Results 1 to 10 of about 10,725 (262)

RETRACTED ARTICLE: The effects of sildenafil citrate on intrauterine growth restriction: a systematic review and meta-analysis [PDF]

open access: goldBMC Pregnancy and Childbirth, 2023
Background An increase in vascular resistance of uterine vessels is associated with intrauterine growth restriction (IUGR). Sildenafil citrate, a phosphodiesterase-5 inhibitor that stabilizes cyclic guanosine monophosphate (cGMP) and increases nitric ...
Yenlik Rakhanova   +3 more
doaj   +3 more sources

EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS [PDF]

open access: diamondBasrah Journal of Veterinary Research, 2009
Sildenafil citrate (Viagra) is an oral medication used to treat male impotence by the inhibition of phosphodiesterase-5 in the corpus cavernosum and subsequent facilitation of penile erection.
Khalid G. Al-Fartosi
doaj   +2 more sources

Retinal toxicity of long term overdose of sildenafil citrate: A case report [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports, 2023
Purpose: To report a case of eye structure changes in a patient with long-term overdose of sildenafil citrate. Observations: A 28-year-old male presented to our outpatient clinic with flare sensation in both eyes for 1 year after taking sildenafil ...
Huichao Yan, Wenzhen Yu
doaj   +2 more sources

Bioequivalence Studies of Sildenafil Citrate Orodispersible Film Administered with and without Water vs ViagraⓇ Film-Coated Tablets in Healthy Male Volunteers [PDF]

open access: yesCurrent Therapeutic Research, 2023
: Background: Orodispersible film (ODF) formulation offers ease of use, convenience of administration, and other advantages, especially for patients who have difficulty in swallowing or are on liquid restriction compared with conventional oral ...
Andrew Shaw, PhD   +10 more
doaj   +2 more sources

Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism [PDF]

open access: yesPharmaceutics, 2020
Sildenafil citrate is used to treat mild to moderate erectile dysfunction and premature ejaculation. However, it has low oral bioavailability, numerous adverse effects, and delayed onset of action.
Apichart Atipairin   +5 more
doaj   +2 more sources

Development and Validation of a Simple, Green Infrared Spectroscopic Method for Quantitation of Sildenafil Citrate in Siloflam Tablets of Unknown Manufacturing Formula [PDF]

open access: yesJournal of Analytical Methods in Chemistry, 2021
A simple, easy-to-implement, and green infrared spectroscopic method was developed and validated for the quantitative determination of sildenafil citrate in tablets of unknown manufacturing formula. Homogenized tablet powder with known mass content (%, m/
Van Trung Bui   +3 more
doaj   +2 more sources

The Weekend Drug; Recreational Use of Sildenafil Citrate and Concomitant Factors: A Cross-Sectional Study [PDF]

open access: yesFrontiers in Medicine, 2021
Background: Men who use erectile dysfunction medications for recreational purposes may be at increased risk of becoming psychologically dependent, which in turn could lead to psychogenic-based erectile dysfunction symptoms.
Berhanemeskel Weldegerima Atsbeha   +5 more
doaj   +2 more sources

Pharmacokinetic profile of sildenafil citrate in healthy Middle Eastern Males: Comparison with other ethnicities [PDF]

open access: yesSaudi Pharmaceutical Journal, 2021
Aim: 1) To investigate the pharmacokinetic profile of sildenafil citrate in Middle Eastern males and, 2) To highlight the impact of ethnicity on its pharmacokinetics parameters through comparing Middle Eastern data to the data estimated from different ...
Abdulrahman Alwhaibi   +5 more
doaj   +2 more sources

Effect of sildenafil citrate on treatment of infertility in women with a thin endometrium: a systematic review and meta-analysis [PDF]

open access: yesJournal of International Medical Research, 2020
Objective Endometrial thickness is a prognostic factor for successful pregnancy. This meta-analysis aimed to examine the role of sildenafil citrate on infertile women with a thin endometrium.
Xin Li   +6 more
doaj   +2 more sources

Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. [PDF]

open access: yesSci Rep, 2019
Age-related macular degeneration (AMD) - the leading cause of vision loss in the elderly - share many risks factors as atherosclerosis, which exhibits loss of vascular compliance resulting from aging and oxidative stress.
Yiu G   +8 more
europepmc   +4 more sources

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