Results 101 to 110 of about 167,728,565 (254)

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

, 2015
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 4/18/15Official website of the Connecticut Judicial Selection Commission ...

core  

Revealing the selection history of adaptive loci using genome-wide scans for selection: an example from domestic sheep

BMC Genomics, 2018
Background One of the approaches to detect genetics variants affecting fitness traits is to identify their surrounding genomic signatures of past selection.
Christina Marie Rochus, Flavie Tortereau, Florence Plisson-Petit, Gwendal Restoux, Carole Moreno-Romieux, Gwenola Tosser-Klopp, Bertrand Servin   +6 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Selection Signature Analysis of Whole-Genome Sequences to Identify Genome Differences Between Selected and Unselected Holstein Cattle

Animals
A unique line of Holstein cattle has been maintained without selection in Minnesota since 1964. After many generations, unselected cattle produce less milk, but have better reproductive performance and health traits when compared with contemporary cows ...
Jiarui Cai, Liu Yang, Yahui Gao, George E. Liu, Yang Da, Li Ma   +5 more
doaj   +1 more source

Novel and known signals of selection for fat deposition in domestic sheep breeds from Africa and Eurasia.

PLoS ONE, 2019
Genomic regions subjected to selection frequently show signatures such as within-population reduced nucleotide diversity and outlier values of differentiation among differentially selected populations.
Salvatore Mastrangelo, Hussain Bahbahani, Bianca Moioli, Abulgasim Ahbara, Mohammed Al Abri, Faisal Almathen, Anne da Silva, Ibrahim Belabdi, Baldassare Portolano, Joram M Mwacharo, Olivier Hanotte, Fabio Pilla, Elena Ciani   +12 more
doaj   +1 more source

Identifying signatures of recent selection in Holstein cattle in the tropic

Revista Colombiana de Ciencias Pecuarias, 2018
Background: Holstein cattle have undergone strong selection processes in the world. These selection signatures can be recognized and utilized to identify regions of the genome that are important for milk yield.
Juan C. Rincón, Albeiro López, Julián Echeverri   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic diversity and selection signatures in sheep breeds

Natural and artificial selection in domesticated animals can cause specific changes in genomic regions known as selection signatures. Our study used the integrated haplotype score (iHS) and Tajima’s D tests within non-overlapping windows of 100 kb to ...
Watanabe, Rafael Nakamura [UNESP], Rodrigues, Julia Lisboa [UNESP], Berry, Donagh Pearse, Buzanskas, Marcos Eli [UNESP], Munari, Danísio Prado [UNESP], Braga, Larissa Graciano [UNESP], Schenkel, Flávio Schramm   +6 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission

, 2013
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 3/13/13Official website of the Connecticut Judicial Selection Commission ...

core