeting and mRNA Protection [PDF]

International Journal of Molecular Sciences, 2021
Andrey Karamyshev, Elena Tikhonova, Morgana K Kellogg   +2 more
exaly   +2 more sources

Recognition model and algorithm of projectiles by combining particle swarm optimization support vector and spatial-temporal constrain

Defence Technology, 2023
In order to improve the recognition rate and accuracy rate of projectiles in six sky-screens intersection test system, this work proposes a new recognition method of projectiles by combining particle swarm optimization support vector and spatial-temporal
Han-shan Li
doaj   +1 more source

Recognition of a signal peptide by the signal recognition particle [PDF]

Nature, 2010
Targeting of proteins to appropriate subcellular compartments is a crucial process in all living cells. Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome.
Janda, C, Li, J, Oubridge, C, Hernández, H, Robinson, C, Nagai, K   +5 more
openaire   +2 more sources

Interaction of signal-recognition particle 54 GTPase domain and signal-recognition particle RNA in the free signal-recognition particle [PDF]

Proceedings of the National Academy of Sciences, 2007
The signal-recognition particle (SRP) is a ubiquitous protein–RNA complex that targets proteins to cellular membranes for insertion or secretion. A key player in SRP-mediated protein targeting is the evolutionarily conserved core consisting of the SRP RNA and the multidomain protein SRP54. Communication between the SRP54 domains is
Tobias, Hainzl, Shenghua, Huang, A Elisabeth, Sauer-Eriksson   +2 more
openaire   +2 more sources

The Signal Recognition Particle Database (SRPDB) [PDF]

Nucleic Acids Research, 1993
This release of the SRPDB (signal recognition particle database, http://pegasus.uthct.edu/SRPDB/SRPDB . html ) adds four SRP RNA sequences (a total of 99 SRP RNA sequences), 23 SRP protein sequences (a total of 63 protein sequences from SRP9, SRP14, SRP19, SRP21, SRP54, SRP68 or SRP72), and, for the first time, sequences of the alpha subunit of the ...
Niels Larsen, Tore Samuelsson, Christian Zwieb   +2 more
openaire   +10 more sources