Results 61 to 70 of about 191,753 (296)

Selection signatures in goats reveal copy number variants underlying breed-defining coat color phenotypes [PDF]

, 2019
Domestication and human selection have formed diverse goat breeds with characteristic phenotypes. This process correlated with the fixation of causative genetic variants controlling breed-specific traits within regions of reduced genetic diversity, so ...
Schmocker, Corinne, Vidhya Jagannathan, Rashid Saif, Philippe Ammann (8033312), Erika Bangerter, Christine Flury, Dimitris Posantzis (8129901), Zafer Bulut, Bangerter, Erika, Cord Drögemüller, Henkel, Jan, Ursula Herren, Corinne Schmocker, Jan Henkel (8129883), Christine Flury (164251), Cord Drögemüller (132266), Jan Henkel, Posantzis, Dimitris, Flurina Zeindler (8129892), Erika Bangerter (8129895), Herren, Ursula, Saif, Rashid, Flury, Christine, Ursula Herren (8129898), Zafer Bulut (8129904), Tosso Leeb, Bulut, Zafer, Ammann, Philippe, Zeindler, Flurina, Jagannathan, Vidya, Jagannathan, Vidhya, Drögemüller, Cord, Leeb, Tosso, Rashid Saif (8129886), Vidhya Jagannathan (13914), Dimitris Posantzis, Corinne Schmocker (8129889), Flurina Zeindler, Tosso Leeb (81674), Philippe Ammann   +39 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Selection signatures and landscape genomics analysis to reveal climate adaptation of goat breeds

BMC Genomics
Goats have achieved global prominence as essential livestock since their initial domestication, primarily owing to their remarkable adaptability to diverse environmental and production systems.
Weifeng Peng, Yiyuan Zhang, Lei Gao, Wanlu Shi, Zi Liu, Xinyu Guo, Yunxia Zhang, Bing Li, Guoyin Li, Jingya Cao, Mingsheng Yang   +10 more
doaj   +1 more source

Group Signatures with Selective Linkability

, 2019
Group signatures allow members of a group to anonymously produce signatures on behalf of the group. They are an important building block for privacy-enhancing applications, e.g., enabling user data to be collected in authenticated form while preserving the user’s privacy. The linkability between the signatures thereby plays a crucial role for balancing
Garms, Lydia, Lehmann, Anja
openaire   +3 more sources

Selecting Parameters for the Rainbow Signature Scheme [PDF]

, 2010
Multivariate public key cryptography is one of the main approaches to guarantee the security of communication in a post-quantum world. One of the most promising candidates in this area is the Rainbow signature scheme, which was first proposed by J. Ding and D. Schmidt in 2005.
Albrecht Petzoldt, Stanislav Bulygin, Johannes Buchmann 0001   +2 more
openaire   +1 more source

Identification of Selection Signatures in Cattle Breeds Selected for Dairy Production [PDF]

Genetics, 2010
Abstract The genomics revolution has spurred the undertaking of HapMap studies of numerous species, allowing for population genomics to increase the understanding of how selection has created genetic differences between subspecies populations.
Stella A, AjmoneMarsan P, Lazzari B, Boettcher P   +3 more
openaire   +5 more sources

Runs of homozygosity and signatures of selection: a comparison among eight local Swiss sheep breeds.

, 2019
A dataset consisting of 787 animals with high-density SNP chip genotypes (346 774 SNPs) and 939 animals with medium-density SNP chip genotypes (33 828 SNPs) from eight indigenous Swiss sheep breeds was analyzed to characterize population structure ...
Burren, Alexander, Flury, C, Flury, Christine, A. Burren, Burren, A, Ammann, P., C. Drögemüller, Ammann, P, C. Flury, Drögemüller, Cord, Signer-Hasler, Heidi, H. Signer‐Hasler, P. Ammann, Drögemüller, C.   +13 more
core   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Runs of homozygosity in Italian Holstein bulls: a permutation approach and time-based mapping of the genomic regions potentially under selection

BMC Genomics
Background Runs of homozygosity (ROH) occurrence in animal genomes may result from a high level of relatedness within the population or from positive selection.
Laura Falchi, Alberto Cesarani, Luiz F. Brito, Salvatore Mastrangelo, Alfredo Pauciullo, Nicolò P. P. Macciotta, Giustino Gaspa   +6 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source