Results 31 to 40 of about 10,725 (262)

Evaluation of Addition Of Sildenafil Citrate On Fetal Growth And Doppler Indices In Treatment of Pregnancy Induced Hypertension [PDF]

Egyptian Journal of Medical Research, 2022
Pregnancy induced hypertension (PIH) is the most common complication during pregnancy and it affects up to 12% of pregnancies. It is the leading cause of maternal and fetal morbidity and mortality (1).
Eman Farid, Hamada Abdel-wahed, Heba Hemida   +2 more
doaj   +1 more source

Sildenafil Citrate-Restored eNOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/Nitrosative Stress [PDF]

, 2013
Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction.
Berkowitz, DE, Bivalacqua, TJ, Burnett, AL, Champion, HC, Hsu, LL, Musicki, B   +5 more
core   +3 more sources

The use of high performance anion exchange chromatography for the detection of counterfeit pharmaceutical products using the excipient content as a marker [PDF]

, 2015
The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients.
Beasley, Emma, Coleman, Tyler, Suman, Mandeesh   +2 more
core   +2 more sources

Oral bioavailability and pharmacokinetics of sildenafil citrate dry foam tablets in rats

Cogent Medicine, 2018
Sildenafil has low water solubility and oral bioavailability. Dry foam formulations of solid dosage forms of poorly water-soluble drugs may exhibit improved dissolution and bioavailability.
Somchai Sawatdee, Apichart Atipairin, Attawadee Sae Yoon, Teerapol Srichana, Narumon Changsan, Tan Suwandecha, Wirot Chanthorn, Atchara Phoem   +7 more
doaj   +1 more source

Effect of sildenafil in cavernous arteries of patients with erectile dysfunction

International Brazilian Journal of Urology, 2003
INTRODUCTION: Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction.
Joaquim A Claro, Sérgio F Ximenes, Archimedes Nardozza Jr, Enrico Andrade, Leonardo Messina, Miguel Srougi   +5 more
doaj   +1 more source

Effects and mechanisms of action of sildenafil citrate in human chorionic arteries

Reproductive Biology and Endocrinology, 2009
Objectives Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine growth retardation and for ...
Lynch Tadhg, O'Toole Daniel, Maharaj Chrisen H, Carney John, Jarman James, Higgins Brendan D, Morrison John J, Laffey John G   +7 more
doaj   +1 more source

If We Cannot Use Nitric Oxide for Newborn Persistent Pulmonary Hypertension, is Oral Sildenafil Therapeutic? A Single-center Experience

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Persistent pulmonary hypertension is still an issue in newborn period with different treatment strategies. In this study, we aimed to evaluate the three-year experience of a neonatal intensive care unit on use of sildenafil citrate for ...
Selçuk Gürel
doaj   +1 more source

cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. [PDF]

, 2015
Blocking Plasmodium falciparum transmission to mosquitoes has been designated a strategic objective in the global agenda of malaria elimination. Transmission is ensured by gametocyte-infected erythrocytes (GIE) that sequester in the bone marrow and at ...
A Dawn, A Heiber, A Merckx, A Pantaleo, A Sudo, AE Bianco, Audrey Lorthiois, Bernina Naissant, C Lavazec, C Lavazec, C Syin, Catherine Lavazec, CJ Taylor, D Yokoyama, DA Baker, David A. Baker, DK Muhia, Dominique Soldati-Favre, Donatella Taramelli, E Farfour, E Lasonder, E Ling, Eloise Thompson, F Hawking, F Silvestrini, F Silvestrini, Florence Breil, Florian Dupuy, G Deplaine, Ghania Ramdani, Gordon Langsley, HM Taylor, I Koshino, J Bain, K Leykauf, Kenneth Vernick, KM Tang, L Chen, L McRobert, L Wentzinger, LK Read, M Aingaran, M Boolell, M Hliscs, M Tiburcio, M Tiburcio, ME Smalley, MJ Lopez-Barragan, MK Dearnley, MW Dixon, N Goto, N Mohandas, Odile Mercereau-Puijalon, QL Fivelman, R Aguilar, R Joice, RE Sinden, RE Sinden, RL Coppel, Ross Cummings, RW Moon, S D'Alessandro, S Kunz, S Sanyal, SM Knebel, SP Davies, SP Kim, T Bousema, T Harrison, T Ono, T Seebeck, W Trager, WB Smith 2nd, Yoann Duffier, Yolanda Corbett   +74 more
core   +9 more sources

Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra((R))) in the treatment of erectile dysfunction in Brazilian and Mexican men [PDF]

, 2002
A 12-week, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of flexible-dose sildenafil citrate (Viagra((R))) treatment (25, 50 or 100 mg) in Brazilian and Mexican men with erectile dysfunction (ED) of broad-spectrum ...
Bertero, E., Claro, Joaquim, Damião, Ronaldo, Faria, Geraldo, Fregonesi, Adriano, Glina, S., Jaspersen, J., Mattos, Demerval, Mendoza, Antonio, Rocha, Luiz Carlos, Sotomayor, Mariano, Teloken, Cláudio, Ugarte, F., Ureta, S., Zonana, E.   +14 more
core   +1 more source

Micro-recanalization in a biodegradable graft for reconstruction of the vas deferens is enhanced by sildenafil citrate [PDF]

, 2010
This study investigated the effect of sildenafil citrate on micro-recanalization and neovascularization, which were previously demonstrated in a rat model using biodegradable grafts (BGs) for vas deferens reconstruction. A total of 24 male rats underwent
Ariza, Carlos, DeYoung, Barry, Griffith, Thomas, Holoch, Peter, Mallapragada, Surya, Mallapragada, Surya, Wald, Moshe   +6 more
core   +3 more sources