Retinal toxicity of long term overdose of sildenafil citrate: A case report [PDF]
American Journal of Ophthalmology Case Reports, 2023 Purpose: To report a case of eye structure changes in a patient with long-term overdose of sildenafil citrate. Observations: A 28-year-old male presented to our outpatient clinic with flare sensation in both eyes for 1 year after taking sildenafil ...
Huichao Yan, Wenzhen Yu
doaj +2 more sources
BMC Pregnancy and Childbirth, 2023 Background An increase in vascular resistance of uterine vessels is associated with intrauterine growth restriction (IUGR). Sildenafil citrate, a phosphodiesterase-5 inhibitor that stabilizes cyclic guanosine monophosphate (cGMP) and increases nitric ...
Yenlik Rakhanova +3 more
doaj +2 more sources
Bioequivalence Studies of Sildenafil Citrate Orodispersible Film Administered with and without Water vs ViagraⓇ Film-Coated Tablets in Healthy Male Volunteers [PDF]
Current Therapeutic Research, 2023 : Background: Orodispersible film (ODF) formulation offers ease of use, convenience of administration, and other advantages, especially for patients who have difficulty in swallowing or are on liquid restriction compared with conventional oral ...
Andrew Shaw, PhD +10 more
doaj +2 more sources
Development of a Sildenafil Citrate Microemulsion-Loaded Hydrogel as a Potential System for Drug Delivery to the Penis and Its Cellular Metabolic Mechanism [PDF]
Pharmaceutics, 2020 Sildenafil citrate is used to treat mild to moderate erectile dysfunction and premature ejaculation. However, it has low oral bioavailability, numerous adverse effects, and delayed onset of action.
Apichart Atipairin +5 more
doaj +2 more sources
Development and Validation of a Simple, Green Infrared Spectroscopic Method for Quantitation of Sildenafil Citrate in Siloflam Tablets of Unknown Manufacturing Formula [PDF]
Journal of Analytical Methods in Chemistry, 2021 A simple, easy-to-implement, and green infrared spectroscopic method was developed and validated for the quantitative determination of sildenafil citrate in tablets of unknown manufacturing formula. Homogenized tablet powder with known mass content (%, m/
Van Trung Bui +3 more
doaj +2 more sources
The Weekend Drug; Recreational Use of Sildenafil Citrate and Concomitant Factors: A Cross-Sectional Study [PDF]
Frontiers in Medicine, 2021 Background: Men who use erectile dysfunction medications for recreational purposes may be at increased risk of becoming psychologically dependent, which in turn could lead to psychogenic-based erectile dysfunction symptoms.
Berhanemeskel Weldegerima Atsbeha +5 more
doaj +2 more sources
Pharmacokinetic profile of sildenafil citrate in healthy Middle Eastern Males: Comparison with other ethnicities [PDF]
Saudi Pharmaceutical Journal, 2021 Aim: 1) To investigate the pharmacokinetic profile of sildenafil citrate in Middle Eastern males and, 2) To highlight the impact of ethnicity on its pharmacokinetics parameters through comparing Middle Eastern data to the data estimated from different ...
Abdulrahman Alwhaibi +5 more
doaj +2 more sources
Effect of sildenafil citrate on treatment of infertility in women with a thin endometrium: a systematic review and meta-analysis [PDF]
Journal of International Medical Research, 2020 Objective Endometrial thickness is a prognostic factor for successful pregnancy. This meta-analysis aimed to examine the role of sildenafil citrate on infertile women with a thin endometrium.
Xin Li +6 more
doaj +2 more sources
Life, 2023 Sildenafil citrate, an oral drug used to treat erectile dysfunction, has low water solubility and oral bioavailability. The solubility is greatly influenced by the pH, changing from 37.25 mg/mL to 0.22 mg/mL with a change in pH from 1.2 to 8.0.
Chin-Yu Shih +4 more
doaj +1 more source
Sildenafil-triggered multi-culprit ST-segment elevation myocardial infarction: a case report [PDF]
Reviews in Cardiovascular Medicine, 2021 Sildenafil citrate and its generic forms are widely used to treat erectile dysfunction worldwide. Sildenafil citrate associated myocardial infarction is rarely reported in patients with no previous coronary artery disease. Herein, we present a case of
Byung Woo Yoon +1 more
doaj +1 more source