Results 41 to 50 of about 9,547,943 (379)
A multi‐scale approach reveals that NF‐κB cRel enforces a B‐cell decision to divide
Understanding the functions of multi‐cellular organs in terms of the molecular networks within each cell is an important step in the quest to predict phenotype from genotype.
Maxim N Shokhirev +6 more
doaj +1 more source
Optimization of resource allocation can explain the temporal dynamics and honesty of sexual signals [PDF]
In species in which males are free to dynamically alter their allocation to sexual signaling over the breeding season, the optimal investment in signaling should depend on both a male’s state and the level of competition he faces at any given time.
Blount, Jonathan D. +3 more
core +1 more source
Welcome to the Signal Integrity Column! In this issue, you will find a very interesting paper on power integrity. In modern high-speed digital designs, power distribution networks (PDNs) using power and ground planes are commonly used where decoupling capacitors are necessary to provide charge for logic transitions and, at the same time, to mitigate ...
openaire +2 more sources
Automated single-molecule imaging in living cells
Large scale live cell screens often lack single-molecule resolution. Here the authors present an artificial intelligence-assisted TIRF microscope with automated cell searching and focusing, and use it for high-throughput single-molecule imaging of EGFR ...
Masato Yasui +4 more
doaj +1 more source
Accumulation of α-synuclein aggregates in the substantia nigra pars compacta is central in the pathophysiology of Parkinson’s disease, leading to the degeneration of dopaminergic neurons and the manifestation of motor symptoms. Although several PD models
Olivier Lurette +10 more
doaj +1 more source
Paradigm of biased PAR1 (protease-activated receptor-1) activation and inhibition in endothelial cells dissected by phosphoproteomics [PDF]
Thrombin is the key serine protease of the coagulation cascade and mediates cellular responses by activation of PARs (protease-activated receptors). The predominant thrombin receptor is PAR1, and in endothelial cells (ECs), thrombin dynamically regulates
Hoogendijk, Arie J. +7 more
core +2 more sources
We present a quantum approach to a signaling game; a special kind of extensive games of incomplete information. Our model is based on quantum schemes for games in strategic form where players perform unitary operators on their own qubits of some fixed ...
Frackiewicz, Piotr
core +1 more source
A selection of (media) historic articles from film journals and articles on media in historic cultural journals.
openaire +7 more sources
Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles.
openaire +3 more sources
Trial Registration: ClinicalTrials.gov identifier: NCT01473524 ...
Gayatri Reghu +3 more
doaj +1 more source

